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Essen Instruments, Origene Technologies partner to co-develop ion channel cell lines

Essen Instruments Inc. and OriGene Technologies, Inc. today announced a strategic alliance to co-develop ion channel cell lines. Essen, based in Ann Arbor Michigan, is a leading provider of life science products and services, including ion channel discovery and safety assays. OriGene, headquartered in Rockville, Maryland, specializes in the creation and supply of gene-centric products, and has a collection of over 30,000 human full length cDNA clones.

17 Mar 2010

CPCS announces new programs that focus on accidental poisoning prevention

As National Poison Prevention Week begins, the California Poison Control System announces ground-breaking new programs, including a free text messaging service, Facebook quizzes and e-cards to provide essential tips, news and information on poisoning, the second leading cause of childhood injury in the U.S. With more than two million poisonings reported each year to poison control centers across the country, this information is potentially life-saving.

17 Mar 2010

Study provides new perspective on cell movements

When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found.

17 Mar 2010

Genentech submits ACTEMRA sBLA to FDA

Genentech, Inc., a wholly-owned member of the Roche Group, today announced that the company submitted a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for ACTEMRA® (tocilizumab) for the prevention of structural joint damage (as assessed by radiograph) and improvement in physical function in adults with moderately to severely active rheumatoid arthritis (RA).

17 Mar 2010

Key cellular defect in protein synthesis can lead to cancer susceptibility

UCSF researchers have discovered that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility. The scientists also found that a new generation of inhibitory drugs offers promise in correcting this defect.

17 Mar 2010

Human amniotic fluid skin cells "reprogrammed" to pluripotency

In a breakthrough that may help fill a critical need in stem cell research and patient care, researchers at Mount Sinai School of Medicine have demonstrated that skin cells found in human amniotic fluid can be efficiently "reprogrammed" to pluripotency, where they have characteristics similar to human embryonic stem cells that can develop into almost any type of cell in the human body. The study is online now and will appear in print in the next issue of the journal Cellular Reprogramming, to be published next month.

16 Mar 2010

PCI Biotech completes treatment of third dose group in phase I/II study of Amphinex in cancer patients

PCI Biotech reported today that it has completed the treatment of the third dose group in the phase I/II study of its proprietary photosensitiser Amphinex® used in combination with the cytotoxic agent bleomycin in cancer patients.

16 Mar 2010

Sigma-Aldrich signs agreement to acquire Ace Animals

Sigma-Aldrich® today announced it has signed an agreement to acquire Ace Animals, Inc., a Berks County, PA.-based provider of high quality research rodents to the biomedical industry.

16 Mar 2010

Tolerx publishes follow-up data from study of otelixizumab therapy for new onset T1DM patients

Tolerx, Inc., today announced the publication in Diabetologia, the journal of the European Association for the Study of Diabetes, of the four-year follow-up clinical data from new onset type 1 diabetes (T1DM) patients (age 12-39) who received a single short course of therapy with otelixizumab (ChAglyCD3).

16 Mar 2010

Blocking RhoA enzyme increases survival in SMA mouse model

Scientists from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have identified a promising new approach for developing drugs to treat Spinal muscular atrophy (SMA), the leading inherited cause of death in infants and toddlers. Dr. Rashmi Kothary and his doctoral student Melissa Bowerman have found that an enzyme called RhoA is overly active in a mouse model of the disease and blocking this enzyme can greatly increase survival. The study is published in Human Molecular Genetics.

16 Mar 2010

AssistMed, Definitive Homecare Solutions enter into strategic alliance

AssistMed, Inc. today announced it has signed a strategic partnership agreement with Definitive Homecare Solutions, Ltd. to develop and offer an interface between AssistMed's Patient Adherence Solutions and Definitive Homecare Solutions' CPR+ patient and business management software designed for specialty pharmacy customer applications.

16 Mar 2010

Cytheris study: rhIL-7 treatment restores T cell trafficking and improves survival in animal model of sepsis

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced publication of data from a preclinical study in a clinically relevant animal model of sepsis showing that recombinant human Interleukin-7 (rhIL-7) treatment not only restores T cell trafficking and function, but also translates into improved survival.

16 Mar 2010

Kinexus Bioinformatics launches new peptide synthesis facility

Kinexus Bioinformatics Corporation, a world leader in functional proteomics research, announced the launch of a new peptide synthesis facility to provide researchers with the latest in peptide array technologies. These new services will facilitate and expedite access to peptide platforms for innovative approaches to proteomic research and discovery.

16 Mar 2010

Promedior raises $12M in Series C financing

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat inflammatory and fibrotic diseases, today announced that it has raised $12 million in a Series C financing round. Forbion Capital Partners led the round, with participation from existing investors Morgenthaler Ventures, HealthCare Ventures, Polaris Venture Partners, and Easton Capital. The Series C financing brings the total capital raised by Promedior over the past year to $27 million.

16 Mar 2010

Aging and Alzheimer's disease: Novel brain imaging technologies help create new insights

The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain. These plaques can be measured in humans with PET scans that use a chemical marker or radiotracer called 11C-PIB.

16 Mar 2010

BeaconEquity.com: STEM losses $5.2M in fourth-quarter of 2009

BeaconEquity.com announces an investment report featuring biotech company StemCells Inc. The report includes financial, comparative and investment analyses, and pertinent industry information you need to know to make an educated investment decision.

16 Mar 2010

Workings of IGFs on muscle cells

The muscle-building abilities of hormones known as insulin-like growth factors (IGFs) are legendary. Just do an online search and you'll find not only scientific papers discussing the effects of IGFs on the cells that give rise to muscle tissue, but also scores of ads touting the purported benefits of IGF supplements for bodybuilding.

16 Mar 2010

Mathematical model may promote medical research on how to grow new organs

Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms.

16 Mar 2010

New method may shed light on the mechanism behind folding and misfolding of proteins

Researchers at the Department of Chemistry at the Technische Universit-t M-nchen (TUM) have developed a method that allows the observation of local movements in proteins on a time scale of nanoseconds to microseconds.

16 Mar 2010

Dual role of Notch signalling pathway

Scientists headed by ICREA researcher Marco Mil-n, at the Institute for Research in Biomedicine (IRB Barcelona), reveal a surprising new function of Notch protein that contrasts with the one known to date. Found in the cell membrane, this protein activates a signalling pathway that regulates the expression of genes that make the cell divide, grow, migrate, specialise or die.

16 Mar 2010