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Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Algeta ASA has announced that with the results of the BC1-04 study reported today it has completed its comprehensive phase II clinical program evaluating Alpharadin (radium-223) as a new treatment for bone metastases in patients with hormone-refractory prostate cancer (HRPC).

15 Jan 2009

Novel low-cost immunotherapy for cancer cells

Molecules of sugar sitting on the surface of cancer cells are keys to the development of a new vaccine aimed at both treating and stopping the spread of certain types of cancers called carcinomas, which include prostate, breast, ovarian and lung, among others.

8 Jan 2009

Narrow-band imaging comparable to white light colonoscopy in differentiating colorectal polyps

Researchers from Yale University School of Medicine compared narrow-band imaging (NBI) without high magnification to standard white light colonoscopy in differentiating colorectal polyps during real-time colonoscopy and found that NBI was not more accurate than white light colonoscopy.

15 Dec 2008

Magnetic resonance imaging alternated with mammography may be best for high-risk women

Magnetic resonance imaging (MRI) alternated with mammography at six-month intervals can detect breast cancers not identified by mammography alone, a research team from The University of Texas M. D. Anderson Cancer Center will report at the 31st at the CRTC-AACR San Antonio Breast Cancer Symposium.

14 Dec 2008

Stem cells derived from bone marrow may offer novel therapeutic option for epidermolysis bullosa

Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology.

5 Dec 2008

Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer

A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene.

3 Dec 2008

Analysis of tissue biomarkers expressed in ovarian cancer samples

Although ovarian cancer is not the most common gynecologic cancer in women, the disease contributes a substantial burden of mortality in part because symptoms are nonspecific and the disease presents late in its course.

1 Dec 2008

Scribble protein found to be an important regulator of breast cancer

In breast tissue, cells lining the breast's ducts have a certain shape that is required to maintain both organ structure and function.

26 Nov 2008

Mammogram most effective 12 months after radiation

Breast cancer patients who receive breast-conserving therapy and radiation do not need a follow-up mammogram until 12 months after radiation, despite current guidelines that recommend follow-up mammograms at between six and 12 months after radiation, according to a November 15 study in the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

25 Nov 2008

Scientists develop peptide that converts Bcl-2 protein from a cancer cell's friend to a foe

If you're a cancer cell, you want a protein called Bcl-2 on your side because it decides if you live or die.

25 Nov 2008

Burning incense ups the risk of respiratory tract cancers

New research is suggesting that using incense for long periods could increase the risk of developing cancers of the respiratory tract.

26 Aug 2008

Long term use of incense increases the risk of developing cancers of the respiratory tract

Long term use of incense increases the risk of developing cancers of the respiratory tract, according to a new study. The new analysis, which the authors say is the first prospective investigation of incense and cancer risk, appears in the October 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society.

25 Aug 2008

Sniffing out skin cancer by smell

According to researchers in the U.S. the smell skin gives off could indicate the presence of skin cancers. They say cancers such as basal cell carcinomas can be identified by the odour on the skin.

25 Aug 2008

Researchers find better way to distinguish melanoma from some benign moles

University of Rochester Medical Center researchers found a new protein produced excessively in malignant melanoma, a discovery that is particularly relevant as skin cancer rates climb dramatically among young women.

17 Jul 2008

Treating rare breast cancer with radiation therapy may lower recurrence rate

Patients with a rare type of breast cancer may benefit from receiving radiation therapy in addition to surgery to prevent recurrence, according to a study in the July issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

13 Jul 2008

Discovery of gene mechanism could lead to new therapeutic strategies to fight metastatic disease

Virginia Commonwealth University and VCU Massey Cancer Center researchers have uncovered how a gene, melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24), induces a bystander effect that kills cancer cells not directly receiving mda-7/IL-24 without harming healthy ones, a discovery that could lead to new therapeutic strategies to fight metastatic disease.

1 Jul 2008

Dogs successfully detect ovarian cancer through scent

Ground-breaking research in the June issue of Integrative Cancer Therapies published by SAGE explored whether ovarian cancer has a scent different from other cancers and whether working dogs could be taught to distinguish it in its different stages.

26 Jun 2008

Cetuximab and chemotherapy combination proves safe, effective for head and neck cancer patients

Patients treated for locally advanced head and neck cancer may respond better to treatment with the addition of cetuximab to chemotherapy, according to a University of Pittsburgh Cancer Institute (UPCI) phase II study. The results will be presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago as an oral presentation.

2 Jun 2008

Whole-organ genomic survey depicts journey from normal to malignant cell

Whole-organ maps that superimpose genetic information over the terrain of cancerous bladders chart the molecular journey from normal cell to invasive cancer, an international research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports online at the journal Laboratory Investigation.

5 May 2008

Epidermal growth factor receptor protects cancer cells from starving

A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism, researchers at The University of Texas M. D. Anderson Cancer Center report in the May 5 issue of Cancer Cell.