B Cell News and Research

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Possible new therapy for lymphoma and leukemia patients

Marty Holmes, a landscaper from Stockton, Calif., had never heard of a regulatory T cell before his doctor suggested that it could be the key to helping him survive his cancer.

28 Sep 2005

Dengue and other viruses may have developed tricks that let them reproduce inside macrophages

A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells. Instead, the antibody somehow stops the infectious process at a later point.

28 Sep 2005

Discovery may lead to development of more effective antibiotics

Researchers at the Georgia Institute of Technology and the John Innes Centre in the United Kingdom have uncovered a mechanism with which disease-causing bacteria may thwart the body's natural defense responses. The findings, which could ultimately lead to the development of more effective antibiotics, appear in the September 29, 2005 issue of the journal Nature.

28 Sep 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Scientists studying the humble fruit fly have found a family of proteins that enhances the sensitivity of a cell to a hormone that can trigger abnormal growth and cancer. Their discovery could lead to a completely new approach to tackling some cancers and the development of new drugs to stop uncontrolled growth in a wide variety of tumour cells.

28 Sep 2005

100 year old technology to fight MRSA

A technique that has been around for more than one hundred years is being used in new research as a way of killing methicillin-resistant Staphylococcus aureus (MRSA) using light. The research to be reported today at the British Pharmaceutical Conference in Manchester, is being undertaken by researchers from Queen's University Belfast.

28 Sep 2005

From aircraft aerodynamics to improved heart implants

At first glance airplane wings and human hearts have little in common, but, say a team of European researchers, a technology used to measure airflow over wings can now be used to help keep hearts in working order.

28 Sep 2005

Clostridium botulinum exposed

A discovery by Institute of Food Research (IFR) scientists is set to improve the food industry’s ability to predict foodborne botulism.

28 Sep 2005

Possible therapy that could control blood pressure

A newly developed virus that introduces a blood pressure-lowering gene into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take gene therapy for the disorder a step closer to reality, said researchers at Baylor College of Medicine in a report released online in the Proceedings of the National Academy of Sciences.

27 Sep 2005

Equine flu virus jumps to dogs

A Cornell University virologist has isolated a highly contagious equine flu virus that is spreading a sometimes-fatal respiratory flu among dogs, and is responsible for a major dog-flu outbreak in New York state. There is no evidence that the virus could infect people.

27 Sep 2005

New virus-based gene therapy delivery system to help fight cancer

A Mayo Clinic research team has devised a new virus-based gene therapy delivery system to help fight cancer. Researchers say their findings will help overcome hurdles that have hindered gene therapy cancer treatments.

27 Sep 2005

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

In a significant advance toward understanding a perplexing and painful neurological disorder, an international team of researchers has discovered gene mutations associated with an inherited chronic pain and weakness syndrome known as hereditary neuralgic amyotrophy (also called HNA).

27 Sep 2005

Possibility of tailored treatments for addiction based on how a person's genes behave

Scientists have learned how a genetic variation long suspected in making some people susceptible to alcoholism and narcotic drug addiction actually does so.

27 Sep 2005

Seaweed extract, alginate, could be used to increase the fibre content of junk food

The highly-fibrous seaweed extract, alginate, could be used to increase the fibre content of cakes, burgers and other types of food which usually contain large amounts of fat and a low degree of healthy nutrients, say the team.

27 Sep 2005

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

Scientists in Japan have found a way to improve on a promising diabetes treatment. In the October 3 issue of The Journal of Experimental Medicine, Masaru Taniguchi and colleagues report that transplanted insulin-producing cells survive better when the activation of a specific type of immune cell is blocked.

27 Sep 2005

Temperature can regulate the circadian clock in zebrafish

The biological clock controls the circadian rhythms of a wide range of physiological and behavioral processes, from fluctuating hormone levels to sleep - wake cycles and feeding patterns.

27 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Water management is the key to regulating cell volume

...says Dutch researcher Bas Tomassen. He investigated the uptake and secretion of water by the plasma membrane of animal and human cells.

27 Sep 2005

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

B Cell News and Research

Possible new therapy for lymphoma and leukemia patients

Dengue and other viruses may have developed tricks that let them reproduce inside macrophages

Discovery may lead to development of more effective antibiotics

New Stat1 and interferon findings

Fruit fly discovery could lead to a completely new approach to tackling some cancers

100 year old technology to fight MRSA

From aircraft aerodynamics to improved heart implants

Clostridium botulinum exposed

Possible therapy that could control blood pressure

Equine flu virus jumps to dogs

New virus-based gene therapy delivery system to help fight cancer

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

Possibility of tailored treatments for addiction based on how a person's genes behave

Seaweed extract, alginate, could be used to increase the fibre content of junk food

Transplanted insulin-producing cells survive better when the activation of NKT cells are blocked

Temperature can regulate the circadian clock in zebrafish

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Water management is the key to regulating cell volume

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

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