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Change in mental status or falls may be misinterpreted as infection in nursing homes

There is a widespread belief that a change in the mental status or an increase in falls in a nursing home resident may indicate an underlying infection.

9 Dec 2020

Henry Ford Health System is first in the U.S. to perform a procedure using CG-100 intraluminal device

Henry Ford Health System is the first in the country to perform a procedure using the CG-100™ intraluminal device, which is temporarily inserted into the gastrointestinal tract and designed to reduce diverting stoma rates, and the need for an ostomy bag, in patients undergoing gastrointestinal resection procedures due to colorectal cancer treatment.

9 Dec 2020

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Older patients with hormone receptor-positive breast cancer who did not receive radiation therapy after breast-conserving surgery had higher rates of local recurrence but similar 10-year survival rates when compared to patients who received postoperative radiation therapy, according to updated 10-year data from the PRIME II study, presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Circulating tumor cell dynamics linked with overall survival in patients with metastatic breast cancer

Early circulating tumor cell dynamics were associated with overall survival in patients with metastatic breast cancer, according to a meta-analysis presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema, and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Mastectomy and reconstructive surgery may increase risk of becoming persistent drug users

Women who receive mastectomy and reconstructive surgery as part of breast cancer treatment may face the risk of developing persistent use of opioids and sedative-hypnotic drugs, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Breast cancer survivors less likely to get pregnant than the general population

A large meta-analysis of breast cancer survivors of childbearing age indicated that they are less likely than the general public to get pregnant, and they face higher risk of certain complications such as preterm labor.

9 Dec 2020

Study confirms inequalities in drinking water arsenic exposure across U.S. populations

A new national study of public water systems found that arsenic levels were not uniform across the U.S., even after implementation of the latest national regulatory standard.

9 Dec 2020

Depressed children, teenagers have higher risk of premature death and wide range of diseases

Depressed children and teenagers have an increased risk of suffering from premature death and a wide range of illnesses later in life.

9 Dec 2020

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

A recent study by US researchers, currently available on the medRxiv preprint server, evaluated several cell-based assays that are under validation for determining correlates of protection in individuals with symptomatic coronavirus disease (COVID-19) and vaccine studies – and demonstrated their high concordance with both live and pseudotyped virions.

9 Dec 2020

Measuring a tau fragment in plasma can help predict future cognitive decline in elderly people

Today, a clinician can order a blood test to check a patient's cholesterol or hemoglobin A1c levels -- biomarkers that help predict an individual's risk of cardiovascular disease or diabetes, respectively. But despite decades of advances in the understanding of Alzheimer's disease (AD), a blood test for predicting its risk remains elusive.

9 Dec 2020

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

The University of Louisville has received funding from the U.S. Department of Defense (DoD) to develop a nasal spray to prevent serious viral respiratory infections such as COVID-19 using Q-Griffithsin, a drug compound developed and co-owned by UofL.

9 Dec 2020

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

After a median follow-up of 5.1 years, among women with lymph node-positive early-stage breast cancer and a recurrence score of 25 or lower who received adjuvant endocrine therapy with or without chemotherapy, postmenopausal patients had no added benefit from chemotherapy, while premenopausal patients who received chemotherapy had improved invasive disease-free survival (IDFS) and an early indication of improved overall survival (OS), according to data from the SWOG S1007 RxPONDER clinical trial presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Tomatoes could become a new, natural source of Parkinson's disease drug

Scientists have produced a tomato enriched in the Parkinson's disease drug L-DOPA in what could become a new, affordable source of one of the world's essential medicines.

9 Dec 2020

As more red states legalize marijuana, some officials try to nip it in the bud

With his state reeling amid one of the worst COVID-19 outbreaks in the nation, the last thing South Dakota Speaker of the House Steven Haugaard wants to be dealing with during the upcoming legislative session is marijuana. But the state's voters haven't left the Republican much choice.

9 Dec 2020

It’s time to scare people about COVID

I still remember exactly where I was sitting decades ago, during the short film shown in class: For a few painful minutes, we watched a woman talking mechanically, raspily through a hole in her throat, pausing occasionally to gasp for air.

9 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Compared to chimpanzees, our closest evolutionary cousins, humans are particularly prone to developing advanced carcinomas -- the type of tumors that include prostate, breast, lung and colorectal cancers -- even in the absence of known risk factors, such as genetic predisposition or tobacco use.

9 Dec 2020

Study reveals new biomarker for amyotrophic lateral sclerosis

ALS is a fatal neurodegenerative disease causing a rapid loss of motor function, which usually results in a serious condition with early death within a few years.

9 Dec 2020

Research News and Research

Change in mental status or falls may be misinterpreted as infection in nursing homes

Henry Ford Health System is first in the U.S. to perform a procedure using CG-100 intraluminal device

Omitting postoperative radiation therapy did not compromise survival for older HR-positive breast cancer patients

Circulating tumor cell dynamics linked with overall survival in patients with metastatic breast cancer

Symptom under-recognition may be common in breast cancer patients treated with radiotherapy

Mastectomy and reconstructive surgery may increase risk of becoming persistent drug users

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Breast cancer survivors less likely to get pregnant than the general population

Study confirms inequalities in drinking water arsenic exposure across U.S. populations

Depressed children, teenagers have higher risk of premature death and wide range of diseases

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

Measuring a tau fragment in plasma can help predict future cognitive decline in elderly people

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

Study shows association between chemotherapy benefit and menopausal status in breast cancer patients

Tomatoes could become a new, natural source of Parkinson's disease drug

As more red states legalize marijuana, some officials try to nip it in the bud

It’s time to scare people about COVID

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Study reveals new biomarker for amyotrophic lateral sclerosis

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