Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Mologic launches new lab-based COVID-19 antibody tests

Mologic Ltd, a leading developer of rapid diagnostic technologies, announced that it will begin manufacturing its laboratory diagnostic test for COVID-19.

20 Apr 2020

New high-throughput approach yields libraries of probes for immunological assays

An immunological test known as a "tetramer assay" can detect T cells in a blood sample that recognize a specific antigen.

20 Apr 2020

Novel coronavirus mutation could spell trouble for vaccine development

New research shows that the novel coronavirus is undergoing mutations that could make it challenging to develop a vaccine against. There are a few vaccine candidates that are in the making to prevent COVID-19. With a potential for mutation, the vaccines that are being developed now may not work against the emergent mutated strains worry Taiwanese and Australian researchers. The study is titled, “Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of 2 RBD mutant with lower ACE2 binding affinity.”

19 Apr 2020

UC San Diego Health launches serological tests to detect past exposure to novel coronavirus

Clinical laboratory physicians and scientists at UC San Diego Health have launched a pair of serological tests that will look for novel coronavirus antibodies -- evidence in persons tested that they have previously been infected by SARS-CoV-2, the viral cause of COVID-19, even if they never experienced tell-tale symptoms.

18 Apr 2020

Nasal smear as screening test for allergic rhinitis

Stuffy noses, itching and fits of sneezing - 130 million people in Europe suffer from hay fever and other forms of allergic rhinitis. Until now, these conditions have typically been diagnosed using blood samples or skin prick tests.

17 Apr 2020

Researchers discover unique structure and function of rotavirus VP3 protein

After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine.

17 Apr 2020

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Are overactive immune cells causing COVID-19-related deaths?

While the COVID-19 pandemic is devastating many regions, the world over, a new paper published in the Journal of Experimental Medicine in April 2020 describes the possibility that the critical or very severe cases of COVID-19 are due to the production of neutrophil extracellular traps (NET) due to hyperactivated immune cells.

16 Apr 2020

Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

FDA grants Emergency Use Authorization to Ortho’s COVID-19 total antibody test

The U.S. Food and Drug Administration today announced it granted Emergency Use Authorization to Ortho Clinical Diagnostics' total antibody assay for COVID-19—the VITROS Immunodiagnostic Products Anti-SARS-CoV-2 Total Reagent Pack and Calibrators.

From Ortho-Clinical Diagnostics, Inc. 16 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

China with the world: COVID-19 experts dialogues - the 4th talk transcript

Q (Prof. Singer): What do you think about the comorbidities and the age of the patients in the treatment of COVID-19? Is the mortality higher in elderly patients as it is reported from recent papers?

From Mindray 15 Apr 2020

A desperate scramble as COVID-19 families vie for access to plasma therapy

Stephen Garcia's family is frantic. The auto body worker, just 32 years old, has been on a ventilator in a Los Angeles-area hospital for nearly two weeks, gravely ill with COVID-19, unresponsive — and unaware of the battle they're waging on his behalf.

15 Apr 2020

New blood test for antibodies in COVID-19 infected

The COVID-19 disease pandemic is raging across the world, costing tens of thousands of lives. Many countries have enforced widespread, if not universal lockdowns, to prevent the spread of the virus to new areas, carried by infected travelers.

14 Apr 2020

Translating COVID-19 into sound

News-Medical speaks to Professor Markus Buehler about his research into COVID-19 and how he has translated the SARS-CoV-2 virus into sound.

14 Apr 2020

California COVID-19 herd immunity theory debunked

A recent theory suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was doing the rounds in California as early as November 2019, infecting thousands undetected and leading to herd immunity, was debunked by experts from the scientific community. Antibody testing by a group of Stanford Medicine researchers was linked to the theory.

14 Apr 2020

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests.

13 Apr 2020

Milk allergy - is it overdiagnosed?

A new review published in the journal JAMA Pediatrics in April 2020 raises the concern that there may be a significant overdiagnosis of cow's milk allergy in babies and young children, stemming from the use of current medical recommendations.

13 Apr 2020

Missing COVID-19 antibodies suggest mystery immune response

Researchers at Shanghai Public Health Clinical Center have made important discoveries about the immune response among patients who have recovered from mild COVID-19 disease that could help to inform prevention and treatment methods, as well as improve the efficacy of community testing.

13 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020