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Scientists grow transgenic plants to double production of artemisinin for fighting against malaria

Since the ancient times, mankind has used plants to treat diseases. An example is the plant Artemisia annua, used for over 2,000 years in traditional Chinese medicine to treat intermittent fevers.

28 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

Scientists discover potential role for 'jumping genes' in ALS

By inserting an amyotrophic lateral sclerosis (ALS)-linked human gene called TDP-43 into fruit flies, researchers at Stony Brook University and Cold Spring Harbor Laboratory discovered a potential role for 'transposons' in the disease.

24 Mar 2017

TUM scientists show how diabetes damages small blood vessels around the heart

Diabetics have a significantly higher risk of suffering a heart attack. A research team at the Technical University of Munich has now identified one of the causes: Diabetes is associated with the loss of small blood vessels around the heart.

23 Mar 2017

Researchers discover new genes that help prevent prostate and other cancers

New genes which help prevent prostate, skin and breast cancer development in mice have been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators.

20 Mar 2017

Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome

The majority of genes associated with nephrotic syndrome (NS) in humans also play pivotal roles in Drosophila renal function, a conservation of function across species that validates transgenic flies as ideal pre-clinical models to improve understanding of human disease, a Children's National Health System research team reports in a recent issue of Human Molecular Genetics.

17 Mar 2017

Novel nanoengineered retinal prosthesis may help restore eyesight

A team of engineers at the University of California San Diego and La Jolla-based startup Nanovision Biosciences Inc. have developed the nanotechnology and wireless electronics for a new type of retinal prosthesis that brings research a step closer to restoring the ability of neurons in the retina to respond to light.

14 Mar 2017

Study identifies therapeutic target for diabetic retinopathy

Specific cells in the retina trigger inflammation and vision impairment associated with diabetes, according to new research out of Case Western Reserve University School of Medicine.

9 Mar 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Neurotrophic factor GDNF regulates dopamine neurons in the brain, research shows

New research results are expanding our understanding of the physiological role of the glial cell line-derived neurotrophic factor GDNF in the function of the brain's dopamine systems.

15 Feb 2017

Study provides new insights into roles of different subareas in prefrontal cortex

Whether the brain responds to an external stimulus or not depends significantly on the balance between areas of excitation and inhibition in the prefrontal cortex (PFC).

10 Feb 2017

Non-invasive technique for examining fatty tissues could revolutionize medicinal drug testing

That's the hope of Associate Professor Noriyuki Yanaka and researchers at Hiroshima University who have developed a non-invasive way to assess the anti-inflammatory properties of fortified health foods and medications.

31 Jan 2017

Scientists decipher emergence of neuronal diversity in the cerebral cortex

The development of cerebral cortex plays a major role in the evolution of species and in particular for mankind.

30 Jan 2017

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

A bacterial by-product known to be important in maintaining gut health may slow the progression of amyotrophic lateral sclerosis, or ALS - a progressive, neurodegenerative disease.

27 Jan 2017

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body.

17 Jan 2017

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Tokyo Institute of Technology research: Gravitational biology: Real time imaging and transcriptome analysis of medaka aboard space station

11 Jan 2017

Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain.

10 Jan 2017

Experimental treatment approach reverses cognitive decline and neuropathology in AD mouse model

Treatment with an inhibitor of 12/15-lipoxygenase, an enzyme elevated in patients with Alzheimer's disease (AD), reverses cognitive decline and neuropathology in an AD mouse model, reports a new study in Biological Psychiatry.

5 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

C elegans could be powerful model for understanding how nervous systems produce behaviors

The human brain, the most complex object in the universe, has 86 billion neurons with trillions of yet-unmapped connections.

27 Dec 2016