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New study investigates role of rare gene variants in IBD risk for African Americans

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

15 Nov 2023

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

Amelia Lavenski's seizure-free journey with the ketogenic diet

Amelia Lavenski is a 4-year-old girl from Anne Arundel County, Maryland, who has a bright personality and loves laughing and Mickey Mouse.

15 Nov 2023

World-first type 1 diabetes risk screening study in adults opens for recruitment

A world-first research programme led by the University of Bristol that will identify adults at high risk of developing type 1 diabetes opens for recruitment.

15 Nov 2023

Novel robotic system accurately measures arm usage in stroke patients

Stroke is a leading cause of long-term disability worldwide. Each year more than 15 million people worldwide have strokes, and three-quarters of stroke survivors will experience impairment, weakness and paralysis in their arms and hands.

15 Nov 2023

New evidence-based clinical practice guidelines to address peripartum depression

Pregnancy and the first year postpartum - referred to as the peripartum period - are a period of tremendous physiological, psychological, and social changes in a woman's life.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

The unusual way a Catholic health system is wielding an abortion protest law

A Catholic hospital system is suing several California patients and their advocates because the patients allegedly refused to be discharged.

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Regenerative medicine takes leap forward with nasal cartilage-derived cartilage grafts

The Department of Biomedicine at the University of Basel and the University Hospital Basel, today announced that it delivered the first surgical procedure to treat Osteoarthritis (OA) in humans.

15 Nov 2023

Plant-based diets regulate gestational weight gain in early pregnancy

The study in the European Journal of Clinical Nutrition found that Iranian pregnant women adhering to plant-based diets had a lower risk of inadequate gestational weight gain, with no significant association observed between these diets and excessive gestational weight gain.

14 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Aspirin avoidance improves clinical outcomes in patients with advanced heart failure

Left ventricular assist devices (LVADs) are pumps that are used to circulate blood in patients with weakened hearts due to advanced heart failure. Mechanical stress on these implants can make patients susceptible to blood clots, and patients are required to take anti-clotting medications including vitamin-k antagonists (VKA) and aspirin.

14 Nov 2023

Gene therapy for rare diseases: A decade of progress and remaining challenges

A new review article in the peer-reviewed journal Human Gene Therapy summarizes the significant milestones in the development of gene therapy medicinal products that have facilitated the treatment of a significant number of rare diseases.

14 Nov 2023

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Cannabidiol (CBD) is marketed by some suppliers as a painkiller, e.g. for osteoarthritis of the knee. Animal experiments have shown that the substance, which is extracted from the hemp plant, has an anti-inflammatory and pain-relieving effect in arthritis.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Therapy News and Research

New study investigates role of rare gene variants in IBD risk for African Americans

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

Amelia Lavenski's seizure-free journey with the ketogenic diet

World-first type 1 diabetes risk screening study in adults opens for recruitment

Novel robotic system accurately measures arm usage in stroke patients

New evidence-based clinical practice guidelines to address peripartum depression

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

The unusual way a Catholic health system is wielding an abortion protest law

New research explores the unique effects of ADHD medications on Drosophila brain cells

Regenerative medicine takes leap forward with nasal cartilage-derived cartilage grafts

Plant-based diets regulate gestational weight gain in early pregnancy

New approach to CAR T cell therapy may extend treatment effectiveness

Study reveals mechanisms underlying non-suppressible HIV viremia

Aspirin avoidance improves clinical outcomes in patients with advanced heart failure

Gene therapy for rare diseases: A decade of progress and remaining challenges

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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