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Researchers uncover genes that can suppress HCV infection within the liver

University of Adelaide researchers have uncovered the role played by a family of genes, which can suppress hepatitis C virus (HCV) infection within the liver.

28 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

Expectant mothers need to avoid certain cosmetics, cleaning agents and medicines during first trimester

Expectant mothers in their first trimester should avoid certain cosmetics, cleaning agents and medicines, to protect the developing fetal brain from chemicals that can trigger autism, York U health researchers have found.

27 Oct 2015

Culprit B cells identified for MS

Researchers have identified a subset of B cells that contribute to multiple sclerosis pathology independently of antibody production.

22 Oct 2015

American Cancer Society updates mammogram guidelines

The American Cancer Society has issued new recommendations on when women should get mammograms and how frequently they should get them. This is in contrast to the previous guidelines which stated that women should get them at age 40.

22 Oct 2015

NHS Trusts not compliant with safer sharps rules two years after regulation enacted, says new MindMetre reseach

New research from independent research organization MindMetre has revealed that many NHS Trusts are not complying with ‘safer sharps’ rules, putting NHS employees at unnecessary risk of ‘needlestick’ injuries and possible blood-borne infections such as hepatitis and HIV.

22 Oct 2015

Study reveals link between TV viewing and adolescents' beliefs about health risks of fast-food consumption

Television programs and commercials displaying fast food consumption that target young people are on the rise. While experts agree that television can entertain and inform, most TV programs and advertisements portray no negative consequences of fast food consumption. New research found that the rise of positive fast food imagery on TV strongly biases the views of children and can lead to negative influences on childhood behavior and values.

20 Oct 2015

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Lexicon Pharmaceuticals, Inc.'s telotristat etiprate, the first oral therapy in development for the treatment of carcinoid syndrome (CS), was associated with patient-reported improvements in social and physical function and emotional well-being according to new exit interview data from the Phase 3 TELESTAR study presented at the 2015 Neuroendocrine Tumor Society Annual Symposium in Austin, Texas.

19 Oct 2015

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

A research group at Tohoku Medical Megabank Organization (ToMMo) has successfully constructed a Japanese population reference panel (1KJPN), from the genome information of 1,070 individuals who had participated in the cohort studies of the Tohoku Medical Megabank Project.

19 Oct 2015

Study reveals high rates of preventable cancers in Indigenous peoples of high-income countries

Research published in The Lancet Oncology, led by the International Agency for Research on Cancer (IARC) on the scale and profile of cancer in indigenous peoples of the USA, Canada, Australia and New Zealand has revealed high rates of often preventable cancers including lung and cervical cancer, emphasising the need for targeted prevention strategies in these populations.

16 Oct 2015

Nonmedical use of prescription opioids drops but overdose death rates rise in U.S.

From 2003 to 2013, the percentage of nonmedical use of prescription opioids decreased among adults in the U.S., while the prevalence of prescription opioid use disorders, frequency of use, and related deaths increased, according to a study in the October 13 issue of JAMA.

15 Oct 2015

Hands-free smartphones can simplify intravenous injection procedures

Failed injections could be reduced after researchers developed a way for smartphones to be used hands-free to locate veins in people’s arms.

13 Oct 2015

NC State scientists take a giant leap closer to understanding locomotion from the leg up

Using an "Avatar"-like bio-robotic motor system that integrates a real muscle and tendon along with a computer controlled nerve stimulator acting as the avatar's spinal cord, North Carolina State University researchers have taken a giant leap closer to understanding locomotion from the leg up.

13 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

FDA allows marketing of new EarLens Contact Hearing Device

The U.S. Food and Drug Administration today allowed marketing of a new hearing aid that uses a laser diode and direct vibration of the eardrum to amplify sound. The combination of laser light pulses and a custom-fit device component that comes in direct contact with the eardrum is designed to use the patient's own eardrum as a speaker and enables amplification over a wider range of frequencies for some hearing impaired persons.

9 Oct 2015

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Despite decades of study, schizophrenia has remained stubbornly difficult to diagnose in its earliest stage - between the appearance of symptoms and the development of the disorder. Now, a new analysis led by researchers at the UNC School of Medicine and the Renaissance Computing Institute identified illogical thoughts as most predictive of schizophrenia risk.

9 Oct 2015

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

The Brain & Behavior Research Foundation will honor nine scientists with its 2015 Outstanding Achievement Prizes for their work in schizophrenia, mood disorders, child and adolescent psychiatry, and cognitive neuroscience.

9 Oct 2015

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

Neurocrine Biosciences, Inc. announced today that NBI-98854, a highly selective small molecule VMAT2 inhibitor, showed a statistically significant reduction in tardive dyskinesia during the six weeks of placebo-controlled treatment in the Kinect 3 clinical trial. This Phase III trial included moderate to severe tardive dyskinesia patients with underlying schizophrenia, schizoaffective disorder, bipolar or major depressive disorder.

8 Oct 2015

New book suggests ways to reduce medical reversals

Medical reversal—when accepted medical interventions are abandoned because they are found to be ineffective—is the "most important problem in medicine today," according to the authors of a new book: Ending Medical Reversal.

8 Oct 2015

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Genocea Biosciences, Inc. (NASDAQ:GNCA), a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, has announced positive results from a planned interim analysis of data collected six months after dosing from its ongoing Phase 2 dose optimization trial evaluating GEN-003 for the treatment of genital herpes. At its best performing dose of 60 µg per protein / 75 µg of Matrix-M2TM adjuvant, GEN-003 demonstrated a statistically significant 58 percent reduction from baseline in the viral shedding rate (p < 0.0001), the primary endpoint of the study.

7 Oct 2015

Frequency News and Research

Researchers uncover genes that can suppress HCV infection within the liver

Scientists decode central signal switch associated with epileptic seizures

Expectant mothers need to avoid certain cosmetics, cleaning agents and medicines during first trimester

Culprit B cells identified for MS

American Cancer Society updates mammogram guidelines

NHS Trusts not compliant with safer sharps rules two years after regulation enacted, says new MindMetre reseach

Study reveals link between TV viewing and adolescents' beliefs about health risks of fast-food consumption

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

Study reveals high rates of preventable cancers in Indigenous peoples of high-income countries

Nonmedical use of prescription opioids drops but overdose death rates rise in U.S.

Hands-free smartphones can simplify intravenous injection procedures

NC State scientists take a giant leap closer to understanding locomotion from the leg up

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

FDA allows marketing of new EarLens Contact Hearing Device

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

New book suggests ways to reduce medical reversals

Genocea announces positive data in Phase 2 trial evaluating GEN-003 for the treatment of genital herpes

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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