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New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

A new Practice Guideline and Practice Guidance in Hepatology will help improve the diagnosis and treatment of patients with liver cancer as well as patients with non-alcoholic fatty liver disease (NAFLD), which can lead to liver cancer and is characterized by the build-up of extra fat in liver cells often due to obesity and diabetes.

27 Jan 2018

Report highlights risk of severe injuries caused by swallowed button batteries from 'fidget spinners'

A report of two young children with burns of the esophagus caused by swallowed button batteries from "fidget spinners" highlights a risk of severe injuries involving these popular toys, according to a series of reports in the January/February Journal of Pediatric Gastroenterology and Nutrition.

27 Jan 2018

Researchers identify potential enzyme as therapeutic target for type 2 diabetes

Abnormalities in glucose uptake by the liver (or hepatic glucose uptake; HGU) cause elevations in blood glucose levels following meals, a state that is known as postprandial hyperglycemia.

27 Jan 2018

Phototherapeutic technology shows potential as anti-cancer weapon

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy - which is limited to the skin and areas accessible with an endoscope - this technique can target and attack cancer cells that have spread deep inside the body, according to researchers at Washington University School of Medicine in St. Louis.

25 Jan 2018

Computer modeling and simulation may help characterize injury from blasts on a battlefield

Sandia National Laboratories is developing specialized computer modeling and simulation methods to better understand how blasts on a battlefield could lead to traumatic brain injury and injuries to vital organs, like the heart and lungs.

24 Jan 2018

NIH launches large study to compare treatments for pregnant women with HIV

The National Institutes of Health has launched a large international study to compare the safety and efficacy of three antiretroviral treatment regimens for pregnant women living with HIV and the safety of these regimens for their infants.

24 Jan 2018

Scientists imitate the Human Blood-retinal barrier on a microfluidic chip

For years scientists have sought to minimise Animal testing and speed up clinical trials. One alternative is the use of in vitro assays using live cells, but its effectiveness is limited, since it is difficult to reproduce interaction and interconnection between cells.

24 Jan 2018

States face costly conundrum: How to treat inmates with hepatitis C

In a corner of Jymie Jimerson’s house in the town of Sparta, in southwestern Missouri, she has set up a kind of shrine. It has Native American art representing her Cherokee heritage alongside Willie Nelson albums, books and photos in remembrance of her late husband.

23 Jan 2018

Researchers block common siren call of glioblastoma and metastatic breast cancer

Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.

23 Jan 2018

Powerful anti-oxidant can stop progression of fatty liver disease in young mice

As obesity continues to rise in the U.S., non-alcoholic fatty liver disease (NAFLD) has become a major public health issue, increasingly leading to cancer and liver transplants.

22 Jan 2018

C-Path receives support from European Medicines Agency for liver injury biomarker

Critical Path Institute announced today that the European Medicines Agency has issued a Letter of Support for measurement of glutamate dehydrogenase (GLDH) as a biomarker of hepatocellular liver injury.

22 Jan 2018

Drinking during late adolescence could be first step to liver problems in adulthood

Alcohol is the leading cause of liver cirrhosis and liver-related deaths. Results of a large long-term study in Sweden have confirmed that drinking during late adolescence could be the first step towards liver problems in adulthood and that guidelines for safe alcohol intake in men might have to be revised downwards, reports the Journal of Hepatology.

22 Jan 2018

Researchers develop single blood test that screens for 8 cancer types

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

19 Jan 2018

Toothpaste ingredient could be employed as anti-malarial drug against drug-resistant parasites

An ingredient commonly found in toothpaste could be employed as an anti-malarial drug against strains of malaria parasite that have grown resistant to one of the currently-used drugs.

19 Jan 2018

$500 cancer detection blood tests may soon become reality

According to latest breakthrough in research, a blood test to detect eight common cancers, even before their symptoms begin to appear, may become a reality soon. The study report appears in the latest issue of the journal Science and gives hope for early detection of these deadly diseases when it could still be treated more effectively.

18 Jan 2018

Bile acids: A new therapy against obesity

Obesity arises from an imbalance between energy intake and energy expenditure. As a result, current treatments try to decrease calorie intake and/or increase energy expenditure.

17 Jan 2018

Bile acids could directly burn away lipids in the fat depots

The EPFL scientists discovered that bile acids can turn fat-storing cells into fat-burning ones. This process is called thermogenesis (literally, "heat production") and it helps maintain body temperature in cold environments.

16 Jan 2018

Johns Hopkins gets approval to perform HIV positive to HIV positive living donor kidney transplants

Johns Hopkins hopes to become the first hospital in the U.S. to perform HIV-positive to HIV-positive organ transplants from living donors.

16 Jan 2018

Scarring of fat tissue in obese people can make weight loss more difficult

The fat of obese people becomes distressed, scarred and inflamed, which can make weight loss more difficult, research at the University of Exeter has found.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

Liver News and Research

New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

Report highlights risk of severe injuries caused by swallowed button batteries from 'fidget spinners'

Researchers identify potential enzyme as therapeutic target for type 2 diabetes

Phototherapeutic technology shows potential as anti-cancer weapon

Computer modeling and simulation may help characterize injury from blasts on a battlefield

NIH launches large study to compare treatments for pregnant women with HIV

Scientists imitate the Human Blood-retinal barrier on a microfluidic chip

States face costly conundrum: How to treat inmates with hepatitis C

Researchers block common siren call of glioblastoma and metastatic breast cancer

Powerful anti-oxidant can stop progression of fatty liver disease in young mice

C-Path receives support from European Medicines Agency for liver injury biomarker

Drinking during late adolescence could be first step to liver problems in adulthood

Researchers develop single blood test that screens for 8 cancer types

Toothpaste ingredient could be employed as anti-malarial drug against drug-resistant parasites

$500 cancer detection blood tests may soon become reality

Bile acids: A new therapy against obesity

Bile acids could directly burn away lipids in the fat depots

Johns Hopkins gets approval to perform HIV positive to HIV positive living donor kidney transplants

Scarring of fat tissue in obese people can make weight loss more difficult

Research provides insights into mechanisms governing healthy longevity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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