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Enterprise Therapeutics doses first subjects in Phase I trial for novel cystic fibrosis therapy ETD001

Enterprise Therapeutics Ltd today announced it has successfully dosed the first subjects in a Phase 1 trial for its novel inhaled cystic fibrosis therapy, ETD001.

14 Jun 2021

Are women more likely to develop long COVID?

Researchers found different groups of symptoms persisting after coronavirus disease 2019 (COVID-19), with fatigue and higher IL-6 levels common in women. About 75% of the patients they treated were women, indicating a link between sex hormones and immune response.

8 Jun 2021

People with many siblings have increased risk of cardiovascular events

First-born children have a lower risk of cardiovascular events such as heart attacks and strokes than brothers and sisters born later, but people who are part of a large family with many siblings have an increased risk of these events, suggests the results of a large population study in Sweden, published in the online journal BMJ Open.

4 Jun 2021

Researchers report how the tobacco and e-cigarette industry capitalized on COVID-19 to promote smoking

Scientific papers suggesting that smokers are less likely to fall ill with covid-19 are being discredited as links to the tobacco industry, reveals an investigation by The BMJ today.

4 Jun 2021

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

3 Jun 2021

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Airway mucus consists of various proteins such as long mucins MUC5AC and MUC5B, both of which contribute greatly to the proper gel-like consistency of this most essential bodily fluid.

3 Jun 2021

Study reveals prevalence of multimorbidity among people using methamphetamine

People who use methamphetamine are more likely to have health conditions, mental illness, and substance use disorders than people who do not use the drug, according to a new study by researchers at the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health.

3 Jun 2021

Researchers are closer to unraveling the mystery of science behind regeneration

Many salamanders can readily regenerate a lost limb, but adult mammals, including humans, cannot. Why this is the case is a scientific mystery that has fascinated observers of the natural world for thousands of years.

3 Jun 2021

Long COVID patients at higher risk of small airway disease

The preprint discussed herein describes the effects of SARS-CoV-2 on lung structure and function in patients with long COVID.

2 Jun 2021

Methamphetamine users more susceptible to have medical, mental, and substance use issues

People who use methamphetamine are nearly twice as likely to have medical multimorbidity, and over three times as likely to have a mental illness.

2 Jun 2021

WVU gets ECHO Superhub designation

The West Virginia Clinical and Translational Science Institute Project ECHO program has been spreading specialty care knowledge across the Mountain State for five years.

1 Jun 2021

Study supports the need for improving early TB diagnosis and care in Irish prisons

Investigators from Trinity College Dublin, the Irish Mycobacteria Reference Laboratory, St James's Hospital, and the Department of Public Health HSE East believe tuberculosis (TB) care in Irish Prisons should be supported, considering the findings of their study which is published today (Tuesday, 1st June, 2021) in the International Journal of Tuberculosis and Lung Disease.

1 Jun 2021

FIRS calls on governments and policymakers to support and promote tobacco cessation services

On World No Tobacco Day (31 May, 2021) the Forum of International Respiratory Societies (FIRS), of which the American College of Chest Physicians® (CHEST) is a founding member, calls on governments and policymakers to make greater political and financial commitments to support and promote tobacco cessation services.

29 May 2021

FDA approves targeted therapy for tumors with KRAS mutations

Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy.

29 May 2021

Study shows CoronaVac to have high seroconversion rate after 40 days

Researchers from the Federal University of Paraná, Brazil, looked into the seroconversion rate after vaccination with the CoronaVac. Using immunoassays, they measured the immunoglobulins (IgG) for anti-nucleocapsid protein (anti-N) antibodies and anti-spike-1 (anti-S1) protein antibodies.

27 May 2021

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

21 May 2021

Monoclonal antibody bamlanivimab reduces hospitalization and death in moderate-to-severe COVID-19

Researchers at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center found that monoclonal antibodies, a COVID-19 treatment administered early after infection, reduce the risk of hospitalization and death by 60 percent in people at high risk of suffering complications from the condition.

20 May 2021

New cardiac rehabilitation intervention improves quality of life in hospitalized heart failure patients

An innovative cardiac rehabilitation intervention started earlier and more custom-tailored to the individual improved physical function, frailty, quality-of-life, and depression in hospitalized heart failure patients, compared to traditional rehabilitation programs.

17 May 2021

Heart Research UK awards grant for a research project investigating how COVID-19 damages blood vessels

University of Dundee project investigating the role of inflammation in blood vessel damage in COVID-19 patients receives grant from Heart Research UK

17 May 2021

Older heart failure patients significantly benefit from tailored cardiac rehab program

Older patients hospitalized with acute heart failure who participated in a novel 12-week physical rehabilitation (rehab) program tailored to address their specific physical impairments had significant gains not only in physical functioning but also quality of life and depression compared with those receiving usual care, regardless of their heart's ejection fraction, according to a new study presented at the American College of Cardiology's 70th Annual Scientific Session.

17 May 2021

Lung Disease News and Research

Enterprise Therapeutics doses first subjects in Phase I trial for novel cystic fibrosis therapy ETD001

Are women more likely to develop long COVID?

People with many siblings have increased risk of cardiovascular events

Researchers report how the tobacco and e-cigarette industry capitalized on COVID-19 to promote smoking

Mast cell activation may underlie inflammation in severe COVID-19

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Study reveals prevalence of multimorbidity among people using methamphetamine

Researchers are closer to unraveling the mystery of science behind regeneration

Long COVID patients at higher risk of small airway disease

Methamphetamine users more susceptible to have medical, mental, and substance use issues

WVU gets ECHO Superhub designation

Study supports the need for improving early TB diagnosis and care in Irish prisons

FIRS calls on governments and policymakers to support and promote tobacco cessation services

FDA approves targeted therapy for tumors with KRAS mutations

Study shows CoronaVac to have high seroconversion rate after 40 days

FDA approves Rybrevant for treating subset of non-small cell lung cancer

Monoclonal antibody bamlanivimab reduces hospitalization and death in moderate-to-severe COVID-19

New cardiac rehabilitation intervention improves quality of life in hospitalized heart failure patients

Heart Research UK awards grant for a research project investigating how COVID-19 damages blood vessels

Older heart failure patients significantly benefit from tailored cardiac rehab program

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