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Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

University of Arizona Health Sciences researchers are taking the foot off the brake in their quest to improve opioid therapy while decreasing its side effects.

15 May 2023

Integrated proteomics approach identifies the contents of p62 bodies in detail

Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition progressing, a study says.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

Language exposure can shape the brains of young children

Talking to toddlers helps shape their developing brain, according to new research from the University of East Anglia.

15 May 2023

Experts provide a new clinical picture of sarcopenic obesity

Proteins and weight training could help if obese patients are suffering from muscle atrophy. However, the problem is usually not recognized, according to Prof. Dr. Bischoff from the University of Hohenheim.

15 May 2023

Carotenoids' potential in reducing chronic disease risk

Researchers explore the association between the gastrointestinal delivery system and carotenoids.

15 May 2023

SARS-CoV-2 variants show altered glycan processing

Researchers examine spike-protein trimers from SARS-CoV-2 variants to compare the N (asparagine)-glycan landscape.

15 May 2023

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Scientists explore the use of deep generative models in producing complete instances of as-yet undiscovered SARS-CoV2 Spike protein sequences. The resulting models substantially outperform a state-of-the-art generative model for protein sequences finetuned on SARS-CoV2 data.

14 May 2023

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Finding, cultivating, and bioengineering organisms that can digest plastic not only aids in the removal of pollution, but is now also big business.

13 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

AI used to build a 3D model of the Commander complex

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

11 May 2023

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

11 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

AI algorithm could soon be used to rapidly diagnose heart attacks with better accuracy

An algorithm developed using artificial intelligence could soon be used by doctors to diagnose heart attacks with better speed and accuracy than ever before, according to new research from the University of Edinburgh, funded by the British Heart Foundation and the National Institute for Health and Care Research, and published today in Nature Medicine.

11 May 2023

Protein C News and Research

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

Integrated proteomics approach identifies the contents of p62 bodies in detail

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Newly identified genetic variant provides protection from Alzheimer's disease

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Study sheds light on the importance of a subset of microglial cells in cognition and memory

Language exposure can shape the brains of young children

Experts provide a new clinical picture of sarcopenic obesity

Carotenoids' potential in reducing chronic disease risk

SARS-CoV-2 variants show altered glycan processing

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Using an intracellular toolkit to map organelle bio-geography in stem cells

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

AI used to build a 3D model of the Commander complex

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Targeting the hemoglobin problem in sickle cell disease using a new drug

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

AI algorithm could soon be used to rapidly diagnose heart attacks with better accuracy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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