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CUMC's Laboratory of Personalized Genomic Medicine granted approval for Columbia Combined Cancer Panel

The Laboratory of Personalized Genomic Medicine at Columbia University Medical Center has been granted full approval by the New York State Department of Health for the Columbia Combined Cancer Panel, (CCCP). This panel queries 467 cancer-related genes and was designed in collaboration with Columbia University Medical Center oncologists.

25 Sep 2015

Pabetalone (RVX-208) to be tested in proof-of-concept pilot study in complement mediated diseases

Resverlogix Corp. announced today the commencement of an Orphan Disease Program specific for Complement Mediated Diseases. New data generated by Resverlogix has demonstrated that BET inhibition by apabetalone (RVX-208) has effects on multiple biological pathways that underlie disease pathology.

24 Sep 2015

New technique allows scientists to see blood-forming stem cells present in the bone marrow

A team of scientists at the Children's Research Institute at UT Southwestern has become the first to use a tissue-clearing technique to localize a rare stem cell population, in the process cracking open a black box containing detailed information about where blood-forming stem cells are located and how they are maintained.

24 Sep 2015

Hyperbaric oxygen therapy improves outcomes of umbilical cord blood transplant patients

For the past 27 years, cord blood transplants have been a life-saving treatment option for thousands of people with leukemia, non-Hodgkins lymphoma, Hodgkins disease and myelodysplastic disorders. Cord blood helps replace cancerous blood cells and replenish a patient's own bone marrow and immune system. Even with its success, researchers are continually looking for ways to improve the transplant process and increase cure rates.

24 Sep 2015

City of Hope receives gift to open new Judy and Bernard Briskin Center for Multiple Myeloma Research

The Judy and Bernard Briskin Family Foundation has announced a gift to launch the new Judy and Bernard Briskin Center for Multiple Myeloma Research at City of Hope, the third named center within City of Hope's new Hematologic Malignancies and Stem Cell Transplantation Institute. The generous gift will enable the institution to further its already considerable accomplishments in the field of myeloma treatment and research.

24 Sep 2015

Practical tips to help parents spot children's foot problems

Just part of growing up vs. the sign of a problem—managing children's health and wellness is complicated for parents, who often struggle to know which signs and symptoms are temporary and those that point to more serious concerns. As parents transition back to the regular routines of fall with school and sports, the American College of Foot and Ankle Surgeons offers practical tips to help parents know what their children's feet are telling them.

23 Sep 2015

Study demonstrates potential of FCPCs as new source for cartilage regeneration

The self-repair of injured cartilage is difficult for several reasons, foremost of which is the lack of blood supply to the tissue. Therapeutic efforts aimed at cartilage repair are often not optimal. Surgical repair techniques often lead to the formation of fibrocartilage, which is weaker and less durable. Although cell transplantation aimed at cartilage repair has been carried out using mesenchymal stem cells (MSCs), varying outcomes have resulted, despite the propensity of MSCs to proliferate and differentiate.

23 Sep 2015

$Bisphosphonate drugs linked to greater risk of atypical hip fractures$

Bisphosphonate drugs linked to greater risk of atypical hip fractures

The use of bisphosphonates, a group of drugs used to prevent hip breakages in women with osteoporosis, is associated with an increased risk of atypical fractures in this joint, understood as those that occur in less frequent locations.

22 Sep 2015

Study uncovers new mechanisms that regulate immune cells

The proteins CD47 and SIRPα are fundamental to establishing a correct number of immune cells, so-called B lymphocytes. This according to a dissertation by Shrikant Shanital Kolan from Umeå University in Sweden.

22 Sep 2015

Bretuximab vedotin safe, effective for older Hodgkin lymphoma patients unfit for chemotherapy

A study, published online in Blood, the Journal of the American Society of Hematology, reports that bretuximab vedotin is an effective and safe first course of treatment for older Hodgkin lymphoma patients unfit for chemotherapy.

22 Sep 2015

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Research comparing clinical outcomes between patients receiving nafcillin and cefazolin for treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia shows that overall treatment failure rate among patients receiving cefazolin was no worse than nafcillin, and significantly fewer adverse effects were documented for those receiving cefazolin.

22 Sep 2015

$Common Alzheimer's disease drug increases bone density, reduces fracture risks$

Common Alzheimer's disease drug increases bone density, reduces fracture risks

The most common drug used to treat Alzheimer's disease increases bone mass in mice, according to one of the first research articles published in the new open access journal Heliyon. The authors of the study, from Saitama Medical University in Japan, say this means the drug could also be used to treat bone loss diseases like osteoporosis and periodontitis, following further clinical research.

21 Sep 2015

NAMS recognizes outstanding contributions to the field of women's health, menopause

The North American Menopause Society is pleased to announce the recipients of the Society's 2015 awards that recognize outstanding contributions to the field of women's health and menopause. The recipients will be acknowledged during the NAMS 26th Annual Meeting, in Las Vegas, NV, from September 30 through October 3, 2015.

21 Sep 2015

CTCA at Western begins clinical trial that combines immunotherapy with chemotherapy to target sarcomas

Cancer Treatment Centers of America at Western Regional Medical Center in Goodyear, Arizona, has begun Phase II of another arm of its multi-arm clinical trial that combines immunotherapy with chemotherapy.

21 Sep 2015

Technology enabling fewer invasive cardiac procedures benefits Glasgow children

Clinicians at Glasgow’s Royal Hospital for Sick Children are now able to scan patients’ hearts in just one heartbeat thanks to the installation of GE Healthcare’s Revolution* CT. The technology’s ability to freeze the heart’s motion helps to produce high quality diagnostic images, even for patients with erratic or high heart rates which may have led to poor quality images in the past. This helps reduce the need for invasive examination procedures and allows for quick and confident diagnoses of heart disease.

17 Sep 2015

Amgen, Xencor partner to develop and commercialize new therapeutics for cancer immunotherapy, inflammation

Amgen and Xencor, Inc. announced today that the two companies have entered into a research and license agreement to develop and commercialize novel therapeutics in the areas of cancer immunotherapy and inflammation.

16 Sep 2015

Exosomes provide a promising way to induce human stem cell differentiation

Regenerative medicine using stem cells is an increasingly promising approach to treat many types of injury. Transplanted stem cells can differentiate into just about any other kind of cell, including neurons to potentially reconnect a severed spinal cord and repair paralysis.

16 Sep 2015

USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

Stroke injures the brain, but a new University of South Florida study indicates an abdominal organ that plays a vital role in immune function, the spleen, may be a target for treating stroke-induced chronic inflammation leading to further brain cell death.

16 Sep 2015

Orthocell presents successful ‘cell factory’ data at European Bone and Joint Infection Society

Regenerative medicine company Orthocell Limited is pleased to announce the presentation of its successful ‘cell factory’ data at the European Bone and Joint Infection Society in Estoril Portugal September 2015.

16 Sep 2015

Researchers develop 3D bone marrow that produces functional human platelets ex vivo

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering at Tufts University and their collaborators have successfully developed a 3-dimensional (3D) tissue-engineered model of bone marrow that can produce functional human platelets outside the body (ex vivo).

16 Sep 2015

Bone News and Research

CUMC's Laboratory of Personalized Genomic Medicine granted approval for Columbia Combined Cancer Panel

Pabetalone (RVX-208) to be tested in proof-of-concept pilot study in complement mediated diseases

New technique allows scientists to see blood-forming stem cells present in the bone marrow

Hyperbaric oxygen therapy improves outcomes of umbilical cord blood transplant patients

City of Hope receives gift to open new Judy and Bernard Briskin Center for Multiple Myeloma Research

Practical tips to help parents spot children's foot problems

Study demonstrates potential of FCPCs as new source for cartilage regeneration

Bisphosphonate drugs linked to greater risk of atypical hip fractures

Study uncovers new mechanisms that regulate immune cells

Bretuximab vedotin safe, effective for older Hodgkin lymphoma patients unfit for chemotherapy

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Common Alzheimer's disease drug increases bone density, reduces fracture risks

NAMS recognizes outstanding contributions to the field of women's health, menopause

CTCA at Western begins clinical trial that combines immunotherapy with chemotherapy to target sarcomas

Technology enabling fewer invasive cardiac procedures benefits Glasgow children

Amgen, Xencor partner to develop and commercialize new therapeutics for cancer immunotherapy, inflammation

Exosomes provide a promising way to induce human stem cell differentiation

USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

Orthocell presents successful ‘cell factory’ data at European Bone and Joint Infection Society

Researchers develop 3D bone marrow that produces functional human platelets ex vivo

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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