Glucagon News and Research

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New discovery could provide opportunity to improve blood glucose control

Many diabetes patients do not only have problems with their insulin, but also with the release of the hormone glucagon. Researchers at Uppsala University have now discovered a regulation mechanism which could provide an opportunity to improve blood glucose control in these patients.

26 Apr 2019

New review on relationship between COPD and Type 2 diabetes

Chronic obstructive pulmonary disease is characterized by a chronic airflow obstruction that is associated with severe global mortality and morbidity.

23 Apr 2019

Older adults with type 1 diabetes have hypoglycemia over an hour a day

Older adults with type 1 diabetes typically have low blood sugar, or hypoglycemia, for more than an hour a day, suggests research to be presented Monday, March 25 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

25 Mar 2019

Diabetes' sworn enemy could also be a protective asset

Montreal research team unravels an adaptive mechanism involved in controlling insulin action, showing that glucagon plays a crucial part in it and can thus be a protective asset.

6 Mar 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019

Human cells can change their original function to battle against diabetes

For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for diabetes patients.

14 Feb 2019

Bariatric surgery changes the way our body senses food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports.

8 Feb 2019

Discovery may lead to new form of treatment for diabetes

Diabetes is caused by damaged or non-existing insulin cells inability to produce insulin, a hormone that is necessary in regulating blood sugar levels. Many diabetes patients take insulin supplements to regulate these levels.

7 Jan 2019

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Atherosclerosis and cardiovascular disease are major complications of HIV infection and cannot currently be treated by antiretroviral treatments.

21 Dec 2018

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

New bacterial species may help fight obesity and metabolic disorders

The MyNewGut project has discovered new bacterial species and strains in healthy people that seem to be effective against obesity, metabolic and mental disorders related to stress and obesity (e.g. depression).

17 Dec 2018

Liraglutide drug associated with lower risk of cardiovascular events

Real world data from a large Nordic study shows that use of liraglutide, a drug for type 2 diabetes, is associated with a lower risk of myocardial infarction, stroke or cardiovascular death.

6 Dec 2018

New strategy for developing cell replacement therapies to combat type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment.

29 Nov 2018

Study examines factors associated with fasting hyperglucagonemia in type 2 diabetes

A new study examined the relationship between fasting hyperglucagonemia -- which can negatively affect glucose metabolism in patients with type 2 diabetes -- and several biochemical and glycemic factors in subjects with T2D or in a nondiabetic control group.

24 Oct 2018

Study shows that one amino acid may produce short-term lowering of glucose levels

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins.

11 Oct 2018

Study investigates effects of glucose-lowering drug in preventing damage to the kidneys

New research presented at the annual meeting of the European Association for the Study of Diabetes and published simultaneously in The Lancet Diabetes & Endocrinology shows how the glucose-lowering drug lixisenatide can slow or prevent damage to the kidneys in macro-albuminuric patients with type 2 diabetes mellitus and cardiovascular disease.

3 Oct 2018

New research sheds light on the causes of diabetes

The main cause of all forms of diabetes is pancreatic beta-cell dysfunction. Beta cells, found in the pancreatic islets, store and release insulin.

14 Sep 2018

Researchers examine Twitter conversations to understand thoughts concerning OpenAPS technology

The diabetes online community is leading grassroots efforts focused on accelerating the development, access and adoption of diabetes-related tools to manage the disease.

11 Sep 2018

OHSU professor conducts clinical trial with artificial pancreas using Xeris' liquid glucagon

Xeris Pharmaceuticals, Inc., a specialty pharmaceutical company leveraging its novel technology platforms to develop and commercialize ready-to-use injectable and infusible drug formulations, announced today that Jessica Castle, M.D., an associate professor of medicine in the OHSU School of Medicine and OHSU Harold Schnitzer Diabetes Health Center in Portland, Oregon, is conducting a clinical trial with a dual-hormone artificial pancreas using Xeris' ready-to-use liquid glucagon to evaluate a new closed-loop algorithm.

17 Aug 2018

Research uncovers miscarriage cause, identifies potential targets for treatment

Tragic miscarriages for a couple have led to a discovery with potentially broad implications for future disease treatments, according to a team of researchers at the University of North Carolina School of Medicine. They identified a previously undiscovered gene mutation underlying hydrops fetalis – a fatal condition to fetuses due to fluid buildup in the space between organs.

16 Aug 2018