Progenitor Cells News and Research

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Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

Unlike the self-repair abilities of our skin, bone and other tissues, which can readily heal and rebuild themselves after injury, evolution has left the mammalian heart with relatively little regenerative capacity.

22 Feb 2017

Study identifies protein in tumor microenvironment that promotes breast cancer spread

To understand what makes breast cancer spread, researchers are looking at where it lives - not just its original home in the breast but its new home where it settles in other organs. What's happening in that metastatic niche where migrated cancer cells are growing?

16 Feb 2017

Scientists discover population of progenitor cells linked to formation of heart’s ventricular chambers

A population of cells in early development may give rise to the ventricular chambers of the heart, but not the atria, according to a study led by researchers from the Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai and published today in Nature Communications.

14 Feb 2017

LMU study shows crucial role of microRNAs in protecting precursors of neurons

Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.

13 Feb 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

New therapy to treat spinal cord injuries shows improvements in motor function

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site shows additional motor function improvement at 6-months and 9-months following treatment with 10 million AST-OPC1.

24 Jan 2017

Researchers move one step closer to regenerating heart wall using stem cells

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers.

12 Jan 2017

Specific gene pathway appears to regulate growth, structure, and organization of cerebral cortex

One of the most significant ways in which the human brain is unique is the size and structure of the cerebral cortex. But what drives the growth of the human cortex, likely the foundation for our unique intellectual abilities?

30 Dec 2016

New class of monocyte cells with strange morphology may cause fibrosis

Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM.

22 Dec 2016

Sirt1 plays key role in regenerating glial progenitor cells after hypoxia-induced brain injury in preemies

Developing brains in newborns have a sizable pool of a certain type of immature progenitor cell that can be expanded and induced to replace cells lost to brain injury.

19 Dec 2016

Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Women with inherited mutations in the BRCA1 or BRCA2 genes are at substantially higher risk of breast cancer. For these women, effective prevention strategies are their best hope to reduce their breast cancer risk.

16 Dec 2016

Alkaloid in ayahuasca beverage triggers neurogenesis in human neural cells

Ayahuasca is a beverage that has been used for centuries by Native South-Americans. Studies suggest that it exhibits anxiolytic and antidepressant effects in humans.

7 Dec 2016

UCLA researchers discover how chronic inflammation increases prostate cancer risk

UCLA researchers have discovered a previously unrecognized type of progenitor cell that, though rare in most regions of the human prostate, is found in uncommonly high numbers in inflamed areas of the gland.

6 Dec 2016

Cedars-Sinai receives $7.3 million grant to test safety of novel cell-based therapy in treating PAH

Researchers from the Cedars-Sinai Heart Institute and the Cedars-Sinai Department of Medicine are expanding their ongoing evaluation of a novel cell-based therapeutic candidate into the area of pulmonary arterial hypertension (PAH).

6 Dec 2016

Study compares cardiac repair potential of three types of stem cells

New research from New Zealand's University of Otago is providing fresh insights into how a patient's adult stem cells could best be used to regenerate their diseased hearts.

29 Nov 2016

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow.

23 Nov 2016

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

A multi-institutional group of researchers, led by investigators at Children's Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.