Nerve News and Research

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Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

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14 Mar 2013

VCP gene mutations cause neurological conditions including IBMPFD and ALS

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS).

14 Mar 2013

H1N1 flu vaccination associated with small excess risk of acquiring Guillain-Barré syndrome, but benefits outweigh risks

A meta-analysis of safety data gathered during the 2009 H1N1 vaccination programme in the US has established that the vaccination was associated with a small excess risk – about 1.6 extra cases per one million people vaccinated – of acquiring Guillain-Barré syndrome, a disorder of the nervous system which can result in temporary or more long-lasting paralysis and infrequently death. The authors conclude that the benefits of the 2009 H1N1 vaccination campaign greatly outweighed the risks.

14 Mar 2013

Stimulating brain using magnetic stimulation may improve cognitive function, say scientists

Cognitive impairments are disabling for individuals with schizophrenia, and no satisfactory treatments currently exist. These impairments affect a wide range of cognition, including memory, attention, verbal and motor skills, and IQ.

14 Mar 2013

New procedure to treat pseudotumor cerebri

A team of interventional neuroradiologists and neurosurgeons at Johns Hopkins reports wide success with a new procedure to treat pseudotumor cerebri, a rare but potentially blinding condition marked by excessive pressure inside the skull, caused by a dangerous narrowing of a vein located at the base of the brain.

13 Mar 2013

MGH investigators identify new disease that causes widespread chronic pain in children

Massachusetts General Hospital (MGH) investigators have described what may be a newly identified disease that appears to explain some cases of widespread chronic pain and other symptoms in children and young adults.

13 Mar 2013

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms.

13 Mar 2013

Combination of INF and glatiramer acetate does not reduce MS progression

A recent clinical trial found that interferonβ-1a (INF) and glatiramer acetate (GA), two of the most commonly prescribed drugs for multiple sclerosis (MS), provide no additional clinical benefit when taken together.

12 Mar 2013

Buphenyl may protect memory and prevent progression of Alzheimer's

Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease.

12 Mar 2013

Researchers develop new approach to screening potential treatments for Alzheimer's disease

According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million).

11 Mar 2013

Researchers identify new mechanism in onset of motor neuron diseases

The British astrophysicist Stephen Hawking is likely to be the world's most famous person living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ALS is a progressive disease affecting motor neurons, nerve cells that control muscle function, and nearly always leads to death.

11 Mar 2013

GENIE public engagement lectures to take place on Mar. 12

If you have ever wondered why a curry feels hot, or about the risks of inherited disease, two eminent experts will give you an answer at a University of Leicester public event.

8 Mar 2013

Boosting hypocretin could elevate both mood and alertness in humans

What makes us happy? Family? Money? Love? How about a peptide? The neurochemical changes underlying human emotions and social behavior are largely unknown. Now though, for the first time in humans, scientists at UCLA have measured the release of a specific peptide, a neurotransmitter called hypocretin, that greatly increased when subjects were happy but decreased when they were sad.

8 Mar 2013

Researchers identify role of Merlin in regulating integrity of axons

One in 25,000 people worldwide is affected by neurofibromatosis type 2 (NF2), a condition where the loss of a tumour suppressor called Merlin results in multiple tumours in the brain and nervous system.

7 Mar 2013

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

At the Keystone Symposium "New Frontiers in Neurodegenerative Disease Research," held 4-7 February in Santa Fe, New Mexico, researchers explored the processes that lead to a variety of diseases, including Alzheimer's and Lou Gehrig's disease (amyotrophic lateral sclerosis, ALS).

7 Mar 2013

CALHM1 protein plays critical role in sweet, bitter and umami taste perception

Working with a multidisciplinary consortium of 19 researchers from nine institutions, Monell scientists have provided critical information to identify CALHM1, a channel in the walls of taste receptor cells, as a necessary component in the process of sweet, bitter, and umami (savory) taste perception.

7 Mar 2013

Research illuminates why stimulating environment may protect against Alzheimer's disease

"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease.

7 Mar 2013

mTORC2 plays key role in regulating memory formation

Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory - the introduction - and converted it into a long-term one.

7 Mar 2013

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections.

7 Mar 2013

New image-guided programming method can improve hearing in cochlear implant users

Imagine suddenly being able to hear the words and tone of the person across the table from you in a crowded restaurant when once you only heard overwhelming noise. Or speaking on the telephone with confidence because what you hear is now crisp and clear. Longtime cochlear implant users are reporting such dramatic improvements in their hearing, thanks to new image-guided programming methods developed by Vanderbilt University researchers.

7 Mar 2013

Nerve News and Research

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

VCP gene mutations cause neurological conditions including IBMPFD and ALS

H1N1 flu vaccination associated with small excess risk of acquiring Guillain-Barré syndrome, but benefits outweigh risks

Stimulating brain using magnetic stimulation may improve cognitive function, say scientists

New procedure to treat pseudotumor cerebri

MGH investigators identify new disease that causes widespread chronic pain in children

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

Combination of INF and glatiramer acetate does not reduce MS progression

Buphenyl may protect memory and prevent progression of Alzheimer's

Researchers develop new approach to screening potential treatments for Alzheimer's disease

Researchers identify new mechanism in onset of motor neuron diseases

GENIE public engagement lectures to take place on Mar. 12

Boosting hypocretin could elevate both mood and alertness in humans

Researchers identify role of Merlin in regulating integrity of axons

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

CALHM1 protein plays critical role in sweet, bitter and umami taste perception

Research illuminates why stimulating environment may protect against Alzheimer's disease

mTORC2 plays key role in regulating memory formation

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

New image-guided programming method can improve hearing in cochlear implant users

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