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Impact of the Omicron variant on disease severity and healthcare utilization

Researchers compare trends in disease and hospital utilization during Omicron circulation to the previous SARS-CoV-2 variants in the U.S.

28 Jan 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age.

28 Jan 2022

Unhealthy vaginal microbiome in mothers may contribute to infant deaths and altered development

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.

27 Jan 2022

Exposure to unconventional oil and gas development linked to higher risk of early mortality

Elderly people living near or downwind of unconventional oil and gas development (UOGD)—which involves extraction methods including directional (non-vertical) drilling and hydraulic fracturing, or fracking—are at higher risk of early death compared with elderly individuals who don't live near such operations, according to a large new study from Harvard T.H. Chan School of Public Health.

27 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Researchers show that the CHI3L1 inhibitors reduce epithelial cell infection by SARS-CoV-2 VOC pseudovirus moieties.

27 Jan 2022

Significance of metabolic parameters in COVID-19 prognosis

In a new study, researchers evaluated the significance of metabolic parameters in determining COVID-19 prognosis.

27 Jan 2022

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

This study aimed to assess the impact of full vaccination with additional and booster doses.

27 Jan 2022

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

A recent study was published where CFR was assessed for COVID-19 vaccine effectivity

27 Jan 2022

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

For nearly three decades, John Pierce Wise Sr. has investigated the connection between exposure to metals and cancer, working both in the lab and in the field, reporting significant discoveries about the effects of metals on chromosomes in lung cancer and how those effects differ in humans and in whales.

27 Jan 2022

Following heart-healthy lifestyle behaviors can support good brain health

The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer's disease and dementia, according to the American Heart Association's Heart Disease and Stroke Statistics - 2022 Update, published today in the Association's flagship, peer-reviewed journal Circulation.

27 Jan 2022

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Strict COVID-19 lockdown policies such as workplace closures in European cities reduced levels of air pollution and the number of associated deaths, according to new estimates published in Nature's Scientific Reports.

27 Jan 2022

Death rates from ovarian cancer are predicted to fall by 2022 in EU countries

Death rates from ovarian cancer are predicted to fall by 17% in the UK and by 7% in EU countries in 2022 compared to 2017, according to new research published in the leading cancer journal Annals of Oncology today (Wednesday).

27 Jan 2022

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

The researchers described COV50, a urinary biomarker, that can predict death and disease progression in COVID-19.

26 Jan 2022

New research on SARS-CoV-2 Omicron and care home residents

Researchers find a reduced risk of hospitalizations and deaths in long term care facility residents infected with SARS-CoV-2 Omicron variant.

26 Jan 2022

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

A team of researchers performed a meta-analysis to investigate the use of remdesivir in the treatment of COVID-19.

26 Jan 2022

Exploring hematological alterations in COVID-19 patients

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality.

26 Jan 2022

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells.

26 Jan 2022

Mortality News and Research

Impact of the Omicron variant on disease severity and healthcare utilization

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Unhealthy vaginal microbiome in mothers may contribute to infant deaths and altered development

Exposure to unconventional oil and gas development linked to higher risk of early mortality

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Significance of metabolic parameters in COVID-19 prognosis

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

Following heart-healthy lifestyle behaviors can support good brain health

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Death rates from ovarian cancer are predicted to fall by 2022 in EU countries

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

New research on SARS-CoV-2 Omicron and care home residents

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

Exploring hematological alterations in COVID-19 patients

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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