Antibodies News and Research

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New article explores the endemic potential of COVID-19 virus

A new article by Columbia Mailman School researchers Jeffrey Shaman and Marta Galanti explores the potential for the COVID-19 virus to become endemic, a regular feature producing recurring outbreaks in humans.

16 Oct 2020

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Now, a recent study published on the preprint server bioRxiv in October 2020 reports the development of a rapid process for generating high-affinity mouse mAbs, and their functional attributes.

16 Oct 2020

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

As scientists scramble to find effective vaccines and antivirals for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a recent study published on the preprint server bioRxiv in October 2020 reports that the use of convalescent plasma to treat COVID-19 disease early in the course of the illness may be among the best available strategies at present.

16 Oct 2020

Synthetic signals could help control tissue regeneration, guide cellular therapies

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Now, a team of scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered potent novel anti-microbial molecules from toxic proteins found in wasp venom. The researchers believe that the discovery holds promise in fighting the increasing number of antibiotic-resistant bacteria, that cause serious illness.

15 Oct 2020

Previous infections with seasonal coronaviruses might protect against SARS-CoV-2

Seasonal coronaviruses, which generally cause mild respiratory illness and symptoms of the common cold, belong to the same viral family as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes COVID-19.

15 Oct 2020

Obese persons have greater risk of developing severe COVID-19

The probability that an obese person will develop severe COVID-19 is high regardless of age, sex, ethnicity, and the presence of co-morbidities such as diabetes, high blood pressure, and heart or lung disease, according to a study by Brazilian researchers published in Obesity Research & Clinical Practice.

15 Oct 2020

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

As COVID-19 seems to be making a comeback in many areas of the world, including Japan, a new study published on the preprint server medRxiv in October 2020 shows the relevance of microsamples of blood in serosurveillance of this disease.

15 Oct 2020

Rapid SARS‐CoV‐2 IgM‐IgG combined antibody test

A recent study published on the preprint server medRxiv in October 2020 reports a new diagnostic test for SARS-CoV-2 based on the detection of antibodies.

15 Oct 2020

Human bivalent SARS-CoV-2 neutralizing antibodies more potent

A recent study published on the preprint server bioRxiv in October 2020 reports more effective viral neutralization by bivalent anti-spike antibodies. This could promote the development of better therapeutics and vaccines.

15 Oct 2020

Certain live-attenuated vaccines can prevent severe complications of COVID-19

COVID-19 continues to wreak havoc globally, with over one million deaths to date. Yet what if an existing vaccine could make COVID-19 less deadly? A study just published put the theory to test, with promising results.

15 Oct 2020

The COVID-19 vaccine pipeline

Researchers from Mayo Clinic, United States of America, have reviewed the immunity developed against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

14 Oct 2020

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Today, the U.S. Food and Drug Administration approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients.

14 Oct 2020

Army researchers team up to test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale.

14 Oct 2020

Research identifies antigen-specific peripheral T follicular helper cells in COVID-19 infected patients

Researchers have found peripheral T follicular helper cell responses to different structural proteins of SARS-CoV-2 and have studied how the response occurs over time.

14 Oct 2020

Researchers use single cell sequencing technology to characterize immune system of COVID-19 patients

In this study, which was published in the journal Frontiers in Immunology on September 30th, researchers used sequencing to characterize the immune system of patients who survive from COVID-19 infection from symptom onset through recovery.

14 Oct 2020

Study shows SARS-CoV-2 antibodies offer lasting immunity

One of the most significant questions about the novel coronavirus is whether people who are infected are immune from reinfection and, if so, for how long.

14 Oct 2020

NIH launches new study to streamline COVID-19 treatments for larger clinical studies

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today launched a study designed to determine whether certain approved therapies or investigational drugs in late-stage clinical development show promise against COVID-19 and merit advancement into larger clinical trials.

14 Oct 2020

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

In a new clinical trial, UC Davis Health will test the effectiveness and safety of REGN-COV2, the monoclonal antibody cocktail, in preventing COVID-19 in adults living with infected patients.

14 Oct 2020

Antibodies News and Research

New article explores the endemic potential of COVID-19 virus

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

Synthetic signals could help control tissue regeneration, guide cellular therapies

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Previous infections with seasonal coronaviruses might protect against SARS-CoV-2

Obese persons have greater risk of developing severe COVID-19

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

Rapid SARS‐CoV‐2 IgM‐IgG combined antibody test

Human bivalent SARS-CoV-2 neutralizing antibodies more potent

Certain live-attenuated vaccines can prevent severe complications of COVID-19

The COVID-19 vaccine pipeline

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Army researchers team up to test alternative ways to measure COVID-19 antibody levels

Research identifies antigen-specific peripheral T follicular helper cells in COVID-19 infected patients

Researchers use single cell sequencing technology to characterize immune system of COVID-19 patients

Study shows SARS-CoV-2 antibodies offer lasting immunity

NIH launches new study to streamline COVID-19 treatments for larger clinical studies

New clinical trial to test safety and efficacy of antibody cocktail against COVID-19

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