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Western diet weakens the gut’s nervous system through iron-dependent damage

A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.

10 Jun 2026

Researchers uncover immune loop driving Sjögren's disease progression

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

10 Jun 2026

More movement and less sitting benefit pregnant women

Women who engage in light physical activity and lessen their sedentary time may significantly reduce the risk of key health problems during pregnancy, according to a new University of Iowa-led study.

10 Jun 2026

Many middle-aged Americans lack basic health literacy

OK, Boomers, it turns out Millennials and Gen X also struggle navigating the often-confusing and overwhelming world of health care.

10 Jun 2026

Low blood pressure shows strongest link to Alzheimer's disease

Numerous types of cardiovascular disease and CVD risk factors were linked to a higher risk of Alzheimer's disease, with low blood pressure showing the strongest connection, according to a new analysis published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Jun 2026

Social anxiety disorder now affects one in seven Canadian adults

A new Canadian study has found that social anxiety disorder (SAD) now affects nearly 1 in 7 adults - a 71% increase since 2002 - making it one of the most common mental health challenges in the country.

10 Jun 2026

Study finds indoor cats do not trigger child asthma flares

Asthma is the most common chronic disease and one of the main causes of hospitalization among children. The Global Asthma Network has estimated that its global prevalence is 9.1% for children and 11.0% for adolescents, but this percentage varies greatly between countries, regions, and environments.

10 Jun 2026

Oral swab detects hidden inflammation in rare lung disease

Researchers at UTHealth Houston have identified different types of hidden systemic inflammation in patients with primary ciliary dyskinesia, even when they are not experiencing acute illness.

9 Jun 2026

Excess weight identified as key driver for cardiovascular-kidney-metabolic syndrome

The first-ever clinical guideline for cardiovascular-kidney-metabolic syndrome, or CKM syndrome, identifies excess weight, especially in the abdomen, as a key driver for the syndrome. T

9 Jun 2026

New clinical guidelines target interconnected heart, kidney and metabolic risks

The American Heart Association and the American College of Cardiology, along with two other leading medical organizations have developed the first-ever guideline aimed at preventing and managing cardiovascular-kidney-metabolic (CKM) syndrome, an interconnected set of health conditions that significantly increase the risk of multiorgan complications and negative cardiovascular outcomes.

9 Jun 2026

New study frames altered protein modifications as cancer drivers

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

9 Jun 2026

Advanced MRI scans predict chronic kidney disease in patients undergoing nephrectomy

An investigator at the Icahn School of Medicine at Mount Sinai has received international recognition for innovative imaging research that may help physicians identify patients at increased risk of chronic kidney disease (CKD) before they undergo surgery for kidney tumors.

9 Jun 2026

AI screening tool increases diabetic eye exam referrals for African Americans

In a study exploring how an AI-assisted diagnostic tool shaped care for underserved populations at multiple community-based primary care sites, investigators at the Wilmer Eye Institute, Johns Hopkins Medicine found that African American patients with diabetes were more likely to receive a diabetic eye exam referral if screened by an AI tool.

9 Jun 2026

New geroscience initiative aims to accelerate anti‑aging therapies

Albert Einstein College of Medicine has launched the Batia and Idan Ofer program for Validation of Interventions Targeting Aging and Longevity (BIO-VITAL), a new initiative designed to help biotechnology and pharmaceutical companies advance therapies that target the biology of aging.

9 Jun 2026

New game-based therapy retrains muscles after a stroke

A customized throw-back video game may offer a surprisingly futuristic path to stroke recovery.

9 Jun 2026

Massive genetic study uncovers new insights into anxiety risk

A study led by researchers at King’s College London and QIMR Berghofer medical research institute analysed genetic data on anxiety symptoms in 693,869 people of European ancestry, revealing new insight into the genetic pathways involved in the condition.

9 Jun 2026

Scientists use inactive virus to safe-deliver spasticity-reversing spinal genes

Muscle spasticity is a common and often debilitating consequence of spinal cord injury that can significantly affect mobility and quality of life. Spasticity is a condition in which muscles become abnormally stiff or tight because of disrupted nerve signaling, often causing exaggerated reflexes, involuntary muscle spasms and difficulty with movement.

9 Jun 2026