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Steroid hormones could provide new insight into age-related bone loss

A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.

15 Sep 2017

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Salk Institute scientists have discovered that an interaction between two key proteins helps regulate and maintain the cells that produce neurons.

15 Sep 2017

Heidelberg researchers gain new insights into formation of blood vessels

New insights into the development of the vascular system: researchers in the team of Dr Carmen Ruiz de Almodóvar of the Heidelberg University Biochemistry Center have discovered a crucial biological step that regulates the formation of blood vessels.

15 Sep 2017

Brain rewiring due to dopamine loss may be source of impaired movement in Parkinson's disease

The brain's own mechanisms for dealing with the loss of dopamine neurons in Parkinson's disease may be a source of the disorder's abnormal movement, according to a Northwestern Medicine study published in Neuron.

14 Sep 2017

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

Using a microscope invented at the Marine Biological Laboratory (MBL), a collaborative team of biologists, instrument developers, and computational scientists has for the first time measured the density of a relatively inscrutable, highly condensed form of chromosomal material that appears in the cells of human beings and other eukaryotes.

13 Sep 2017

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Scientists at The Scripps Research Institute have found a new approach to the "reprogramming" of ordinary adult cells into stem cells.

12 Sep 2017

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Penn researcher wins National Cancer Institute Outstanding Investigator Award

M. Celeste Simon, PhD, who studies cancer cell metabolism, tumor immunology, and the influence of oxygen availability and deprivation on tumor growth, has been given a National Cancer Institute Outstanding Investigator Award.

8 Sep 2017

Study provides first structural glimpse of circadian clock's molecular machinery

Scientists have long known that circadian clocks- biochemical oscillators that control physiology, metabolism and behavior on a roughly 24-hour cycle- are present in all forms of life, including animals, plants, fungi and some types of bacteria. However, the molecular mechanisms that "run" these systems remain largely unknown.

7 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

Kessler scientists link cognitive fatigue in individuals with TBI to caudate activation

Kessler Foundation researchers have authored a new article that further elucidates the mechanisms for cognitive fatigue, a disabling symptom that affects many individuals after traumatic brain injury (TBI).

4 Sep 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases - including cancer, diabetes and HIV - faster and cheaper to develop, and more customizable.

30 Aug 2017

Study provides better understanding of how estrogen regulates gene expression

Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in specific order.

24 Aug 2017

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Mitochondria, the tiny structures inside our cells that generate energy, may play a key role in autism spectrum disorders (ASD).

23 Aug 2017

Northwestern Medicine scientists develop novel method to track HIV infection

Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions -- infectious particles -- to be connected to infectivity.

18 Aug 2017

Study provides insight into development of red blood cells

Every cell in the body, whether skin or muscle or brain, starts out as a generic cell that acquires its unique characteristics after undergoing a process of specialization. Nowhere is this process more dramatic than it is in red blood cells.

18 Aug 2017

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

Biomedical engineers have grown miniature human blood vessels that exhibit many of the symptoms and drug reactions associated with Hutchinson-Gilford Progeria Syndrome -- an extremely rare genetic disease that causes symptoms resembling accelerated aging in children.

16 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Scientists create stem cell-based model of rare inherited neurological condition

An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS).

11 Aug 2017

Habitual players of action video games have less grey matter in their brain, study reveals

Neuroscientists should think twice before getting patients to play video games as a way to boost their brain power, a new study conducted at Université de Montréal suggests. Why? Because in many cases, gaming can do more harm than good.

8 Aug 2017

Cell Nucleus News and Research

Steroid hormones could provide new insight into age-related bone loss

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Heidelberg researchers gain new insights into formation of blood vessels

Brain rewiring due to dopamine loss may be source of impaired movement in Parkinson's disease

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Old lab technique helps researchers better understand circular DNA

Penn researcher wins National Cancer Institute Outstanding Investigator Award

Study provides first structural glimpse of circadian clock's molecular machinery

Scientists show how receptors for drugs act inside cells

Kessler scientists link cognitive fatigue in individuals with TBI to caudate activation

New biomedical tool using nanoparticles could improve therapies for many diseases

Study provides better understanding of how estrogen regulates gene expression

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Northwestern Medicine scientists develop novel method to track HIV infection

Study provides insight into development of red blood cells

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Scientists create stem cell-based model of rare inherited neurological condition

Habitual players of action video games have less grey matter in their brain, study reveals

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