Protein C News and Research

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Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Exploring diverse ancestry is a critical factor in furthering medical research.

25 May 2023

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer's disease, fails to protect the brain from inflammation.

25 May 2023

Immune cells targeting core protein play an important role in early immune defense against COVID-19

LMU immunologists have studied the early immune response to acute SARS-CoV-2 infection and show how vaccines could be improved in future.

25 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

Manipulating a signaling protein to slow down muscular dystrophy

A team of researchers at the University of Houston College of Pharmacy is reporting that by manipulating TAK1, a signaling protein that plays an important role in development of the immune system, they can slow down disease progression and improve muscle function in Duchenne muscular dystrophy (DMD).

25 May 2023

New method can kill aggressive brain tumors

Researchers at the University of Gothenburg, working with French colleagues, have successfully developed a method able to kill the aggressive brain tumor glioblastoma.

25 May 2023

Does long-term exposure to air pollution impact cardiometabolic health markers?

The relationship between exposure to air pollution and its impact on cardiometabolic health markers.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

High alcohol consumption could have detrimental effects on muscle mass in later life

Heavy drinkers could be putting themselves at risk of muscle loss and frailty in later life, according to new research from the University of East Anglia.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Keto vs. low-fat diets: which is more sustainable in the long term?

Researchers investigated whether commercial weight loss diets meet nutrient requirements.

24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation.

23 May 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

Higher intake of flavonol-rich foods linked to lower odds of developing frailty

Eating plant-based foods that contain dietary compounds called flavonols can lower your chances of developing frailty.

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Protein C News and Research

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

Immune cells targeting core protein play an important role in early immune defense against COVID-19

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Manipulating a signaling protein to slow down muscular dystrophy

New method can kill aggressive brain tumors

Does long-term exposure to air pollution impact cardiometabolic health markers?

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

High alcohol consumption could have detrimental effects on muscle mass in later life

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Combination of genetic and environmental factors increases the risk of cleft lip

Scientists study the structure and function of a transporter involved in cancer, immunity

Keto vs. low-fat diets: which is more sustainable in the long term?

The adaptive immunity of human endemic viruses

The antimicrobial potential of nanoparticles

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

Study findings offer hope for the development of novel treatments for leishmaniasis

Higher intake of flavonol-rich foods linked to lower odds of developing frailty

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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