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Scientists develop technique to clear abnormal tau protein from human neurons

Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders.

10 Apr 2019

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic.

10 Apr 2019

Nicotine concentration in JUUL e-cigarette products is dangerously high, finds study

Little is known about the potential health effects of JUUL e-cigarette products that have recently risen in popularity, especially among adolescents.

9 Apr 2019

New Innovate UK funded project aims to develop biodegradable stents

A £1.1 million project to develop biodegradable stents for patients with severe vascular disease, which affects around one million people in the UK, has started thanks to Innovate UK funding.

9 Apr 2019

Study aims to improve our understanding of TGNC children

Issues surrounding gender identity in young children who are transgender or gender non-conforming are poorly understood because of the limited amount of research in this area.

9 Apr 2019

EEG of infants whose mothers has high stress levels show distinct pattern of brain activity

Does exposure to stress early in life affect a baby's brain development, and is there a way to single out babies who might benefit from early intervention?

9 Apr 2019

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

On a normal day, the cells of a human liver do what they do best - making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile.

9 Apr 2019

Dedicated intervention can double smoking quit rates for people with severe mental illness

Research published in the Lancet Psychiatry has found a dedicated intervention to help people with severe mental illness stop smoking can double quit rates at six months compared to standard care.

9 Apr 2019

MGH researchers provide insight into use of critical care resources

A study by Massachusetts General Hospital investigators has found wide variation in the use of different hospital units - intensive care or general medical units - to deliver a type of advanced respiratory support called non-invasive ventilation.

8 Apr 2019

Healthy diet pattern strongly associated with better physical function in old age

A person's ability to maintain independence and to physically care for themselves is an essential part of healthy aging.

8 Apr 2019

New clinical pathway reduces rate of debilitating complications for frail elderly trauma patients

A standardized interdisciplinary clinical pathway to identify and manage frailty in older patients has reduced the rate of one of the most debilitating complications for older patients--delirium--and kept patients from returning to the hospital within 30 days of treatment for traumatic injury.

5 Apr 2019

Study uncovers genetic causes of poor sleep

The international collaboration, led by the University of Exeter and published in Nature Communications, has found 47 links between our genetic code and the quality, quantity and timing of how we sleep. They include ten new genetic links with sleep duration and 26 with sleep quality.

5 Apr 2019

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

The Institute for Genome Sciences at the University of Maryland School of Medicine was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases to fund the IGS Genome Center for Infectious Diseases for another five years.

5 Apr 2019

Scientists use a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

5 Apr 2019

Researchers isolate compound that kills drug-resistant fungi from ant microbiota

Antimicrobial and antifungal resistance, which describe the ability of bacteria and other pathogens to resist the effects of drugs to which they were once sensitive, is a major public health problem worldwide.

5 Apr 2019

DBS improves patients' cognitive control by increasing power of brain rhythms

In a new study that could improve the therapeutic efficacy of deep-brain stimulation for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients' cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex.

4 Apr 2019

Bronchiectasis patients often display high sensitivity to airborne allergens

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) has found that patients with the lung disease bronchiectasis also often display sensitivity to airborne allergens, and has highlighted the particular role that fungi appear to play.

4 Apr 2019

Medical School News and Research

Scientists develop technique to clear abnormal tau protein from human neurons

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

Nicotine concentration in JUUL e-cigarette products is dangerously high, finds study

New Innovate UK funded project aims to develop biodegradable stents

Study aims to improve our understanding of TGNC children

EEG of infants whose mothers has high stress levels show distinct pattern of brain activity

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

Dedicated intervention can double smoking quit rates for people with severe mental illness

MGH researchers provide insight into use of critical care resources

Healthy diet pattern strongly associated with better physical function in old age

New clinical pathway reduces rate of debilitating complications for frail elderly trauma patients

Study uncovers genetic causes of poor sleep

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

Scientists use a promiscuous inhibitor to uncover cancer drug targets

Researchers isolate compound that kills drug-resistant fungi from ant microbiota

DBS improves patients' cognitive control by increasing power of brain rhythms

Bronchiectasis patients often display high sensitivity to airborne allergens

Hepatitis C-infected thoracic organs can be safely transplanted, study finds

Gene levels could be good indicator of prognosis in colorectal cancer patients

Simplifying Gene Expression Analysis in Neuroscience Research

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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