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U.S. Court upholds validity of Eli Lilly's Gemzar compound patent

Eli Lilly and Company today announced that the U.S. District Court for the Southern District of Indiana has upheld the validity of the company's compound patent on Gemzar® (gemcitabine HCl for injection). This decision maintains Lilly's U.S. exclusivity for Gemzar through November 15, 2010.

2 Apr 2010

SBRT effective in primary tumor control, study finds

Many of the world's leading radiation oncologists are employing the unique capabilities of SBRT to treat a variety of cancers that often have defied conventional radiation therapy techniques. A multitude of studies evaluating SBRT are ongoing and investigators are publishing articles that demonstrate the effectiveness of this technique. Two studies led by renowned radiation oncologists were conducted at centers that use Elekta SBRT technology, and their results were published recently.

From Elekta 2 Apr 2010

Multidisciplinary approach holds promise for treating patients with spinal cord injuries

Although new developments in the management of spinal cord injuries are on the horizon, any eventual cure for the condition is more likely to involve a multidisciplinary approach, drawing from expertise in several fields, according to a review article published in the April 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons.

2 Apr 2010

Wireless healthcare system could reduce treatment costs and improve quality of life for diabetic patients

Online communities could easily be used to offer people with chronic illnesses, such as diabetes , wireless healthcare services via mobile phones and the internet. The approach, outlined in the International Journal of Networking and Virtual Organisations, would reduce healthcare costs and empower many patients to manage their condition more effectively.

2 Apr 2010

DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

A new study reveals an exciting potential benefit of the rapidly accumulating databases of health care information, the ability to make unprecedented links between genomic data and clinical medicine. The research, published by Cell Press in the April issue of the American Journal of Human Genetics, supports the idea that large scale DNA databanks linked to electronic medical record (EMR) systems provide a valuable platform for discovering, assessing and validating associations between genes and diseases.

2 Apr 2010

SwitchGear Genomics introduces GoClone miRNA research tool

SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the launch of a unique research tool for screening for miRNA function in living cells. The new SwitchGear GoClone™ miRNA target sets utilize experimentally-validated luciferase reporter vectors to accurately quantify human 3'UTR activity in response to a number of relevant miRNAs.

2 Apr 2010

Study reveals less invasive procedure beneficial for patients with sufficient lung function

Research published in the April edition of the Journal of Thoracic Oncology sought to compare the outcomes of a sleeve lobectomy and a pneumonectomy procedure, in order to determine which is a more acceptable standard treatment for patients with non-small cell lung cancer.

2 Apr 2010

Microbes in polluted groundwater have simple genetic structures that help them overcome environmental stress

Microorganisms can indeed live in extreme environments, but the ones that do are highly adapted to survive and little else, according to a collaboration that includes Department of Energy's Oak Ridge National Laboratory and Joint Genome Institute (JGI) and the University of Oklahoma.

2 Apr 2010

Study promises new combination cancer therapy for drug resistance

Results reported in the April 2nd issue of the journal Cell, a Cell Press publication, reveal a new source for the drug resistance that crops up all too often and quickly in the tumors of cancer patients undergoing therapy.

2 Apr 2010

Hamamatsu launches FDSS/uCELL imaging plate reader for kinetic cell-based assay development

Hamamatsu has announced the release of the FDSS/uCELL, an affordable new imaging plate reader for kinetic cell-based assay development, including GPCR and ion channel research. The uCELL ("micro cell") offers a cost-effective way for biotechnology companies, research institutes, and clinical research organizations to introduce the highly reliable and advanced Hamamatsu FDSS (Functional Drug Screening System) technology to their daily operations.

2 Apr 2010

Sunshine vitamin cures common health problems

What do obesity, heart disease, depression, diabetes, and fibromyalgia have in common? The answer is vitamin D deficiency. More than 200 million Americans lack this essential vitamin and as a result suffer from a host of daily annoyances, chronic conditions, and even life-threatening illnesses.

2 Apr 2010

Study finds potential role of NGF in islet transplantation

Islet transplantation is a promising treatment for type 1 diabetes mellitus. The promotion of angiogenesis is an important endeavor to prevent islet graft failure. Endothelial precursor cells (EPCs), a heterogeneous group originating in the hematopoietic compartment of bone marrow, have an important role in the angiogenesis of adult tissues.

2 Apr 2010

Scientists create genetic map to identify mechanism behind heart abnormalities

Though heart disease is a major cause of disability and death, very little is understood about its genetic underpinnings. Recently, an international team of investigators at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Sanford-Burnham Medical Research Institute (Sanford-Burnham) and other organizations shed new light on the subject.

2 Apr 2010

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

The "cradle" of new neurons in the adult brain is well known. It is what is called the subventricular zone, a tissue structure lining the lateral ventricles. This is where neural or brain stem cells reside, which are responsible for generating new neurons if needed. For many years now, the subventricular zone has been suspected to be the origin of specific malignant brain tumors called gliomas, the most deadly type of which is glioblastoma.

2 Apr 2010

UK NICE recommends Eli Lilly's ALIMTA as maintenance therapy for nonsquamous NSCLC

Eli Lilly and Company announced today that its chemotherapy ALIMTA® (pemetrexed for injection) received a positive "Final Appraisal Determination" from the United Kingdom's National Institute for Health and Clinical Excellence (NICE).

2 Apr 2010

Gene therapy improve survival rates among heart attack patients

Gene therapy could be an effective way to improve survival rates among heart attack patients, new research funded by the British Heart Foundation (BHF) suggests. Academics at the University of Bristol found that boosting levels of a natural growth factor in the heart could help the muscle to recover after a heart attack. The death rate from a heart attack was halved in mice that received the treatment.

1 Apr 2010

Innovative drug design wins medical research prize

The development of a new way to treat iron overload disease has won the 2010 Sir Zelman Cowen Universities Fund Prize for Medical Research.

1 Apr 2010

Protein vaccines for needle-free immunization through the skin

Most immunizations currently involve an injection in the arm. In the future, vaccination may be accomplished without the unpleasant jab of a needle: a team led by Victor C. Yang at the University of Michigan (USA) has developed a method by which vaccines can pass directly through the skin without a needle. As the researchers report in the journal Angewandte Chemie, merely linking a special short peptide molecule to the vaccine, which can then be administered in the form of a patch, will do the job.

1 Apr 2010

FDA clears Sysmex America's XT-4000i Automated Hematology Analyzer

Sysmex America, Inc., a leading medical diagnostic instrument manufacturer and information systems developer, today announced that its Sysmex XT-4000i™ Automated Hematology Analyzer has been cleared by the United States Food and Drug Administration (FDA).

From Sysmex America, Inc. 1 Apr 2010

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

ImmunoCellular Therapeutics announced today that it has filed its Annual Report with the Securities and Exchange Commission for the period ended December 31, 2009 on Form 10-K.

1 Apr 2010

Cell News and Research

U.S. Court upholds validity of Eli Lilly's Gemzar compound patent

SBRT effective in primary tumor control, study finds

Multidisciplinary approach holds promise for treating patients with spinal cord injuries

Wireless healthcare system could reduce treatment costs and improve quality of life for diabetic patients

DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

SwitchGear Genomics introduces GoClone miRNA research tool

Study reveals less invasive procedure beneficial for patients with sufficient lung function

Microbes in polluted groundwater have simple genetic structures that help them overcome environmental stress

Study promises new combination cancer therapy for drug resistance

Hamamatsu launches FDSS/uCELL imaging plate reader for kinetic cell-based assay development

Sunshine vitamin cures common health problems

Study finds potential role of NGF in islet transplantation

Scientists create genetic map to identify mechanism behind heart abnormalities

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

UK NICE recommends Eli Lilly's ALIMTA as maintenance therapy for nonsquamous NSCLC

Gene therapy improve survival rates among heart attack patients

Innovative drug design wins medical research prize

Protein vaccines for needle-free immunization through the skin

FDA clears Sysmex America's XT-4000i Automated Hematology Analyzer

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

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