Fatigue News and Research

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Folotyn approved for the treatment of Peripheral T-Cell Lymphoma

The U.S. Food and Drug Administration has approved Folotyn (pralatrexate), the first treatment for a form of cancer known as Peripheral T-cell Lymphoma (PTCL), an often aggressive type of non-Hodgkins lymphoma.

25 Sep 2009

Research to develop small-molecule drug that blocks excess iron absorption

Excess iron in the body, if left unchecked, can form toxic deposits in major organs leading to serious conditions including heart failure, diabetes, liver cirrhosis, arthritis, and even infertility. Iron overload can be a consequence of a genetically mutated gene known as hereditary hemochromatosis, or a consequence of red blood cell transfusions, required as life saving treatments, for patients with diseases such as thalassemia.

25 Sep 2009

Two new studies test conventional wisdom about physician behavior

Two new studies test classic assumptions about doctor behavior, including whether fatigue, stress and even full moons impede their work. Meanwhile, separate reports investigate would-be physicians' behavior far from the exam room or operating table -- on Facebook, YouTube, and private blogs.

24 Sep 2009

Phase 1b interim clinical trial results of IMO-2055, Tarceva and Avast combination announced

Idera Pharmaceuticals (Nasdaq: IDRA) today presented interim data from a phase 1b, single arm clinical trial evaluating IMO-2055, an agonist of Toll-like Receptor (TLR) 9, in combination with Tarceva® and Avastin® in patients with non-small cell lung cancer (NSCLC).

23 Sep 2009

Phase 1 extension study results of Plexxikon's PLX4032 in metastatic melanoma patients encouraging

Plexxikon Inc. today announced encouraging clinical data from a Phase 1 extension study of PLX4032 (RG7204) in metastatic melanoma patients, which expand the results announced from the initial phase of the study. PLX4032 is a novel, oral and highly selective drug that targets the BRAFV600E cancer-causing mutation that occurs in about 50 percent of melanomas and about eight percent of all solid tumors.

23 Sep 2009

NIST collaborates with private industry to release a new reference material for beryllium

Researchers at the National Institute of Standards and Technology (NIST), in collaboration with private industry and other government agencies, have produced a new reference material for beryllium. Beryllium, an exotic rare-earth metal used as a hardener in high-performance alloys and ceramics, can cause berylliosis-a chronic, incurable and sometimes fatal illness.

23 Sep 2009

Professional and personal distress levels high in primary care physicians

Primary care physicians who participated in an educational program that included an emphasis on mindful communication reported improvement in personal well-being, emotional exhaustion, empathy and attitudes associated with patient-centered care, according to a study in the September 23/30 issue of JAMA, a theme issue on medical education.

23 Sep 2009

Medical errors: Cause for stress in resident physicians

Internal medicine residents who reported higher levels of fatigue and distress were more likely to report a medical error, according to a study in the September 23/30 issue of JAMA, a theme issue on medical education.

23 Sep 2009

Distress and fatigue among medical residents can lead to significant risk of medical error: Study

Mayo Clinic researchers report that distress and fatigue among medical residents are independent contributors to self-perceived medical errors. The findings appear today in the Journal of the American Medical Association (JAMA).

23 Sep 2009

Event to address rheumatoid arthritis

26 men and women with RA from across europe honoured as they share their inspirational stories. Actress, artist and activist Jane Seymour will host the first My Day for RA European event in Barcelona, Spain this evening to recognise the daily challenges, hopes and achievements of people living with rheumatoid arthritis (RA).

22 Sep 2009

Bioscience Research offers mental health care at no cost

Psychiatrists at Bioscience Research, LLC, understand the mental health burden that can accompany unemployment and the day-to-day stress of looking for a new job or worrying about losing an existing job.

22 Sep 2009

Bayer's regorafenib showed 50% stabilization rate in RCC patients

Bayer today announced results from a Phase II trial of regorafenib (BAY 73-4506), a potent oral multi-kinase inhibitor, which demonstrated that treatment with regorafenib resulted in a 31 percent partial response rate and 50 percent stabilization rate in patients with metastatic renal cell carcinoma (RCC).

22 Sep 2009

Mild exercises for the bed-bound patients helps to combat muscle wasting

Critical care experts at Johns Hopkins are reporting initial success in boosting recovery and combating muscle wasting among critically ill, mostly bed-bound patients using any one of a trio of mild physical therapy exercises during their stays in the intensive care unit (ICU).

22 Sep 2009

Interim data from Micromet's T-cell engaging BiTE antibody study for treating solid tumors

Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, today presented first interim data from a phase 1 dose-escalation clinical study for BiTE antibody MT110, the first T-cell engaging antibody for the treatment of solid tumors.

22 Sep 2009

Study reveals that patients with NSCLC who received maintenance therapy with ALIMTA showed survival benefit

Data published today in The Lancet showed a survival benefit in nonsquamous patients with advanced non-small cell lung cancer (NSCLC) who received maintenance therapy with ALIMTA(R) (pemetrexed for injection) plus best supportive care as compared to placebo plus best supportive care.

21 Sep 2009

Study reveals that KCNE2 and KCNQ1 mutations can results in thyroid dysfunction

Genes previously known to be essential to the coordinated, rhythmic electrical activity of cardiac muscle -- a healthy heartbeat -- have now also been found to play a key role in thyroid hormone (TH) biosynthesis, according to Weill Cornell Medical College researchers.

21 Sep 2009

EPO and growth factor therapy safe for anemic MDS patients

Myelodysplastic syndromes (MDS), a group of blood disorders that can lead to acute myeloid leukemia (AML) in some patients, often cause severe anemia (when the body lacks a sufficient number of functional red blood cells).

18 Sep 2009

Educational initiative proves successful in identifying and diagnosing fibromyalgia

According to The Johns Hopkins University School of Medicine, the Fibromyalgia Circle of Care Initiative has achieved dramatic success in heightening awareness, diagnosis and best practice treatment of fibromyalgia – a complex and chronic pain disorder that plagues an estimated 10 million Americans.

17 Sep 2009

Research study on Lyme disease

Potentially debilitating Lyme disease doesn't afflict people everywhere that the ticks harboring it are found. At least not yet. A five-university consortium led by a Michigan State University researcher wants to find out why.

17 Sep 2009

Four H1N1 vaccines approved by FDA

The U.S. Food and Drug Administration announced today that it has approved four vaccines against the 2009 H1N1 influenza virus. The vaccines will be distributed nationally after the initial lots become available, which is expected within the next four weeks.

16 Sep 2009

Fatigue News and Research

Folotyn approved for the treatment of Peripheral T-Cell Lymphoma

Research to develop small-molecule drug that blocks excess iron absorption

Two new studies test conventional wisdom about physician behavior

Phase 1b interim clinical trial results of IMO-2055, Tarceva and Avast combination announced

Phase 1 extension study results of Plexxikon's PLX4032 in metastatic melanoma patients encouraging

NIST collaborates with private industry to release a new reference material for beryllium

Professional and personal distress levels high in primary care physicians

Medical errors: Cause for stress in resident physicians

Distress and fatigue among medical residents can lead to significant risk of medical error: Study

Event to address rheumatoid arthritis

Bioscience Research offers mental health care at no cost

Bayer's regorafenib showed 50% stabilization rate in RCC patients

Mild exercises for the bed-bound patients helps to combat muscle wasting

Interim data from Micromet's T-cell engaging BiTE antibody study for treating solid tumors

Study reveals that patients with NSCLC who received maintenance therapy with ALIMTA showed survival benefit

Study reveals that KCNE2 and KCNQ1 mutations can results in thyroid dysfunction

EPO and growth factor therapy safe for anemic MDS patients

Educational initiative proves successful in identifying and diagnosing fibromyalgia

Research study on Lyme disease

Four H1N1 vaccines approved by FDA

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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