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Machine learning reveals distinct clinical states in pneumonia patients

Two patients being treated for pneumonia, an infection that causes difficulty breathing due to fluid-filled sacs in the lungs, can look vastly different and have opposing outcomes. Yet doctors struggle to accurately predict patients' prognoses and determine the most effective treatments.

29 Oct 2024

Boosting Treg cells shows promise in preventing recurrent pregnancy loss

Recurrent pregnancy loss can be devastating and exert a major impact on women, their partners, and society more broadly, but currently there are few options for effective therapies.

29 Oct 2024

AI model could help clinicians to understand prostate tumor's aggressiveness

Prostate cancer is the second most common cancer in men, and almost 300,000 individuals are diagnosed with it each year in the U.S.

29 Oct 2024

Study finds no benefit of routine orbital atherectomy in cardiac stenting

Routine use of an orbital atherectomy device to remove calcium from severely blocked coronary arteries before patients undergo cardiac stenting procedures does not improve outcomes, a Mount Sinai-led study has found.

29 Oct 2024

Urine transcriptomics: A new frontier for non-invasive genitourinary disease detection

Researchers explore the potential diagnostic utility of transcriptomic and metabolic signals in the genitourinary system.

29 Oct 2024

Research uncovers intrinsic factors influencing CAR-T cell success

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion product for B-ALL patients, is highly dependent on intrinsic features of the CAR-T cells themselves and their progression within the patient.

29 Oct 2024

Innovative method promises quick cancer diagnosis using ultrathin membranes

There are billions of tiny packets of cellular material called extracellular vesicles (EVs) that are produced by cells and released into each person's blood, saliva, and other bodily fluids.

29 Oct 2024

Could vitamin D be the missing link in managing type 2 diabetes? Recent study weighs in

Vitamin D's role in type 2 diabetes management is evolving, with evidence suggesting it may improve blood sugar levels and reduce diabetes-related inflammation.

29 Oct 2024

Genetic marker could revolutionize neonatal sepsis diagnosis

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study.

29 Oct 2024

A promising new strategy for malaria drug development

Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise.

29 Oct 2024

Researchers uncover the link between EVs and tissue damage

A landmark study led by WEHI and La Trobe University has found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our bodies.

29 Oct 2024

New genetic insights reveal kidney disease risk in West Africans

A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria.

28 Oct 2024

NIH grants $2.6 million to explore the effects of high blood-pressure drugs in CKD patients

The National Institutes of Health awarded a four-year, $2.6 million grant to researchers at Case Western Reserve University to study how high blood-pressure drugs affect patients with chronic kidney disease (CKD).

28 Oct 2024

Overcoming challenges in noninvasive diabetes management through wearable devices

Diabetes is an increasingly pervasive disease, currently affecting over 500 million adults worldwide. Since there is as yet no cure for type 1 or type 2 diabetes, patients must regularly monitor their BGLs to keep them in check.

28 Oct 2024

Weighing screening options for colorectal cancer in a changing landscape

Newly available blood tests to screen for colorectal cancer sound far more appealing than a standard colonoscopy. Instead of clearing your bowels and undergoing an invasive procedure, the tests require only a simple blood draw. But are the tests effective?

28 Oct 2024

Elucidating the mechanisms behind kidney development

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

28 Oct 2024