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Macrophages play a central role in intestinal cell renewal, study reveals

A research team from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration.

10 Oct 2023

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

9 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University.

4 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

Early feeding practices key to shaping lifelong oral microbiome

Research delves into the little-explored world of the infant oral microbiome, examining how early nutrition and environmental factors shape it. With implications for lifelong health, the research aims to guide future health recommendations, emphasizing the need for more longitudinal studies and advanced sequencing techniques.

26 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells - each one complete with an identical set of genes - a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Researchers develop new method to deliver strong antibiotic drugs more safely

Antibiotic resistant bacteria are a threat to human lives, and yet the development of new drugs to treat bacterial infections is slow.

25 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Brazilian fruits positively impact gut health and chronic disease prevention

The influence of Brazilian native fruits and their by-products on human intestinal microbiota.

21 Sep 2023

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Researchers evaluated sensitivity to immune checkpoint blockade (ICB) therapy.

20 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

MGI Tech Singapore Pte, Ltd. ("MGI"), a company committed to building core tools and technology to lead life science, recently entered a research partnership with National Cancer Centre Singapore ("NCCS") to facilitate comprehensive, multi-dimensional genomic profiling of Asian-prevalent cancers using MGI's core DNBSEQ™ technology.

From MGI 18 Sep 2023

How does the APOE4 gene play both hero and villain in your health risks?

The study reveals that APOE4, a genetic risk factor for Alzheimer's Disease and cardiovascular diseases, has complex effects on mortality risk. While APOE4 carriers with higher AD neuropathology have increased mortality risk, those with low neuropathology had a reduced risk of certain cancers, warranting further research into this genetic factor's diverse impact on health outcomes.

14 Sep 2023

Colon News and Research

Macrophages play a central role in intestinal cell renewal, study reveals

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Wood cookstove use linked to gastric cancer risk

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

Research opens the door for better use of people's own immune system T cells to fight cancer

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Early feeding practices key to shaping lifelong oral microbiome

Gene-silencer study could pave the way for novel cancer therapeutics

Researchers develop new method to deliver strong antibiotic drugs more safely

Exercise boosts immune defense in Lynch syndrome patients

Brazilian fruits positively impact gut health and chronic disease prevention

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

MGI partners with National Cancer Centre Singapore to undergo comprehensive genomic profiling of Asian-Prevalent cancers

How does the APOE4 gene play both hero and villain in your health risks?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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