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‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

At the Keystone Symposium "New Frontiers in Neurodegenerative Disease Research," held 4-7 February in Santa Fe, New Mexico, researchers explored the processes that lead to a variety of diseases, including Alzheimer's and Lou Gehrig's disease (amyotrophic lateral sclerosis, ALS).

7 Mar 2013

CALHM1 protein plays critical role in sweet, bitter and umami taste perception

Working with a multidisciplinary consortium of 19 researchers from nine institutions, Monell scientists have provided critical information to identify CALHM1, a channel in the walls of taste receptor cells, as a necessary component in the process of sweet, bitter, and umami (savory) taste perception.

7 Mar 2013

Research illuminates why stimulating environment may protect against Alzheimer's disease

"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease.

7 Mar 2013

mTORC2 plays key role in regulating memory formation

Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory - the introduction - and converted it into a long-term one.

7 Mar 2013

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections.

7 Mar 2013

New image-guided programming method can improve hearing in cochlear implant users

Imagine suddenly being able to hear the words and tone of the person across the table from you in a crowded restaurant when once you only heard overwhelming noise. Or speaking on the telephone with confidence because what you hear is now crisp and clear. Longtime cochlear implant users are reporting such dramatic improvements in their hearing, thanks to new image-guided programming methods developed by Vanderbilt University researchers.

7 Mar 2013

Drugs that inhibit buildup of acylcarnitines may block axonal degeneration

Anyone whose hand or foot has "fallen asleep" has an idea of the numbness and tingling often experienced by people with peripheral nerve damage. The condition also can cause a range of other symptoms, including unrelenting pain, stinging, burning, itching and sensitivity to touch.

6 Mar 2013

Neuromonitoring predicts functional outcome after rectal cancer surgery

Intraoperative neuromonitoring of the bladder and internal anal sphincter can accurately predict postsurgical urinary and anorectal function, research suggests.

6 Mar 2013

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

6 Mar 2013

Cognitive behavioral therapy brings relief to people with diabetic neuropathies, researchers find

Researchers at Boston University School of Medicine and VA Boston Healthcare System have found that cognitive behavioral therapy can help relieve pain for people with painful diabetic neuropathies.

5 Mar 2013

Children with low-risk retinoblastoma do not need postoperative chemotherapy

New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether. Avoiding chemotherapy spares patients from treatment side effects and long-term health risks, such as cardiovascular disease and development of a second cancer.

5 Mar 2013

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers supported by The ALS Association have discovered how mutations in new amyotrophic lateral sclerosis (ALS) genes cause not only ALS but also other diseases of the brain, muscle and bone.

4 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.

3 Mar 2013

Experience shows good results with secondary facelift surgery

Performed an average of a decade after initial facelift surgery, a "secondary" facelift can achieve similarly lasting results with a low complication rate, according to a paper in the March issue of Plastic and Reconstructive Surgery-, the official medical journal of the American Society of Plastic Surgeons (ASPS).

1 Mar 2013

DDR may help decrease cognitive and physical effects of multiple sclerosis

Studies have shown that the popular video game, Dance Dance Revolution (DDR), which requires players to coordinate their movements to the beat of music, may help improve balance and mobility in certain patient populations.

28 Feb 2013

ECGs show structural difference in brain connections among children with autism

A look at how the brain processes information finds a distinct pattern in children with autism spectrum disorders. Using EEGs to track the brain's electrical cross-talk, researchers from Boston Children's Hospital have found a structural difference in brain connections. Compared with neurotypical children, those with autism have multiple redundant connections between neighboring brain areas at the expense of long-distance links.

27 Feb 2013

Acupuncture with de qi improves facial muscle recovery in Bell palsy patients

Patients with Bell palsy who received acupuncture that achieves de qi, a type of intense stimulation, had improved facial muscle recovery, reduced disability and better quality of life, according to a randomized controlled trial published in CMAJ (Canadian Medical Association Journal).

26 Feb 2013

Nerve News and Research

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

CALHM1 protein plays critical role in sweet, bitter and umami taste perception

Research illuminates why stimulating environment may protect against Alzheimer's disease

mTORC2 plays key role in regulating memory formation

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

New image-guided programming method can improve hearing in cochlear implant users

Drugs that inhibit buildup of acylcarnitines may block axonal degeneration

Neuromonitoring predicts functional outcome after rectal cancer surgery

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

Cognitive behavioral therapy brings relief to people with diabetic neuropathies, researchers find

Children with low-risk retinoblastoma do not need postoperative chemotherapy

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Study identifies two gene mutations that lead to death of nerve cells in ALS

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

Experience shows good results with secondary facelift surgery

DDR may help decrease cognitive and physical effects of multiple sclerosis

ECGs show structural difference in brain connections among children with autism

Acupuncture with de qi improves facial muscle recovery in Bell palsy patients

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