Neurodegenerative Disease News and Research

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Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

University of California, Irvine biologists have developed a new genetically engineered mouse model that, unlike its predecessors, is based on the most common form of Alzheimer's disease.

27 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

Study provides new insights into how signal molecules are transported in the axons

In a new study, researchers from the University of Copenhagen have gained new insights into how signal molecules are transported in some of the longest cells in the nervous system.

17 Apr 2021

Personality trait neuroticism associated with higher risk of Parkinson's disease

New research from the Florida State University College of Medicine has found that the personality trait neuroticism is consistently associated with a higher risk of developing the brain disorder Parkinson's disease.

15 Apr 2021

UCSB professor receives 2021 Potamkin Prize for major contributions to Alzheimer’s research

When UC Santa Barbara neurology professor Kenneth S. Kosik was a newly minted graduate in 1972, with bachelor's and master's degrees in English literature from Case Western University, becoming one of the foremost authorities in the field of Alzheimer's research was probably nowhere on his radar. But that would soon change.

15 Apr 2021

Researchers discover a new way to prevent brain nerve cells from deteriorating after injury

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment after suffering a TBI.

13 Apr 2021

New consortium aims to accelerate development of stem cell-based therapies for Huntington’s disease

The Stem Cells for Huntington's Disease (SC4HD) is a new international consortium created to promote advanced therapy medicinal product (ATMP) through cell transplantation studies on Huntington's Disease.

9 Apr 2021

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

This study builds upon two earlier published studies (Mold et al., 2020, Journal of Alzheimer's Disease Reports) from the same group. The new data, also published in the Journal of Alzheimer's Disease Reports, demonstrate that aluminum is co-located with phosphorylated tau protein, present as tangles within neurons in the brains of early-onset or familial Alzheimer's disease (AD).

9 Apr 2021

Researchers uncover the mysteries of sleep disorders in multiple system atrophy

Multiple system atrophy (MSA) is a neurodegenerative disease with multiple debilitating symptoms. One of them is sleep disorders; however, owing to limited research, little is known about why only some patients are affected, how sleep disorders influence MSA severity, or even how sleep disorders vary across different MSA subtypes.

9 Apr 2021

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Powerful algorithms used by Netflix, Amazon and Facebook can 'predict' the biological language of cancer and neurodegenerative diseases like Alzheimer's, scientists have found.

8 Apr 2021

Parkinson's disease, type 2 diabetes, and cancer share the same pathway, shows study

When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell.

8 Apr 2021

USF wins $44.4 million NIH grant to test whether computerized brain training can prevent dementia

The National Institutes of Health has awarded the University of South Florida total expected funds of $44.4 million over the next five years to study whether computerized brain training exercises can reduce the risk of mild cognitive impairment (MCI), and dementias like Alzheimer's disease, in older adults.

7 Apr 2021

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

The rarity of spinal muscular atrophy (SMA) means that promising new treatments may be tested in only a limited spectrum of patients before approval. Investigators evaluated a newly approved drug, onasemnogene abeparvovec, in a broader spectrum of patients in order to obtain expanded data on its side effects profile.

6 Apr 2021

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.

3 Apr 2021

Signal detection theory can be used to better understand cognitive fatigue

A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue.

1 Apr 2021

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Dr. Simonetta Sipione, GlycoNet Investigator and Professor in the Department of Pharmacology at the University of Alberta, was recently awarded a major five-year grant from the Canadian Institutes of Health Research, worth $1.04 million.

26 Mar 2021

Novel technology may reveal the brain's mysteries

A team of scientists, led by researchers at Northwestern University, Shirley Ryan AbilityLab and the University of Illinois at Chicago (UIC), has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

22 Mar 2021

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers have used a genetic engineering strategy to dramatically reduce levels of tau--a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer's disease--in an animal model of the condition.

21 Mar 2021

Researchers describe a new approach to treating Parkinson's disease

Parkinson's disease is the second most common, age-related, neurodegenerative disease: In Germany alone, about 300,000 people are affected and experience sometimes major limitations to their quality of life.

20 Mar 2021

Neurodegenerative Disease News and Research

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

UCI biologists develop new mouse model to study late-onset Alzheimer's disease

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Study provides new insights into how signal molecules are transported in the axons

Personality trait neuroticism associated with higher risk of Parkinson's disease

UCSB professor receives 2021 Potamkin Prize for major contributions to Alzheimer’s research

Researchers discover a new way to prevent brain nerve cells from deteriorating after injury

New consortium aims to accelerate development of stem cell-based therapies for Huntington’s disease

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

Researchers uncover the mysteries of sleep disorders in multiple system atrophy

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Parkinson's disease, type 2 diabetes, and cancer share the same pathway, shows study

USF wins $44.4 million NIH grant to test whether computerized brain training can prevent dementia

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

Signal detection theory can be used to better understand cognitive fatigue

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Novel technology may reveal the brain's mysteries

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers describe a new approach to treating Parkinson's disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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