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Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

8 Sep 2015

Appropriate pre-surgical physical therapy can help joint replacement patients recover faster

For people contemplating a hip or knee replacement, the prospect of a long post-surgical recovery can be a daunting one. The grueling rehabilitation sessions, the frustration of re-learning everyday movements, the weeks of waiting to return to "normal"— it's almost enough to make patients reconsider surgery.

3 Sep 2015

Imetelstat drug shows promise in treating patients with myelofibrosis

Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.

3 Sep 2015

Researchers perform first focused ultrasound treatments in the U.S. for dyskinesia

Researchers at the University of Maryland and the University of Virginia have performed the first focused ultrasound treatments in the United States for dyskinesia associated with Parkinson's disease.

2 Sep 2015

Researchers discover that vitamin D may play significant role in preventing AMD among women

Vitamin D has been studied extensively in relation to bone health as well as cancer. Now, a team led by a researcher at the University at Buffalo has discovered that vitamin D may play a significant role in eye health, specifically in the possible prevention of age-related macular degeneration, or AMD, among women who are more genetically prone to developing the sight-damaging disease.

1 Sep 2015

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

Study: Knee or hip replacement surgery may increase heart attack risk

Contrary to recent reports, Boston-based researchers found that osteoarthritis patients who had total knee or hip joint replacement surgery, known as arthroplasty, were at increased risk of heart attack (myocardial infarction) in the early post-operative period.

31 Aug 2015

Scientists discover the oldest case of leukemia in prehistoric female skeleton

Scientists of the Senckenberg Center for Human Evolution and Paleoenvironment and the University of Tübingen have discovered what may well be the oldest known case of Leukemia.

31 Aug 2015

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Researchers have discovered how a common mutation in a high-risk leukemia subtype drives the cancer's aggressiveness and have identified drugs that may work with existing precision medicines to improve survival. St. Jude Children's Research Hospital scientists led the study, which was published online today in the journal Cancer Cell.

28 Aug 2015

Soligenix obtains additional funding from NIAID to advance development of OrbeShield for GI ARS treatment

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that the National Institute of Allergy and Infectious Diseases has exercised its option to advance preclinical development of OrbeShield (oral beclomethasone 17,21-dipropionate or oral BDP).

27 Aug 2015

Centenary Institute develops new therapeutic approach to prevent GVHD in blood cancer patients

Sydney’s Centenary Institute has developed a new therapeutic approach that could help to improve outcomes for patients undertaking treatment for blood cancer.

26 Aug 2015

Novartis receives FDA approval for expanded use of Promacta for younger children with rare blood disorder

Novartis announced today that the US Food and Drug Administration has approved an expanded use for Promacta to include children 1 year of age and older with chronic immune thrombocytopenia who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy.

26 Aug 2015

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the August 25 issue of JAMA.

26 Aug 2015

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an increased risk of relapse and poor survival.

26 Aug 2015

Amedica announces release of Valeo II LL interbody fusion device

Amedica Corporation, an innovative biomaterial company which develops and manufactures silicon nitride as a platform for biomedical applications, is pleased to announce the release of its silicon nitride lateral lumbar interbody fusion device.

26 Aug 2015

Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

Clementia Pharmaceuticals, Inc. today announced the initiation of enrollment of children as young as 6 years old in the company's ongoing Phase 2 study of palovarotene for the treatment of fibrodysplasia ossificans progressiva (FOP).

26 Aug 2015

UA professor uses NSF grant to develop 3-D-printed biodegradable polymer scaffolds

Laboratory-engineered noses, jaws and ears. The stuff science fiction is made of is coming soon from a University of Akron lab. With a $390,000 NSF grant, Matthew Becker, UA professor of polymer science and biomedical engineering, is developing 3-D-printed biodegradable polymer scaffolds, the frameworks within which bone will grow, with the hope of changing the face of craniofacial reconstruction.

25 Aug 2015

Gerard E. Francisco to be honored with AAPM&R Distinguished Member Award

Gerard E. Francisco, M.D., chairman of physical medicine and rehabilitation at The University of Texas Health Science Center at Houston Medical School and chief medical officer at TIRR Memorial Hermann, will be recognized at the annual meeting of the American Academy of Physical Medicine and Rehabilitation Oct. 1 - 4 in Boston.

25 Aug 2015

SI-BONE announces publication of results from INSITE and SIFI studies

SI-BONE, Inc., a medical device company that pioneered the use of the iFuse Implant System, a minimally invasive surgical (MIS) device indicated for fusion for certain disorders of the sacroiliac (SI) joint, announced the publication of one-year results from two separate prospective multicenter clinical trials as well as the publication of a systematic review of 18 MIS SI joint fusion studies.

24 Aug 2015

High blood sugar may reduce positive effects of exercise on bone health in diabetic patients

Diabetes, which now affects almost 30 million Americans, can cause serious health complications, including heart disease, blindness, kidney failure and lower-extremity amputations.

24 Aug 2015

Bone News and Research

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Appropriate pre-surgical physical therapy can help joint replacement patients recover faster

Imetelstat drug shows promise in treating patients with myelofibrosis

Researchers perform first focused ultrasound treatments in the U.S. for dyskinesia

Researchers discover that vitamin D may play significant role in preventing AMD among women

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Study: Knee or hip replacement surgery may increase heart attack risk

Scientists discover the oldest case of leukemia in prehistoric female skeleton

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Soligenix obtains additional funding from NIAID to advance development of OrbeShield for GI ARS treatment

Centenary Institute develops new therapeutic approach to prevent GVHD in blood cancer patients

Novartis receives FDA approval for expanded use of Promacta for younger children with rare blood disorder

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

Amedica announces release of Valeo II LL interbody fusion device

Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

UA professor uses NSF grant to develop 3-D-printed biodegradable polymer scaffolds

Gerard E. Francisco to be honored with AAPM&R Distinguished Member Award

SI-BONE announces publication of results from INSITE and SIFI studies

High blood sugar may reduce positive effects of exercise on bone health in diabetic patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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