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HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

New findings could enable development of effective drugs for addiction with fewer side effects

Scientists from the Florida campus of The Scripps Research Institute have described findings that could enable the development of more effective drugs for addiction with fewer side effects.

3 Aug 2013

Longer looks: mayo's demands; 140 character death watch; posting hospital prices

Every week reporter Ankita Rao selects interesting reading from around the Web.

2 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Pain is defined by the sufferer’s experience. Pain may be severe because it is intense, frequent or sustained, and because it is distressing. The severity of pain is not simply due to what is going on in the joint, but is also affected by how the body processes the pain signals, and the context in which it is experienced.

31 Jul 2013

Researchers identify stem cells in urine can be directed to become multiple cell types

Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample? Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have identified stem cells in urine that can be directed to become multiple cell types.

31 Jul 2013

Research finds that aging elicits changes in taste preferences

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, found that aging elicits changes in taste preferences and that such changes appear to be independent of taste nerve activity.

31 Jul 2013

Study: About 50% of fibromyalgia patients have nerve damage

About half of a small group of patients with fibromyalgia - a common syndrome that causes chronic pain and other symptoms - was found to have damage to nerve fibers in their skin and other evidence of a disease called small-fiber polyneuropathy (SFPN). Unlike fibromyalgia, which has had no known causes and few effective treatments, SFPN has a clear pathology and is known to be caused by specific medical conditions, some of which can be treated and sometimes cured.

31 Jul 2013

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines for the treatment of chronic pain, is pleased to announce that its novel sodium channel blocker, CNV1014802 ('802), has been granted orphan-drug designation by the US Food and Drug Administration for the treatment of trigeminal neuralgia.

30 Jul 2013

NeuroSigma receives FDA approval to begin Phase III trial of Monarch eTNS System for epilepsy

NeuroSigma, Inc., today announced conditional approval by the U.S. Food and Drug Administration of its Investigational Device Exemption application to commence a Phase III pivotal trial of the Monarch eTNS System for treatment of drug resistant epilepsy.

30 Jul 2013

Elsevier announces winner of first Netter Atlas Medical Illustration Contest

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the winner of the first Netter Atlas Medical Illustration Contest.

26 Jul 2013

Study provides information on neural pathways involved in human word learning

Language is a uniquely human ability. The average vocabulary of a person consists of about thirty thousand words, although people show individual differences in their ability to learn a new language.

26 Jul 2013

Researchers find how brain cells communicate with each other in different voice tones

Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so frequently. Today National Institutes of Health researchers showed that brief bursts of chemical energy coming from rapidly moving power plants, called mitochondria, may tune brain cell communication.

26 Jul 2013

NeuroMetrix announces business and financial highlights for second quarter

NeuroMetrix, Inc. (the "Company"), a medical device company focused on the treatment of the neurological complications of diabetes, today reported business and financial highlights for the second quarter ended June 30, 2013.

25 Jul 2013

Neuroscience professor to receive Freedman Prize for exceptional contribution to mental health research

David Foster, Ph.D., an assistant professor of neuroscience at the Johns Hopkins University School of Medicine, will be awarded the 2013 Freedman Prize Honorable Mention for Exceptional Basic Research at an awards ceremony in New York City on July 26.

25 Jul 2013

Study finds that higher-frequency electric current stimulation of the spinal cord reduces pain faster

An animal study in the August issue of Anesthesiology suggests that higher-frequency electric current stimulation of the spinal cord reduced pain quicker and better reached nerves not affected by traditionally used frequencies. A higher frequency and intensity controlled pain faster and more effectively, the study found.

25 Jul 2013

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Scars are prone to appear at high tension parts, such as the sternum, shoulder and back, which are serious clinical problems. Surgeons reduce scar formation through Z, W, V-Y flap variation and reducing blade tension, but its specific mechanism are still not very clear.

25 Jul 2013

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.

25 Jul 2013

Enzyme in airway lining cells could hold key for asthma sufferers

An enzyme known for its role in heart disease may well be a promising target to treat asthma. Researchers from the University of Iowa have found that the enzyme, called CaMKII, is linked to the harmful effects of oxidation in the respiratory tract, triggering asthmatic symptoms.

25 Jul 2013

Dissecting recurrent laryngeal nerve during thyroid surgery significant for preventing nerve injury

Recurrent laryngeal nerve injury is the most common serious complication of thyroid surgery. Therefore, preventing recurrent laryngeal nerve injury is an important goal in thyroid surgery.

24 Jul 2013

Nerve News and Research

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

New findings could enable development of effective drugs for addiction with fewer side effects

Longer looks: mayo's demands; 140 character death watch; posting hospital prices

Transmembrane protein NG2 controls orientation of cell migration toward the wound

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Researchers identify stem cells in urine can be directed to become multiple cell types

Research finds that aging elicits changes in taste preferences

Study: About 50% of fibromyalgia patients have nerve damage

FDA grants orphan-drug designation to Convergence's CNV1014802 for treatment of TN

NeuroSigma receives FDA approval to begin Phase III trial of Monarch eTNS System for epilepsy

Elsevier announces winner of first Netter Atlas Medical Illustration Contest

Study provides information on neural pathways involved in human word learning

Researchers find how brain cells communicate with each other in different voice tones

NeuroMetrix announces business and financial highlights for second quarter

Neuroscience professor to receive Freedman Prize for exceptional contribution to mental health research

Study finds that higher-frequency electric current stimulation of the spinal cord reduces pain faster

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

Enzyme in airway lining cells could hold key for asthma sufferers

Dissecting recurrent laryngeal nerve during thyroid surgery significant for preventing nerve injury

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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