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California Initiative to Advance Precision Medicine selects two demonstration projects

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.

4 Aug 2015

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Researchers at the Johns Hopkins University School of Medicine, Johns Hopkins University Department of Chemical and Biomolecular Engineering, and Federal University of Rio de Janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue — proving the concept, they say, that therapeutic genes may one day be delivered directly to the lungs to the levels sufficient to treat cystic fibrosis (CF), chronic obstructive pulmonary disease, asthma and other life-threatening lung diseases.

4 Aug 2015

Shire acquires Foresight Biotherapeutics for $300 million

Shire plc announced today that it has acquired New York-based, privately held Foresight Biotherapeutics Inc. for $300 million.

3 Aug 2015

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Immunotherapy using monoclonal antibodies is a promising treatment strategy, and it might now be within reach: American scientists have successfully prepared an oligosaccharide enterobacterial antigen for which a monoclonal antibody has been developed. The study is published in the journal Angewandte Chemie.

31 Jul 2015

Study shows link between liver-produced molecules, pneumonia susceptibility during sepsis

New evidence highlights the importance of the liver in immunity against bacterial pneumonia. The study is the first of its kind to directly show such a link between liver-produced molecules and pneumonia susceptibility during sepsis.

31 Jul 2015

UIC, Northwestern University researchers create first artificial ribosome

Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell. The engineered ribosome may enable the production of new drugs and next-generation biomaterials and lead to a better understanding of how ribosomes function.

30 Jul 2015

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

It's one thing to grow bacteria in a test tube, perform a screen in the lab, and find a mutation in the pathogen's genes. It's a whole other thing, and much rarer, to find the exact same mutation in nature--in this case, in E. coli in urine samples from some 500 patients suffering from relapsing urinary tract infections.

30 Jul 2015

Researchers uncover groundbreaking evidence for developing vaccine to prevent middle ear infections

Researchers from Griffith University's Institute for Glycomics, together with the Nationwide Children's Hospital in Ohio, have uncovered groundbreaking evidence to help vaccine developers prevent middle ear infections.

30 Jul 2015

Intestinal bacteria play crucial role in inducing anxiety, depression

Scientists from the Farncombe Family Digestive Health Research Institute at McMaster University have discovered that intestinal bacteria play an important role in inducing anxiety and depression.

29 Jul 2015

Cincinnati Children's doctors remind parents about the importance of immunizing kids before sending them to school

Doctors at Cincinnati Children's Hospital Medical Center want to remind parents about the importance of immunizing their children when preparing to send their children back to school.

28 Jul 2015

Wayne State leads landmark study that examines clinical use of polymyxin B to treat superbugs

With the decline of the development of new antibiotics due to the complexity and expense of discovering them, there has been a rapid growth of antibiotic resistant pathogens that is one of the leading causes of death. With the help of a nearly $4.9 million, 5-year grant from the National Institute for Allergy and Infectious Diseases of the National Institutes of Health, Wayne State University School of Medicine researchers are leading a landmark multi-center, international study that will provide essential information to clinicians for use of polymoxin B in critically ill patients where no other treatments will work.

28 Jul 2015

Landmark study to provide critical information for optimized use of polymyxin B in critically ill patients

28 Jul 2015

Study finds strong link between diabetes and TB in tropical Australia

A 20-year study by James Cook University scientists has found a strong link between diabetes and tuberculosis in tropical Australia.

28 Jul 2015

Hand washing tips to protect against many infections

As the beginning of the school year approaches, parents need to remind their children about the importance of hand washing. Every day people touch several surfaces including books, desks, door knobs, sink handles, and other people and many of them harbor germs like bacteria and viruses that can cause illnesses.

27 Jul 2015

New findings unlock clues to disease protection

When disease-resistant rice is invaded by disease-causing bacteria, a small protein produced by the bacteria betrays the invader. Upon recognizing that protein, the rice plants sense that a microbial attack is underway and are able to mount an immune response to fend off bacterial infection, reports a research team led by the University of California, Davis.

25 Jul 2015

Mix of bacteria living in guts may band together to ward off dangerous infections

Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests.

24 Jul 2015

SutroVax completes $22 million Series A financing

SutroVax, a recently established biopharmaceutical vaccine company, today announced the completion of a $22 million Series A financing. SutroVax is developing vaccines for infectious disease targets, with an initial emphasis on best-in-class conjugate vaccines, using an exclusive license to Sutro Biopharma's Xpress CF and Xpress CF+ platforms for cell free protein synthesis and site-specific conjugation respectively.

23 Jul 2015

Retail meat harbors disease-causing Klebsiella pneumoniae, shows new study

Chicken, turkey and pork sold in grocery stores harbors disease-causing bacteria known as Klebsiella pneumoniae, according to a new study. The research, which was published online today in the journal Clinical Infectious Diseases, shows that contaminated meat may be an important source of human exposure to Klebsiella.

23 Jul 2015

Expanded use for IntelliCap with further CE Mark for aspiration of fluids

The small, pill-shaped IntelliCap wireless medical device is opening up research opportunities into the impact of the small intestine microbiota on health and disease. For the first time, scientists have been able to obtain and analyse samples of the small intestine’s microbiome in a non-invasive way.

21 Jul 2015

Duke study finds that gut worms can protect babies' brains from chronic inflammation

A Duke University study in rats finds that gut worms can protect babies' brains from long-term learning and memory problems caused by newborn infections.

21 Jul 2015

Bacterial News and Research

California Initiative to Advance Precision Medicine selects two demonstration projects

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Shire acquires Foresight Biotherapeutics for $300 million

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Study shows link between liver-produced molecules, pneumonia susceptibility during sepsis

UIC, Northwestern University researchers create first artificial ribosome

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

Researchers uncover groundbreaking evidence for developing vaccine to prevent middle ear infections

Intestinal bacteria play crucial role in inducing anxiety, depression

Cincinnati Children's doctors remind parents about the importance of immunizing kids before sending them to school

Wayne State leads landmark study that examines clinical use of polymyxin B to treat superbugs

Landmark study to provide critical information for optimized use of polymyxin B in critically ill patients

Study finds strong link between diabetes and TB in tropical Australia

Hand washing tips to protect against many infections

New findings unlock clues to disease protection

Mix of bacteria living in guts may band together to ward off dangerous infections

SutroVax completes $22 million Series A financing

Retail meat harbors disease-causing Klebsiella pneumoniae, shows new study

Expanded use for IntelliCap with further CE Mark for aspiration of fluids

Duke study finds that gut worms can protect babies' brains from chronic inflammation

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