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Nonmedical use of prescription opioids drops but overdose death rates rise in U.S.

From 2003 to 2013, the percentage of nonmedical use of prescription opioids decreased among adults in the U.S., while the prevalence of prescription opioid use disorders, frequency of use, and related deaths increased, according to a study in the October 13 issue of JAMA.

15 Oct 2015

Hands-free smartphones can simplify intravenous injection procedures

Failed injections could be reduced after researchers developed a way for smartphones to be used hands-free to locate veins in people’s arms.

13 Oct 2015

NC State scientists take a giant leap closer to understanding locomotion from the leg up

Using an "Avatar"-like bio-robotic motor system that integrates a real muscle and tendon along with a computer controlled nerve stimulator acting as the avatar's spinal cord, North Carolina State University researchers have taken a giant leap closer to understanding locomotion from the leg up.

13 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

FDA allows marketing of new EarLens Contact Hearing Device

The U.S. Food and Drug Administration today allowed marketing of a new hearing aid that uses a laser diode and direct vibration of the eardrum to amplify sound. The combination of laser light pulses and a custom-fit device component that comes in direct contact with the eardrum is designed to use the patient's own eardrum as a speaker and enables amplification over a wider range of frequencies for some hearing impaired persons.

9 Oct 2015

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Despite decades of study, schizophrenia has remained stubbornly difficult to diagnose in its earliest stage - between the appearance of symptoms and the development of the disorder. Now, a new analysis led by researchers at the UNC School of Medicine and the Renaissance Computing Institute identified illogical thoughts as most predictive of schizophrenia risk.

9 Oct 2015

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

The Brain & Behavior Research Foundation will honor nine scientists with its 2015 Outstanding Achievement Prizes for their work in schizophrenia, mood disorders, child and adolescent psychiatry, and cognitive neuroscience.

9 Oct 2015

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

Neurocrine Biosciences, Inc. announced today that NBI-98854, a highly selective small molecule VMAT2 inhibitor, showed a statistically significant reduction in tardive dyskinesia during the six weeks of placebo-controlled treatment in the Kinect 3 clinical trial. This Phase III trial included moderate to severe tardive dyskinesia patients with underlying schizophrenia, schizoaffective disorder, bipolar or major depressive disorder.

8 Oct 2015

New book suggests ways to reduce medical reversals

Medical reversal—when accepted medical interventions are abandoned because they are found to be ineffective—is the "most important problem in medicine today," according to the authors of a new book: Ending Medical Reversal.

8 Oct 2015

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Genocea Biosciences, Inc. (NASDAQ:GNCA), a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, has announced positive results from a planned interim analysis of data collected six months after dosing from its ongoing Phase 2 dose optimization trial evaluating GEN-003 for the treatment of genital herpes. At its best performing dose of 60 µg per protein / 75 µg of Matrix-M2TM adjuvant, GEN-003 demonstrated a statistically significant 58 percent reduction from baseline in the viral shedding rate (p < 0.0001), the primary endpoint of the study.

7 Oct 2015

Innovative one-year project aims to bridge gap between healthcare education and clinical practice

Caring for patients in an acute care setting in a hospital requires a team approach and involves a multitude of healthcare professionals including nurses, attending physicians, residents, case managers, pharmacists, and clinical psychologists to name a few. Each of these professions enters into practice with different skills sets, knowledge and professional identities that contribute to patient care. Yet, in many circumstances, barriers exist between disciplines that can obstruct a team-based system.

7 Oct 2015

Overall incidence of serious, highly drug-resistant group of bacteria relatively low in 2012-2013

The overall incidence in 2012-2013 was relatively low of a serious, highly drug-resistant group of bacteria (Carbapenem-resistant Enterobacteriaceae [CRE]) that are an important cause for health-care associated infections, according to a study published online by JAMA. Most CRE cases were associated with prior hospitalizations and discharge to long-term care settings.

6 Oct 2015

GE unveils different breast cancer tests for different breasts

With an estimated 494,000 new cases per year, breast cancer is by far the most common cancer amongst women across Europe. Particularly affected are women with dense breast tissue because of the difficultly it can cause when trying to detect cancer early using mammography.

5 Oct 2015

Calcitonin-gene related peptide antibody inhibition shows migraine prevention promise

TEV-48125, a monoclonal anti-calcitonin-gene related peptide antibody, is well tolerated and effective in the prevention of high-frequency episodic migraine and chronic migraine, findings from two phase IIb studies show.

2 Oct 2015

International team of scientists create world's largest catalog of genomic variations among humans

An international team of scientists from the 1000 Genomes Project Consortium has created the world's largest catalog of genomic differences among humans, providing researchers with powerful clues to help them establish why some people are susceptible to various diseases. While most differences in peoples' genomes - called variants - are harmless, some are beneficial, while others contribute to diseases and conditions, ranging from cognitive disabilities to susceptibilities to cancer, obesity, diabetes, heart disease and other disorders.

1 Oct 2015

Researchers develop strategies to prevent pediatric head injuries from toppled TV sets

Researchers from the University of Toronto and St. Michael's Hospital (Toronto, Ontario, Canada) reviewed medical articles describing head injuries caused by toppled television sets in children 0 to 18 years of age. These injuries, which can be severe and sometimes fatal in small children, are often unwitnessed by adult caregivers, indicating a lack of awareness of the dangers posed to toddlers by TV sets that are not securely mounted.

29 Sep 2015

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Pregnant women with systemic lupus erythematosus (SLE), are at higher risk for adverse pregnancy outcomes, including preeclampsia, placental insufficiency, fetal death, miscarriages, and other complications.

29 Sep 2015

Frequent infections in early life may increase risk factor for coeliac disease development in later life

Children with frequent infections in the first 18 months of life have a slightly increased risk of later developing coeliac disease compared with children who have few infections. This is the conclusion from a study by the Norwegian Institute of Public Health.

28 Sep 2015

Two-drug combination improves progression-free survival in patients with advanced melanoma

Patients with advanced melanoma skin cancer survive for longer without their disease progressing if they have been treated with a combination of two drugs, nivolumab and ipilimumab, than with either of these drugs alone. New results show that these patients also do better regardless of their age, stage of disease and whether or not they have a cancer-driving mutation in the BRAF gene.

28 Sep 2015

Research into 2-million-year-old human fossils reveals how hearing pattern resembles chimpanzees

Research into human fossils dating back to approximately two million years ago reveals that the hearing pattern resembles chimpanzees, but with some slight differences in the direction of humans.

26 Sep 2015

Frequency News and Research

Nonmedical use of prescription opioids drops but overdose death rates rise in U.S.

Hands-free smartphones can simplify intravenous injection procedures

NC State scientists take a giant leap closer to understanding locomotion from the leg up

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

FDA allows marketing of new EarLens Contact Hearing Device

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

New book suggests ways to reduce medical reversals

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Innovative one-year project aims to bridge gap between healthcare education and clinical practice

Overall incidence of serious, highly drug-resistant group of bacteria relatively low in 2012-2013

GE unveils different breast cancer tests for different breasts

Calcitonin-gene related peptide antibody inhibition shows migraine prevention promise

International team of scientists create world's largest catalog of genomic variations among humans

Researchers develop strategies to prevent pediatric head injuries from toppled TV sets

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Frequent infections in early life may increase risk factor for coeliac disease development in later life

Two-drug combination improves progression-free survival in patients with advanced melanoma

Research into 2-million-year-old human fossils reveals how hearing pattern resembles chimpanzees

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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