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Wireless magnetogenetic approach could be used to treat motor dysfunction in people with Parkinson’s disease

Electrical deep brain stimulation (DBS) is a well-established method for treating disordered movement in Parkinson's disease.

18 Jan 2024

Monell study: Unraveling the brain's wiring for fat and sugar cravings

Understanding why we overeat unhealthy foods has been a long-standing mystery. While we know food's strong power influences our choices, the precise circuitry in our brains behind this is unclear.

18 Jan 2024

Machine learning algorithm decodes mutations driving cancer treatment resistance

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, scientists at University of California San Diego School of Medicine leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy.

18 Jan 2024

MIT study reveals consistent oscillation patterns across brain cortex layers

Throughout the brain's cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope.

18 Jan 2024

DNA origami used to unveil novel Notch receptor activation pathway

Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way.

18 Jan 2024

Cord blood-derived CAR NK cell therapy targeting CD19 shows promise for treating patients with B-cell malignancies

Researchers from The University of Texas MD Anderson Cancer Center reported promising results in a Phase I/II trial of 37 patients with relapsed or refractory B-cell malignancies who were treated with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK) cell therapy targeting CD19.

18 Jan 2024

New targeted therapy eliminates cancer with zero side effects

Johannes Karges develops anti-cancer agents that work in a targeted manner, rather than adversely affecting the entire body.

18 Jan 2024

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells.

18 Jan 2024

New technique provides an unprecedented view inside the cell's control center

The cell nucleus is considered to be the control center of vital cellular processes, but its material properties continue to puzzle scientists.

18 Jan 2024

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Researchers investigate the mechanism responsible for amphotericin B tolerance of Cryptococcus neoformans.

18 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

New bioengineered strategy shows potential for treating ulcerative colitis

By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.

17 Jan 2024

ALS progression linked to mitochondria-associated membrane-ER disconnection

Researchers at Nagoya University in Japan have discovered a relationship between the progression of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the disruption of mitochondria-associated membranes (MAM), the contact point between the mitochondria and the endoplasmic reticulum (ER) of the cell.

17 Jan 2024

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Study investigates the impact of helminth infection on COVID-19 mRNA vaccine efficacy, revealing that while antibody responses remain largely unaffected, T-cell responses are significantly impaired, particularly against Omicron variants.

17 Jan 2024

New vaccine turns preexisting flu immunity into COVID-19 weapon

After COVID vaccination, it usually takes weeks for our bodies to develop protective antibody responses.

17 Jan 2024

Innovative computational tool unearths hidden cancer targets for immunotherapy

An innovative computational tool dubbed "SNAF" may help the research world bring the emerging promise of cancer immunotherapy to a wider range of patients, according to a study published Jan. 17, 2024, in Science Translational Medicine.

17 Jan 2024

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

Scientists have grown 'mini-placentas' in the lab and used them to shed light on how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

RBMX protein emerges as key player in cancer progression and immunotherapy response

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response."

17 Jan 2024

Decoding blood cancer secrets to optimize CAR T therapy

Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR T can be used as an earlier treatment option.

17 Jan 2024

Study highlights a potential new strategy to target triple-negative breast cancer

Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly.

17 Jan 2024

B Cell News and Research

Wireless magnetogenetic approach could be used to treat motor dysfunction in people with Parkinson’s disease

Monell study: Unraveling the brain's wiring for fat and sugar cravings

Machine learning algorithm decodes mutations driving cancer treatment resistance

MIT study reveals consistent oscillation patterns across brain cortex layers

DNA origami used to unveil novel Notch receptor activation pathway

Cord blood-derived CAR NK cell therapy targeting CD19 shows promise for treating patients with B-cell malignancies

New targeted therapy eliminates cancer with zero side effects

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

New technique provides an unprecedented view inside the cell's control center

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

New bioengineered strategy shows potential for treating ulcerative colitis

ALS progression linked to mitochondria-associated membrane-ER disconnection

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

New vaccine turns preexisting flu immunity into COVID-19 weapon

Innovative computational tool unearths hidden cancer targets for immunotherapy

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

RBMX protein emerges as key player in cancer progression and immunotherapy response

Decoding blood cancer secrets to optimize CAR T therapy

Study highlights a potential new strategy to target triple-negative breast cancer

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