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Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

Study reveals vitamin B12 as inhibitor of key enzyme in hereditary Parkinson's disease

Iban Ubarretxena, an Ikerbasque Researcher and Director of the Biofisika Institute, participates in a piece of research that has enabled new inhibitors to be identified and which could be used to develop drugs to combat Parkinson's.

3 Apr 2019

Study reveals a revolutionary way to treat eye injuries, prevent blindness

New research led by scientists at Newcastle University, UK reveals a potential revolutionary way to treat eye injuries and prevent blindness - by softening the tissue hosting the stem cells which then helps repair wounds, inside the body.

3 Apr 2019

Molecular biologists develop pipeline to create and screen new lantibiotic peptides

Nature has provided us with lots of antimicrobials. However, given the rapid increase of antimicrobial resistance, there is a need for the development of new-to-nature antibiotics. Lantibiotics are an interesting option.

3 Apr 2019

Tobacco use causes precancerous cells to 'fertilize' nearby cells with cancerous changes

Tobacco use causes a field of precancerous cells, increasing the risk of developing head & neck cancer. But exactly how this precancerous field influences cancer has been often overlooked.

2 Apr 2019

Study finds gene variant which causes hairlessness in dogs

Hairlessness in dogs can be the result of deliberate breeding or, in certain breeds, a defect. A recent study completed at the University of Helsinki describes a gene variant in the SGK3 gene, which causes hairlessness in Scottish Deerhounds.

2 Apr 2019

Gut microbiota can help predict occurrence of colorectal cancer

Gut microbiota - the population of microbes that live in our intestine - can be used to predict the occurrence of colorectal cancer, the second most common type of cancer in women and the third in men.

1 Apr 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Woman who does not feel pain

A woman has been identified by doctors to be able to withstand pain. Surgeons were surprised to encounter her when they noticed that she made a completely painless recovery after a surgery.

28 Mar 2019

Producing human protein in CHO-cells can eliminate the need for blood donors

Alpha-1-antitrypsin is a protein produced by the liver. The protein gets secreted to the blood stream, where it circulates the body to protect the lungs.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

VCU researchers home in on microRNA processing for new cancer therapies

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs.

26 Mar 2019

BU researchers identify biomarker and possible new therapy for melanoma

Researchers have identified a biomarker and a possible new therapy for melanoma.

26 Mar 2019

SupaPore 16FPW microfiltration system improves enzyme production

Amazon Filters reports on how a leading Animal Healthcare company has made significant time and cost savings through implementation of a SupaPore 16FPW microfiltration system for bioburden control on its 100m3 batch production of an enzyme added to chicken feed.

From Amazon Filters Ltd. 25 Mar 2019

Immune system errors linked to development of childhood leukemia

Genetic mutations that drive the development of a common type of childhood leukemia can be traced back to errors by the immune system during the production of antibodies.

25 Mar 2019

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Scientists at Winship Cancer Institute of Emory University, Children's Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells' stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants.

25 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019