Omicron News and Research

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Nasal antibodies decline nine months after COVID-19 infection, study finds

A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year.

20 Dec 2022

Seasonal influenza activity remains high but appears to be declining in some areas of the US

The weekly FluView Report mentions that the number of influenza cases seems to be declining in some areas in the United States. However, the overall seasonal influenza activity remains high.

19 Dec 2022

Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2

Researchers demonstrated that a trivalent vaccine against SARS-CoV-2 improved the breadth of humoral immune responses in mice.

19 Dec 2022

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Researchers reported the waning of antibodies against SARS-CoV-2 in the six months following a booster dose of the mRNA COVID-19 vaccine.

19 Dec 2022

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

Researchers evaluated the immunogenicity and safety of the COVID-19 bivalent mRNA vaccine mRNA-1273.222 and tested the neutralizing ability of the two bivalent vaccines — mRNA-1273.222 and mRNA-1273.214 — against the newly emergent Omicron subvariants.

19 Dec 2022

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

A new study in the journal Vaccines aimed to analyze the long-term kinetics of SARS-CoV-2 specific T cell and humoral responses following primary and booster vaccinations in previously infected individuals.

18 Dec 2022

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Researchers developed a one-dose subunit vaccine for the induction of durable, potent, and broad immunity against SARS-CoV-2.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

Researchers demonstrated the exceptional immune evasion properties of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, BQ and XBB.

16 Dec 2022

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

A recent study reported that in the two years following the initiation of the US COVID-19 vaccination campaign, over 18 million hospitalizations and three million deaths have been prevented, and close to $1.15 trillion have been saved in medical costs.

16 Dec 2022

Study finds disparities in health care coverage, hampered COVID-19 vaccination efforts in rural areas

Vaccine hesitancy is just one reason fewer people in some parts of the United States have been inoculated against coronavirus.

16 Dec 2022

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Scientists identify an immunogenic epitope at the furin cleavage site of the SARS-CoV-2 spike protein.

15 Dec 2022

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Researchers evaluated the emergence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Canada.

15 Dec 2022

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Researchers used sheep, a ruminant mammal, to obtain polyclonal immunoglobulins (IgGs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Dec 2022

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Researchers estimated influenza VE in patients aged ≥6 months seeking outpatient care for ARI due to the influenza A(H3N2) virus between October 2021 and April 2022 in the United States (US).

15 Dec 2022

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

An early release from the CDC, USA, examines the coverage of booster doses among adults in the USA.

15 Dec 2022

‘Cocktail’ vaccines could offer protection against current and future SARS-CoV-2 'variants of concern'

COVID-19 vaccinations that combine two or more distinct variants of the SARS-CoV-2 virus could offer protection against both current and future 'variants of concern', say scientists at the University of Cambridge and Medical University of Innsbruck.

15 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

Researchers analyzed the mortality in selected countries during multiple waves of the COVID-19 pandemic in 2020 and 2021 to understand the evolution of COVID-19-related mortality according to age and sex.

14 Dec 2022

Omicron News and Research

Nasal antibodies decline nine months after COVID-19 infection, study finds

Seasonal influenza activity remains high but appears to be declining in some areas of the US

Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

Study finds disparities in health care coverage, hampered COVID-19 vaccination efforts in rural areas

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

‘Cocktail’ vaccines could offer protection against current and future SARS-CoV-2 'variants of concern'

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

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