Enzyme News and Research

RSS

HPV discovery could lead to new treatments for cervical cancer

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus that could lead to new treatments for cervical cancer and other cancers caused by the virus.

19 Dec 2018

Novel insight on inflammatory regulation could pave way for effective pain therapies

A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife.

19 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

Researcher conducts study to investigate peripheral blood markers of Alzheimer's disease

Β-amyloid formation, an indicative element of Alzheimer's disease, is a consequence of alternative expression of enzymes involved in the cleavage of amyloid precursor protein, leading to dementia in elderly populations.

17 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.

14 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasites, which can lay dormant for months or years as in the case of Plasmodium vivax. Researchers from Kanazawa University have successfully demonstrated that administration of a baculovirus virion completely eliminates liver-stage parasites in a mouse model via BV-induced fast-acting innate immunity.

13 Dec 2018

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug -- now in its earliest stages -- that can treat certain types of chronic pain without the addictive consequences of opioids.

12 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

New computer model predicts prostate cancer progression

An international team of cancer researchers from Denmark and Germany have used cancer patient data to develop a computer model that can predict the course of disease for prostate cancer.

11 Dec 2018

Study quantifies links between alcohol, drug use and violent deaths

A group of researchers at the University of São Paulo's Medical School (FM-USP) in Brazil recently published the results of a study on the links between alcohol and drug use and the occurrence of violent deaths.

7 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Researchers develop new molecular tool to decode sugar-protein attachments

Researchers at Johns Hopkins Medicine have developed a new molecular tool they call EXoO, which decodes where on proteins specific sugars are attached--a possible modification due to disease.

6 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

Protecting powerhouse of cells could provide better way to treat acute kidney injury

For the first time, scientists have described the body's natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren't getting enough blood or oxygen.

6 Dec 2018

New immuno-assay can detect small molecules with 50-fold greater sensitivity

As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed to detect levels of these molecules in order to monitor health and diagnose disease.

6 Dec 2018

Study reveals how the absence of Dna2 enzyme affects chromosome instability

Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication.

6 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

New therapeutic strategy is emerging for type 2 diabetes

Diabetes is a disease in which blood sugar levels are high over a prolonged period (hyperglycemia). In the case of type 2 diabetes, this phenomenon which is caused by a disruption of the glucose metabolism develops progressively and insidiously.

6 Dec 2018

Enzyme News and Research

HPV discovery could lead to new treatments for cervical cancer

Novel insight on inflammatory regulation could pave way for effective pain therapies

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

Researcher conducts study to investigate peripheral blood markers of Alzheimer's disease

Study finds epigenetic differences in the brains of individuals with schizophrenia

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

New discovery will improve the safety and predictability of CRISPR

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

New computer model predicts prostate cancer progression

Study quantifies links between alcohol, drug use and violent deaths

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

Researchers develop new molecular tool to decode sugar-protein attachments

Elevated hormone flags liver disease in mice with serious genomic disorder

Protecting powerhouse of cells could provide better way to treat acute kidney injury

New immuno-assay can detect small molecules with 50-fold greater sensitivity

Study reveals how the absence of Dna2 enzyme affects chromosome instability

Researchers create new light-activated tools for controlling neurons

New therapeutic strategy is emerging for type 2 diabetes

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo