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AHF cautions against fast track FDA-approval for expanded use of Gilead’s Truvada

During its quarterly meeting over the weekend, The Board of Directors of the AIDS Healthcare Foundation (AHF) adopted a resolution cautioning Gilead Sciences against seeking fast track FDA-approval for the expanded use of its best selling AIDS treatment, Truvada, as a possible form of pre-exposure prophylaxis (PrEP) to prevent the transmission of HIV.

4 May 2011

RBC transfusion linked to improved survival after intracerebral hemorrhage

In patients with intracerebral hemorrhage —a type of stroke caused by bleeding inside the brain—transfusion with red blood cells may improve the chances of survival, reports a study in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

3 May 2011

Bill & Melinda Gates Foundation announces 88 new winners under Grand Challenges Exploration program

The Bill & Melinda Gates Foundation today announced 88 new winners of US$100,000 each to support innovative research that has the potential to dramatically improve lives in some of the world's poorest countries. The funding, made possible through the Grand Challenges Exploration (GCE) program, will enable researchers worldwide to test unorthodox ideas that address persistent health and development challenges.

30 Apr 2011

Fetal exposure to crude oil chemical may increase risk of heart disease

While it may be years before the health effects of the 2010 oil spill in the Gulf of Mexico are known, a new study shows that fetal exposure to a chemical found in crude oil is associated with an increased risk of congenital heart disease.

30 Apr 2011

Senomyx first-quarter 2011 revenues rise up 13%

Senomyx, Inc., a company focused on using proprietary taste receptor-based technologies to discover novel flavor ingredients for the food, beverage, and ingredient supply industries, today provided a corporate update and reported financial results for the first quarter ended March 31, 2011.

30 Apr 2011

Injecting tissue spacers reduces risk of radiation burns to rectum in prostate cancer patients

Injecting a tissue spacer in the prostate-rectal inter-space is an effective way to reduce the rectal dose for prostate cancer patients receiving radiation therapy, according to research presented April 30, 2011, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. This symposium is sponsored by the American Society for Radiation Oncology (ASTRO) and Radiological Society of North America (RSNA).

29 Apr 2011

New PET imaging clinical trial to improve early esophageal, lung cancer detection

Can a simple imaging test help predict the success of cancer treatment, even before the treatment is complete? To begin to answer this question, a new National Cancer Institute-funded clinical trial is using a novel PET imaging technique that could improve the early detection of tumor growth during treatment for esophageal and lung cancer.

29 Apr 2011

Softgels as effective as tablets in delivering folic acid

Folic acid, an essential vitamin formulated to be part of a multivitamin + DHA liquid softgel capsule, is absorbed and available within the body in amounts similar to folic acid formulated for solid tablets, according to a study presented in a late breaking session at the Experimental Biology (EB) 2011 annual meeting.

28 Apr 2011

Cotinine can reduce plaques linked with dementia and prevent memory loss

Cotinine, a compound derived from tobacco, reduced plaques associated with dementia and prevented memory loss in a mouse model of Alzheimer's disease, a study led by researchers at Bay Pines VA Healthcare System and the University of South Florida found.

28 Apr 2011

Researchers begin approved drugs screening for clinical use against rare diseases

Researchers have begun screening the first definitive collection of thousands of approved drugs for clinical use against rare and neglected diseases. They are hunting for additional uses of the drugs hoping to find off-label therapies, for some of the 6,000 rare diseases that afflict 25 million Americans.

28 Apr 2011

Tips for parents to identify concussions in young athletes

A recent study found that many parents feel they lack the knowledge to adequately detect symptoms of head injuries in their children. Yet keeping young athletes off the field until they've fully healed from a concussion is key to preventing serious and potentially fatal complications.

27 Apr 2011

Rxi secures SBIR grants to develop novel RNAi therapeutics for ALS

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted and immunotherapy technologies, today announced that it was awarded two Small Business Innovation Research grants from the National Institutes of Health.

27 Apr 2011

ISC-4 topical compound may prevent skin cancer lesion formation

While incidents of melanoma continue to increase despite the use of sunscreen and skin screenings, a topical compound called ISC-4 may prevent melanoma lesion formation, according to Penn State College of Medicine researchers.

27 Apr 2011

Cholesterol-lowering drugs may help clot-busting drugs treat strokes

Cholesterol-lowering drugs known as statins may help clot-busting drugs treat strokes, according to researchers at Washington University School of Medicine in St. Louis.

27 Apr 2011

New angle in cause of tuberculosis discovered - scientists hopeful for new therapy

In a new study published Monday, researchers from the US have isolated the enzyme that allows tuberculosis to destroy lung tissue. This discovery could speed the search for treatments.

26 Apr 2011

USPTO grants Cortex patent for CX1739 AMPAKINE molecule

Cortex Pharmaceuticals, Inc. announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance for a patent that protects its lead AMPAKINE® molecule, CX1739.

26 Apr 2011

Anti-inflammatory drugs reduce effectiveness of widely used antidepressant medications

Scientists at the Fisher Center for Alzheimer's Disease Research at The Rockefeller University, led by Paul Greengard, Ph.D., and Jennifer Warner-Schmidt, Ph.D., have shown that anti-inflammatory drugs, which include ibuprofen, aspirin and naproxen, reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors, or SSRIs, taken for depression and obsessive-compulsive disorder and anxiety disorders.

26 Apr 2011

Alkem, Karo Bio partner to license eprotirome

Karo Bio has entered into a collaboration and license agreement with the Indian pharmaceutical company Alkem Laboratories Ltd.

26 Apr 2011

BMY to present belatacept Phase III new data at American Transplant Congress

New data on belatacept, an investigational selective T cell costimulation blocker being studied for use in renal transplantation by Bristol-Myers Squibb Company, will be presented at the American Transplant Congress April 30 - May 4, 2011 in Philadelphia.

26 Apr 2011

Curemark CM-182 demonstrates positive results for schizophrenia in transgenic chakragati model of psychosis

Curemark, LLC, a drug research and development company focused on the treatment of neurological diseases, announced today that its compound CM-182 demonstrated positive results for schizophrenia in the transgenic chakragati (ckr) model of psychosis. The mouse model screening was performed by the Contract Research Organization, Cerca Insights.

25 Apr 2011

Compound News and Research

AHF cautions against fast track FDA-approval for expanded use of Gilead’s Truvada

RBC transfusion linked to improved survival after intracerebral hemorrhage

Bill & Melinda Gates Foundation announces 88 new winners under Grand Challenges Exploration program

Fetal exposure to crude oil chemical may increase risk of heart disease

Senomyx first-quarter 2011 revenues rise up 13%

Injecting tissue spacers reduces risk of radiation burns to rectum in prostate cancer patients

New PET imaging clinical trial to improve early esophageal, lung cancer detection

Softgels as effective as tablets in delivering folic acid

Cotinine can reduce plaques linked with dementia and prevent memory loss

Researchers begin approved drugs screening for clinical use against rare diseases

Tips for parents to identify concussions in young athletes

Rxi secures SBIR grants to develop novel RNAi therapeutics for ALS

ISC-4 topical compound may prevent skin cancer lesion formation

Cholesterol-lowering drugs may help clot-busting drugs treat strokes

New angle in cause of tuberculosis discovered - scientists hopeful for new therapy

USPTO grants Cortex patent for CX1739 AMPAKINE molecule

Anti-inflammatory drugs reduce effectiveness of widely used antidepressant medications

Alkem, Karo Bio partner to license eprotirome

BMY to present belatacept Phase III new data at American Transplant Congress

Curemark CM-182 demonstrates positive results for schizophrenia in transgenic chakragati model of psychosis

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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