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Key sequence in killer cells captured by Andor revolution microscope

Although much is known of the immune response to antigen-presenting cells, until now the way the body's own killer cells establish an immunological synapse to destroy those target cells has remained unclear. Now, an international research team led by Professor Gillian Griffiths of Cambridge University has resolved the key sequence of events using high-resolution 4D imaging.

15 Sep 2015

Population health study examines real-world osteoporosis treatment patterns

A statewide study has found that from 2005 to 2012, fewer than a quarter of men and women with documentation of osteoporosis or fragility fracture, conditions for which national guidelines would recommend treatment for osteoporosis, actually received that treatment.

15 Sep 2015

$Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture$

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

Using extensive genetic data compiled by the UK10K project, an international team of researchers led by Dr. Brent Richards of the Lady Davis Institute at the Jewish General Hospital has identified a genetic variant near the gene EN1 as having the strongest effect on bone mineral density (BMD) and fracture identified to date.

15 Sep 2015

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Stem cell therapies are often limited by low survival of transplanted stem cells and the lack of precise control over their differentiation into the terminal cell types needed to repair or replace injured tissues. Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph.D., has developed a new strategy - embedding stem cells into porous, transplantable hydrogels - that has experimentally improved bone repair by boosting the survival rate of transplanted stem cells and influencing their cell differentiation.

15 Sep 2015

GE Silent Scan MRI technology now available at St. Luke’s Warren Campus

Magnetic Resonance Imaging (MRI) is a radiology study used to help diagnose a variety of injuries and illness, including headaches and head injuries. For patients with headaches and those sensitive to sound, the audible noise during the actual test may be mildly annoying or downright stressful.

15 Sep 2015

Scientists identify a gene that can cause more aggressive cancer in AML patients

University of Manchester scientists have identified a gene - FOXC1 - that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients, according to a Cancer Research UK study published in the journal Cancer Cell, today (Monday).

14 Sep 2015

New study reveals that social factors may impact critical aspects of health in AML patients

A new study reveals that insurance status, marital status, and county-level income may affect the chances of survival in young patients with acute myelogenous leukemia (AML). Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings indicate that efforts are needed to address the social factors that impact critical aspects of health in these patients.

14 Sep 2015

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

One week ago, surgical teams took part in a record-setting day of organ transplantation at Baylor University Medical Center at Dallas. Surgeons on the medical staff performed nine organ transplants on seven patients in one calendar day.

11 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.

11 Sep 2015

Innovative technologies offer hope to people living with chronic pain

More than 100 million people in this country have pain that won't go away. Many of these chronic pain sufferers fail to get relief from pills, shots and even surgery, while others temporarily trade the pain for side effects such as drowsiness or digestive problems.

11 Sep 2015

Johns Hopkins Kimmel Cancer Center to break ground on new cancer care building in East Baltimore

The Johns Hopkins Kimmel Cancer Center will break ground Sept. 10 on a new $100 million, 184,000-square-foot cancer care building at one of the highest elevations in East Baltimore.

11 Sep 2015

Patient society representatives to gather in Athens, Greece for the opening of IOF-WWC 2015

Patient society representatives from all regions of the world will gather in Athens, Greece for the opening of the 15th IOF Worldwide Conference of Osteoporosis Patient Societies on Friday September 11.

10 Sep 2015

Simple stem cell production method shows promise in mice for treating IPF

In a small pilot study, researchers from North Carolina State University have demonstrated a rapid, simple way to generate large numbers of lung stem cells for use in disease treatment. This method of harvesting and growing a patient's own lung stem cells shows promise in mice for treating idiopathic pulmonary fibrosis (IPF), and could one day provide human IPF sufferers with an effective, less invasive method of treatment for their disease.

10 Sep 2015

New $2.8 million NIH grant to help researchers find better treatments for hemorrhagic strokes

Developing better treatments and an improved understanding of the biology behind brain injury from hemorrhagic strokes is the main goal of a three-year $2.8 million grant to the Translational Genomics Research Institute, Phoenix Children's Hospital, and Barrow Neurological Institute.

9 Sep 2015

Poor mental health, self-harm and suicide attempts common among child trafficking survivors

Poor mental health, self-harm and suicide attempts are common among children and adolescents who have been trafficked for forced labour or sexual exploitation, according to a new study published in JAMA Pediatrics.

9 Sep 2015

UCSF researchers lead $10 million research project on pediatric cancer

Researchers at UC San Francisco are leading a five-year, $10 million research project dedicated to pediatric cancer, funded by the first grant of its kind to focus on a molecular pathway that underlies many cancers rather than on a cancer in a particular organ or tissue in the body.

9 Sep 2015

Bone News and Research

Key sequence in killer cells captured by Andor revolution microscope

Population health study examines real-world osteoporosis treatment patterns

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

New strategy improves bone repair by boosting survival rate of transplanted stem cells

GE Silent Scan MRI technology now available at St. Luke’s Warren Campus

Scientists identify a gene that can cause more aggressive cancer in AML patients

New study reveals that social factors may impact critical aspects of health in AML patients

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

Penn Medicine researchers show that DNA editing errors can lead to cancer

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Innovative technologies offer hope to people living with chronic pain

Johns Hopkins Kimmel Cancer Center to break ground on new cancer care building in East Baltimore

Patient society representatives to gather in Athens, Greece for the opening of IOF-WWC 2015

Simple stem cell production method shows promise in mice for treating IPF

New $2.8 million NIH grant to help researchers find better treatments for hemorrhagic strokes

Poor mental health, self-harm and suicide attempts common among child trafficking survivors

UCSF researchers lead $10 million research project on pediatric cancer

CHAM, AECC receive $1.3 million NCI grant to advance more effective bone cancer treatments for children

New study reveals effect of diabetes drug on bone health, benefit of exercise in mice

SKY92 genetic subtyping signature better than current markers in predicting progress of multiple myeloma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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