Gastrointestinal Tract News and Research

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Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Tulane University's Stryder Meadows, a cell and molecular biology professor, received a $1.7 million grant from the Department of Defense to study how arteriovenous malformations (AVM), which are defects in arteries, veins and capillaries, form Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that affects about 1 in 5,000 people.

14 Nov 2017

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

The Center for Applied NanoBioscience and Medicine is doing its part to protect the health of astronauts on long-duration missions, including NASA's Journey to Mars.

9 Nov 2017

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

An overabundance of the bacteria Veillonella in the digestive tract may increase pain in patients with sickle cell disease (SCD).

8 Nov 2017

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

8 Nov 2017

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

Extracorporeal shock-wave therapy at low energy levels showed promise as a new treatment for digital ulcers in patients with systemic sclerosis, or scleroderma, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Study points to novel, effective treatment for CKD patients with metabolic acidosis

Patients with chronic kidney disease (CKD) often develop a condition called metabolic acidosis, which is characterized by an imbalance in acid production relative to excretion.

6 Nov 2017

Nicotine alters gut microbiome differently in males and females, mice study shows

Many people who smoke or chew tobacco can't seem to escape nicotine's addictive properties. Studies show that women in particular seem to have a harder time quitting, even with assistance, when compared to men.

3 Nov 2017

Research may explain why gum disease is linked to heart problems

Heart disease and fatty clogs in the arteries go hand in hand. But new evidence suggests the fatty molecules might come not only from what you eat, but from the bacteria in your mouth, report UConn scientists in the 16 August issue of the Journal of Lipid Research.

1 Nov 2017

Gut bacteria could hold clues to risk of developing PTSD after traumatic event

The bacteria in your gut could hold clues to whether or not you will develop posttraumatic stress disorder (PTSD) after experiencing a traumatic event.

25 Oct 2017

New studies provide insight into treatments for Barrett's esophagus

The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).

6 Oct 2017

Study findings provide new insight into inflammatory bowel disease

Findings from a study into Crohn's disease, led by William G. Kerr, Ph.D., of SUNY Upstate Medical University, and his collaborators at the Erasmus Medical Center in the Netherlands, provide the first evidence that patients with debilitating inflammatory bowel disease lack sufficient quantities of a protein that comes from the SHIP1 gene.

6 Oct 2017

Two MSU researchers team up to tackle problem of arsenic poisoning

Two Montana State University researchers in different disciplines have teamed up to tackle the problem of arsenic poisoning, which is estimated by the World Health Organization to affect more than 100 million people worldwide, primarily through tainted drinking water.

4 Oct 2017

Probiotic bacteria can change intestinal flora of patients with colon cancer, study finds

Living lactic acid bacteria, probiotics, can change the intestinal flora of patients with cancer of the colon. These are the findings of a study published in the journal BMJ Open Gastroenterology.

25 Sep 2017

'Small intestinal permeable peptides' improve biopharmaceuticals absorption in digestive tract

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, resulting in a bottleneck for oral administration type biopharmaceutical development.

20 Sep 2017

Caltech researchers develop miniature device for use in ‘smart pills’ to diagnose and treat diseases

Researchers at Caltech have developed a prototype miniature medical device that could ultimately be used in "smart pills" to diagnose and treat diseases.

12 Sep 2017

PolyU researchers uncover new hyper-resistant, hypervirulent superbug

The Partner State Key Laboratory of Chirosciences at the Department of Applied Biology and Chemical Technology of The Hong Kong Polytechnic University discovered a newly emerged superbug, hyper-resistant and hypervirulent Klebsiella pneumoniae, which may cause untreatable and fatal infections in relatively healthy individuals and will pose enormous threat to human health.

31 Aug 2017