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Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

29 Sep 2023

NCI-sponsored cancer clinical trials become more representative of broader patient population

Compared to the year 2000, a greater proportion of NCI-sponsored early-phase clinical trial participants in 2022 were older, from minority racial/ethnic groups, and lived in historically underrepresented regions of the U.S., according to a study presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

Sensors that monitor salivary metabolic changes to rapidly diagnose diabetes

A sensor for non-invasive glucose determination in body fluids such as saliva.

29 Sep 2023

Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

A comprehensive new analysis has found that nicotine e-cigarettes, varenicline and cytisine are the most effective options currently available for helping smokers quit long-term (going at least six months without smoking).

28 Sep 2023

Advancement of potential gene therapy could offer new hope for children with Batten disease

A new study shows that delivery of gene therapy to correct the gene mutations that cause CLN2 disease, or Batten disease, directly into the cerebrospinal fluid (CSF) has potential therapeutic effects.

28 Sep 2023

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

New study in Nature Medicine links yeast cells in the gastrointestinal tract to abnormal immune responses causing inflammation in Crohn's disease patients. The research suggests that these yeast-reactive T-cells could be a potential therapeutic target, offering new avenues for treatment.

27 Sep 2023

Loss of abdominal fat may be key to reversing prediabetes

Prediabetes is a condition that precedes type 2 diabetes and increases the risk of heart attack, kidney and eye disease, and several types of cancer. Currently, there is no approved drug therapy for prediabetes available.

27 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old - ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

Internet-delivered CBT may help reduce depressive symptoms in patients with multiple sclerosis

Major depressive disorder affects up to 50% of all individuals with multiple sclerosis (MS) at some point during their lifetime and can lead to lower quality of life, greater disease progression and higher mortality.

27 Sep 2023

More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study published in the September 27, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Sep 2023

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine.

27 Sep 2023

Obesity linked to worse menopause symptoms and less effective hormone therapy

Obesity has already been associated with a number of adverse health conditions and can interfere with a person's quality of life.

27 Sep 2023

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Rice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique in rodents, and their findings suggest that the efficiency of gene delivery improves within each targeted site when more sites are opened.

27 Sep 2023

Therapy News and Research

Monocyte-derived macrophages play a crucial role in liver regeneration

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

NCI-sponsored cancer clinical trials become more representative of broader patient population

Sensors that monitor salivary metabolic changes to rapidly diagnose diabetes

Insights and new directions in basic, clinical research into neurodegenerative diseases

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

Advancement of potential gene therapy could offer new hope for children with Batten disease

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

Loss of abdominal fat may be key to reversing prediabetes

Researchers develop new way to boost immune cells' ability to fight TB

Internet-delivered CBT may help reduce depressive symptoms in patients with multiple sclerosis

More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

Study details the key role played by neutrophils in ensuring survival of brain cancers

Blocking Notch signaling pathway could reverse age-related bone loss

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

Obesity linked to worse menopause symptoms and less effective hormone therapy

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Psychological causes and treatments for erectile dysfunction often overlooked, researchers say

Promising potential of probiotics and their byproducts for targeting antibiotic-resistant bacteria

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

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