Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Study reveals novel mechanism driving hypertension-induced arterial disease

A new study in Advanced Science unlocks the secrets of how high blood pressure (hypertension) fuels the progression of arterial disease.

5 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

New study shows intermittent fasting reduces obesity-related brain inflammation and cognitive decline

The long-term beneficial effects of intermittent fasting (IF).

5 Jan 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.

4 Jan 2024

Researchers discover PPFIA3 gene as a cause of previously unknown syndromic neurodevelopmental disorder

An international collaborative study led by postdoctoral scientist, Dr. Maimuna Paul, and child neurologist, Dr. Hsiao-Tuan Chao, an assistant professor at Baylor College, a faculty member with the Cain Pediatric Neurology Research Foundation Laboratories at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, and an investigator at the McNair Medical Institute with The Robert and Janice McNair Foundation, recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic neurodevelopmental disorder.

4 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Novel approach to de novo protein design enables creation of diverse functional structures

A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin.

4 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

AI model predicts future spread of SARS-CoV-2 variants using genomic data

Researchers developed an AI-based model to predict the spread of new SARS-CoV-2 variants, analyzing nine million genomic sequences across 30 countries and incorporating factors like vaccination rates and non-pharmaceutical interventions.

4 Jan 2024

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins - and ultimately affect aging.

4 Jan 2024

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Researchers explored the effects of a small humanin-like peptide 2 (SHLP2) variant on mitochondrial function.

4 Jan 2024

Protein News and Research

Further Reading

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Study reveals novel mechanism driving hypertension-induced arterial disease

IKAROS: Unlocking the secrets of the immune system's key player

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

Unlocking the power of diet: How miRNAs influence health and disease

New study shows intermittent fasting reduces obesity-related brain inflammation and cognitive decline

YAP and TAZ proteins guide bone development in the womb

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy

Researchers discover PPFIA3 gene as a cause of previously unknown syndromic neurodevelopmental disorder

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Novel approach to de novo protein design enables creation of diverse functional structures

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

AI model predicts future spread of SARS-CoV-2 variants using genomic data

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Salk scientists map brain circuit triggering the crippling panic attacks

Gut microbiome plays a role in immune response to mRNA COVID vaccines

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Could your diet impact endometriosis? Research points to dietary insights for treatment

Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease

Ultimate guide to the essential tools for the characterization of proteins, polymers and nanoparticles eBook

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