B Cell News and Research

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Researchers discover mechanism that protects tissue after faulty gene expression

The genetic material, in the form of DNA, contains the information that is crucial for the correct functioning of every human and animal cell.

2 Feb 2024

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

2 Feb 2024

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

2 Feb 2024

Unveiling HIV's "latch": New study reveals key to blocking infection

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.

2 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

New study identifies key role of microRNA-29 in scar-free wound healing

New findings in The American Journal of Pathology, published by Elsevier, report that a class of small RNAs (microRNAs), microRNA-29, can restore normal skin structure rather than producing a wound closure by a connective tissue (scar).

2 Feb 2024

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

A study published in Science on Feb. 1 reported a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level.

2 Feb 2024

Scientists discover orderly structure hidden within bacterial biofilms

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

2 Feb 2024

Viscoelasticity emerges as key marker for liver cancer in diabetes

For centuries, doctors have used their hands as essential diagnostic tools - exploring joints and palpating abdomens to assess a patient's health.

2 Feb 2024

Researchers find new clue to treating aggressive Wilms tumor subtype

An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy.

2 Feb 2024

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

2 Feb 2024

Yokogawa introduces CellVoyager High-Content Analysis System CQ3000

The CQ3000 will be showcased at SLAS2024 Boston, MA, February 3-7 with live on-booth demonstrations (booth #485)

From Yokogawa Life Science 2 Feb 2024

A promising approach for aging research

In mid-January 2024, the Friedrich Schiller University Jena made an important discovery public: A team of researchers from the universities of Jena and Shenzhen (China), as well as the Jena University Hospital, decoded a molecular mechanism that plays a crucial role in the development of breast cancer.

1 Feb 2024

New insights on how diet regulates allergic responses

The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life.

1 Feb 2024

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset.

1 Feb 2024

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

1 Feb 2024

Researchers develop new method to study liver function and disease

Researchers at Karolinska Institutet in Sweden have developed a method to study liver function and disease without requiring invasive procedures.

1 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

B Cell News and Research

Researchers discover mechanism that protects tissue after faulty gene expression

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Unveiling HIV's "latch": New study reveals key to blocking infection

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

New study identifies key role of microRNA-29 in scar-free wound healing

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

Scientists discover orderly structure hidden within bacterial biofilms

Viscoelasticity emerges as key marker for liver cancer in diabetes

Researchers find new clue to treating aggressive Wilms tumor subtype

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

Yokogawa introduces CellVoyager High-Content Analysis System CQ3000

A promising approach for aging research

New insights on how diet regulates allergic responses

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

Researchers develop new method to study liver function and disease

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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