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Researchers find a promising drug candidate for the treatment of ALS

A research group at the University of Helsinki and its partners have found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS).

22 Sep 2023

Using kinase inhibitors in subsets of colorectal cancer patients

A new editorial paper was published in Oncoscience (Volume 10) on June 27, 2023, entitled, "Kinase-targeted therapy in subsets of colorectal cancer."

22 Sep 2023

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Macrophages are little cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions.

22 Sep 2023

New science committee to support One Medicine research at Humanimal Trust

Humanimal Trust, the charity founded in 2014 by orthopaedic veterinary surgeon, Professor Noel Fitzpatrick, has announced a new Committee of independent advisors, made up of leading human and animal health professionals, academics and researchers from around the world.

22 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Multipronged gene therapy restores walking in mice after complete spinal cord injury

When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function.

21 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

AI slashes stroke treatment time and saves lives in new study

AI-driven software significantly speeds up the detection of large vessel occlusion in stroke patients, reducing treatment time and potentially improving outcomes. The automated system was linked to a 60% drop in mortality rates in a clinical trial across four comprehensive stroke centers.

21 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Researchers develop new approach to fighting chemo-resistant small cell lung cancer

Small cell lung cancer accounts for about 15 percent of all diagnosed lung cancers and is still associated with a high mortality rate.

21 Sep 2023

Digital vision training may not be an effective treatment for amblyopia in children

In the "ThemenCheck Medizin" procedure offered by the German Institute for Quality and Efficiency in Health Care (IQWiG), interested members of the public can submit proposals for the assessment of medical procedures and technologies.

21 Sep 2023

Is menopausal hormone therapy associated with non-alcoholic fatty liver disease?

The effects of menopausal hormone therapy on non-alcoholic fatty liver disease.

21 Sep 2023

Can deep brain stimulation unlock the cure for severe depression?

A multidisciplinary team of clinicians, engineers, and neuroscientists has identified a unique biomarker in the brain that indicates recovery from treatment-resistant depression, utilizing deep brain stimulation (DBS) and artificial intelligence. The discovery, which allows for real-time monitoring and tailoring of treatment, could revolutionize the approach to managing severe forms of depression.

21 Sep 2023

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual.

20 Sep 2023

Cognitive behavioral therapy can significantly reduce the burden of fibromyalgia

Patients living with fibromyalgia (FM) – a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog – often find limited treatment options and a scarcity of explanations for their symptoms.

20 Sep 2023

Cognitive-behavioral therapy reduces the interfering effects of fibromyalgia pain

In a recent randomized clinical trial of patients with fibromyalgia, cognitive-behavioral therapy (CBT) - which uses structured techniques to alter distorted thoughts and negative moods - was superior to a matched education treatment in reducing the interfering effects of pain and other aspects of fibromyalgia on daily living.

20 Sep 2023

Uncontrolled hypertension wreaks havoc on global health and economies

The World Health Organization's recent report underscores the global health and economic crisis posed by uncontrolled hypertension, affecting one in five people worldwide. The study calls for urgent, coordinated government action, emphasizing that effective hypertension management could prevent millions of deaths and offer an 18-to-1 return on investment.

20 Sep 2023

Uromodulin levels linked to kidney failure risk

Prior studies of uromodulin, the most abundant protein in urine, and kidney disease have focused primarily on urinary uromodulin levels.

20 Sep 2023

Therapy News and Research

Researchers find a promising drug candidate for the treatment of ALS

Using kinase inhibitors in subsets of colorectal cancer patients

Researchers develop novel ultrasound imaging technique to view macrophages in real time

New science committee to support One Medicine research at Humanimal Trust

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Multipronged gene therapy restores walking in mice after complete spinal cord injury

Pitt launches trial to test interventions for life-threatening bleeding in injured children

AI slashes stroke treatment time and saves lives in new study

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Researchers develop new approach to fighting chemo-resistant small cell lung cancer

Digital vision training may not be an effective treatment for amblyopia in children

Is menopausal hormone therapy associated with non-alcoholic fatty liver disease?

Can deep brain stimulation unlock the cure for severe depression?

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Cognitive behavioral therapy can significantly reduce the burden of fibromyalgia

Cognitive-behavioral therapy reduces the interfering effects of fibromyalgia pain

Uncontrolled hypertension wreaks havoc on global health and economies

Uromodulin levels linked to kidney failure risk

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