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NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

A clinical trial of an experimental drug designed to treat cravings associated with opioid use disorder has begun in the National Institutes of Health Clinical Center.

22 Mar 2019

New device approved by FDA for treating patients with moderate-to-severe heart failure

The U.S. Food and Drug Administration today approved the Optimizer Smart system for treating patients with chronic, moderate-to-severe heart failure who are not suited for treatment with other heart failure devices such as cardiac resynchronization therapy to restore a normal timing pattern of the heartbeat.

22 Mar 2019

Air Force develops genetic test to predict mental performance

A research psychologist at the Air Force Research Laboratory can predict your mental performance from a cheek swab or blood sample.

22 Mar 2019

High-fructose corn syrup fuels growth of colon tumors in mice

Consuming the equivalent of one can of soda per day caused mice predisposed to colon cancer to develop larger tumors, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

22 Mar 2019

New combination treatment shows promise for common brain tumor in children

A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models.

22 Mar 2019

Novel breath test could pave new way to non-invasively measure gut health

Small children may one day avoid invasive, painful and often traumatic oesophageal tube-testing for gut damage and coeliac disease with a new method of simply blowing into a glass tube to provide effective diagnoses.

20 Mar 2019

CRISPR/Cas libraries could revolutionize drug discovery

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

20 Mar 2019

Umass Amherst food scientist honored with 2019 Young Scientist Research Award

Guodong Zhang, assistant professor of food science at the University of Massachusetts Amherst, is being honored with the 2019 Young Scientist Research Award from the American Oil Chemists' Society.

20 Mar 2019

Age-related changes to gut microbiome have adverse impact on vascular health, study shows

Why do blood vessels naturally stiffen and degrade as we age, boosting cardiovascular disease risk? New University of Colorado Boulder research has identified a surprising new culprit--and it lives in your gut.

20 Mar 2019

Roundworm study suggests alternatives for treatment of schizophrenia

A group of Brazilian scientists have long conducted experiments with roundworms to investigate the role of schizophrenia-linked genes in patients' response to antipsychotic drugs. The results obtained thus far point to new ways of understanding resistance to certain classes of medication.

20 Mar 2019

Enzyme inhibitor stops inflammation and neurodevelopmental disorders in mouse models

Work published this week in the journal Proceedings of the National Academy of Sciences shows that an enzyme inhibitor developed by Professor Bruce Hammock and colleagues at UC Davis reduced inflammation in the brains of mice born to mothers with maternal immune activation.

20 Mar 2019

Study brings clarity about milk intake for children with Duarte galactosemia

Milk can be lethal to babies with classic galactosemia, a rare genetic disorder that severely impairs the body's ability to process a milk sugar known as galactose and is associated with a host of neurodevelopmental issues.

19 Mar 2019

A new option for reducing LDL cholesterol in patients at high risk for heart attack, stroke

Patients at high risk for a heart attack or stroke who took an investigational drug in addition to a statin had significantly lower LDL, or "bad" cholesterol, after 12 weeks compared to similar patients who took a placebo in addition to statin therapy, according to research presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Researchers at the George Washington University Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.

15 Mar 2019

Study shows how cell death can be triggered by a mitochondrial enzyme

Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria.

15 Mar 2019

Natural speed limit on DNA replication sets pace for life's first steps

Fruit flies make for stingy mothers, imparting only a portion of the genetic building blocks their offspring need to survive. The rest must be produced by the fertilized egg in its first few steps of growth.

15 Mar 2019

Success for new cholesterol-lowering drug

A new, oral drug that effectively lowers LDL or "bad" cholesterol, looks set for clinical approval.

14 Mar 2019

Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women's elevated risk of developing breast cancer after menopause.

14 Mar 2019

New discovery of how organs form helps scientists to develop treatments for diabetes, cancer

In a new study, researchers at the University of Copenhagen show that the development of a certain type of immature stem cells - also known as progenitor cells - depends on the quantity of a special protein and interaction with other cells in the body.

14 Mar 2019

Enzyme News and Research

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

New device approved by FDA for treating patients with moderate-to-severe heart failure

Air Force develops genetic test to predict mental performance

High-fructose corn syrup fuels growth of colon tumors in mice

New combination treatment shows promise for common brain tumor in children

Novel breath test could pave new way to non-invasively measure gut health

CRISPR/Cas libraries could revolutionize drug discovery

Umass Amherst food scientist honored with 2019 Young Scientist Research Award

Age-related changes to gut microbiome have adverse impact on vascular health, study shows

Roundworm study suggests alternatives for treatment of schizophrenia

Enzyme inhibitor stops inflammation and neurodevelopmental disorders in mouse models

Study brings clarity about milk intake for children with Duarte galactosemia

A new option for reducing LDL cholesterol in patients at high risk for heart attack, stroke

Promising gene therapy could restore vision in humans

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Study shows how cell death can be triggered by a mitochondrial enzyme

Natural speed limit on DNA replication sets pace for life's first steps

Success for new cholesterol-lowering drug

Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

New discovery of how organs form helps scientists to develop treatments for diabetes, cancer

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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