Genetic News and Research

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Loss of brain interneurons linked to cognitive deficits in aging

Normal aging is usually associated with a decline in memory, although it is unclear what factors play a role.

28 Sep 2023

Plastic waste in the oceans may spread antibiotic resistance

Bacteria discharged to the oceans in sewage and wastewater thrive on the biofilms that form on plastic waste. This may be leading to the somewhat unanticipated problem of antimicrobial resistance.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

Mothers' psychosocial stress during pregnancy has negative associations with children's sleep

Study shows that mothers' psychosocial stress during pregnancy has negative associations with their children's sleep that persist across childhood.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

New multi-polygenic scores boost coronary heart disease prediction accuracy

Two multi-polygenic scores (muti-PGs) to predict coronary heart disease (CHD).

28 Sep 2023

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Recent study in Scientific Reports finds a link between nonalcoholic fatty liver disease (NAFLD) and a higher risk of venous thromboembolism (VTE) among healthy Korean adults. The research suggests that NAFLD may contribute to a hypercoagulable state, increasing the risk of VTE.

27 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old - ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

New study reveals genetic overlap between schizophrenia and cardiovascular disease risk factors

New research finds that people with schizophrenia have a genetic propensity to smoking and a reduced genetic risk of obesity.

27 Sep 2023

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

Mutations on a key SARS-CoV-2 viral protein are linked to extreme immune responses and could offer a novel vaccine target.

27 Sep 2023

UKHSA donates advanced genomic surveillance equipment to CARPHA

This is a significant stride towards strengthening global genomic surveillance to track new variants and pathogens of pandemic and epidemic potential.

27 Sep 2023

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Rice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique in rodents, and their findings suggest that the efficiency of gene delivery improves within each targeted site when more sites are opened.

27 Sep 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

Genetic News and Research

Loss of brain interneurons linked to cognitive deficits in aging

Plastic waste in the oceans may spread antibiotic resistance

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Study uncovers previously unknown compensatory mechanism in liver disease

Mothers' psychosocial stress during pregnancy has negative associations with children's sleep

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

New multi-polygenic scores boost coronary heart disease prediction accuracy

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Researchers develop new way to boost immune cells' ability to fight TB

New study reveals genetic overlap between schizophrenia and cardiovascular disease risk factors

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Blocking Notch signaling pathway could reverse age-related bone loss

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Mutations on a key SARS-CoV-2 viral protein linked to extreme immune responses

UKHSA donates advanced genomic surveillance equipment to CARPHA

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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