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Scientists develop and validate rapid point-of-care HCV assay

One of the major challenges identified by the WHO in efforts to eradicate the hepatitis C virus (HCV) is the diagnosis of chronic cases that are generally asymptomatic.

10 Apr 2018

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans.

10 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

Experts explore how degenerative processes impair the body's detoxification system

A poor diet and other risk factors can result in liver disease. This important metabolic organ can become fatty and inflamed. In the long term, this may result in irreversible and life-threatening organ damage (cirrhosis of the liver or 'shrunken liver').

9 Apr 2018

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

The microbiome is the collection of microorganisms that colonize the human body. Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the gut and cirrhosis, and how microbiome analysis can be used to predict the risk of cirrhosis-associated hospitalizations.

7 Apr 2018

Largest genomic analysis supports additional classification of tumors

University of North Carolina Lineberger Comprehensive Cancer Center researchers are reporting the concluding findings from a major analysis of nearly 10,000 different tumor samples that focused on identifying similarities between cancers based on changes in their genes, and the way their genes are expressed.

6 Apr 2018

Researchers study how often healthcare providers prescribe anticholinergics for older adults

Anticholinergics are a class of medications that are often prescribed for allergies, lung disease, and urinary incontinence. They also often can increase health risks for older adults.

5 Apr 2018

NEOMED professor awarded $2.5 million NIH grant for atherosclerosis research

Northeast Ohio Medical University researcher and professor of integrative medical sciences, Yanqiao Zhang, M.D., has received a five-year, $2.5 million grant from the National Heart, Lung, and Blood Institute, National Institutes of Health, to study the role of hepatic transcription factors in lipid regulation, lipoprotein metabolism, and atherosclerosis, the most common form of cardiovascular disease.

4 Apr 2018

The effects of obesity can be seen in children as young as eight

Obesity may adversely affect liver health in children as young as 8 years old, according to a new study led by researchers at Columbia University Medical Center.

4 Apr 2018

Obesity may have negative impact on liver health in children as young as 8 years old

A new study published today in The Journal of Pediatrics is the first to show that weight gain may have a negative impact on liver health in children as young as 8 years old. The study found that bigger waist circumference at age 3 raises the likelihood that by age 8, children will have markers for nonalcoholic fatty liver disease.

4 Apr 2018

Resistance exercise may improve indicators of type 2 diabetes, study suggests

A new study suggests that resistance exercise may improve indicators of type 2 diabetes by increasing expression of a protein that regulates blood sugar (glucose) absorption in the body.

3 Apr 2018

Lipodystrophy: The Importance of Awareness

An interview with Rebecca Sanders, Lipodystrophy UK co-founder, discussing the importance of awareness campaigns for patients and society at large.

3 Apr 2018

Scientists develop futuristic gene therapy for liver cancer

Genetically engineered human T cells that are effective at fighting liver cancer in mice may one day help patients fight liver cancer, say researchers.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

New review explores potentially safer therapies for treating chronic abdominal pain

An estimated 2 million people in the U.S. are addicted to prescription opioids- powerful doctor-prescribed medications for chronic or severe pain. The drugs are commonly prescribed to treat gastrointestinal pain caused by conditions such as Crohn's disease and irritable bowel syndrome (IBS), raising the risk of addiction among this population.

29 Mar 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

New insights into breast implant-associated anaplastic large-cell lymphoma

For the past seven years, the U.S. Food and Drug Administration has reported on cases of a type of lymphoma associated with breast implants.

28 Mar 2018

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Mothers with mitochondrial DNA mutations often give birth to children who face incurable and fatal illnesses. But a much-studied form of mitochondrial replacement could prevent the transmission of such diseases from mothers to children, researchers say.

28 Mar 2018

Alcohol-related liver cancer may have poor prognosis than other types

A new study indicates that patients with alcohol-related liver cancer often do not live as long as patients with liver cancer that is not associated with alcohol consumption, mainly due to diagnoses at later stages.

28 Mar 2018

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

Liver News and Research

Scientists develop and validate rapid point-of-care HCV assay

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Removal of single mitochondrial protein leads to severe inflammation

Experts explore how degenerative processes impair the body's detoxification system

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

Largest genomic analysis supports additional classification of tumors

Researchers study how often healthcare providers prescribe anticholinergics for older adults

NEOMED professor awarded $2.5 million NIH grant for atherosclerosis research

The effects of obesity can be seen in children as young as eight

Obesity may have negative impact on liver health in children as young as 8 years old

Resistance exercise may improve indicators of type 2 diabetes, study suggests

Lipodystrophy: The Importance of Awareness

Scientists develop futuristic gene therapy for liver cancer

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

New review explores potentially safer therapies for treating chronic abdominal pain

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

New insights into breast implant-associated anaplastic large-cell lymphoma

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Alcohol-related liver cancer may have poor prognosis than other types

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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