Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process "autophagy."

19 Sep 2022

Study establishes a direct link between disruption of circadian clocks and lipid changes in diabetics

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function.

19 Sep 2022

AI used to identify pancreatic cancer in CT scans

In a recent study published in the journal Radiology, researchers in Taiwan developed a deep learning (DL)–based computer-aided detection (CAD) tool to detect pancreatic cancer on contrast-enhanced abdominal computed tomography (CT) scans.

15 Sep 2022

Extra caution needed while screening depressed teenagers with Type 1 diabetes

The scoring results of widely used depression-screening tools should be carefully adjusted to better detect the condition in teenagers with Type 1 diabetes mellitus (T1D), according to a new study published in the American Diabetes Association journal Diabetes Care.

14 Sep 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

Deep learning tool highly effective at detecting pancreatic cancer on CT

An artificial intelligence (AI) tool is highly effective at detecting pancreatic cancer on CT, according to a study published in Radiology, a journal of the Radiological Society of North America.

13 Sep 2022

Final results of the PATHFINDER study by GRAIL on multi-cancer early detection tests announced

A new press release announced the results of their interventional PATHFINDER study on the early detection of cancer using multi-cancer early detection (MCED) blood tests.

13 Sep 2022

Incidence of early onset cancers has increased globally, study reveals

Over recent decades, more and more adults under the age of 50 are developing cancer. A study conducted by researchers from Brigham and Women's Hospital reveals that the incidence of early onset cancers (those diagnosed before age 50), including cancers of the breast, colon, esophagus, kidney, liver, and pancreas among others, has dramatically increased around the world, with this drastic rise beginning around 1990.

6 Sep 2022

Researchers use 3D mapping techniques to identify multiple genes implicated in type 2 diabetes

Researchers from Children's Hospital of Philadelphia used advanced three-dimensional mapping techniques at a microscopic level to identify a multitude of genetic variants and corresponding target gene pairings in the pancreas that are implicated in type 2 diabetes.

6 Sep 2022

Integrating recent advances in multi-omics tumor profiling into precision cancer treatment

Tumors have significant differences depending on the person affected, even if they are the same cancer, such as breast cancer.

1 Sep 2022

Tight control of blood sugar in teens may help reduce diabetes-related brain damage

Tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease's damaging effects on the brain, effects which have been shown even in younger children, according to a study published online today in Nature Communications.

30 Aug 2022

Study yields critical clues for successful inflammatory recovery

Inflammation is the body's first line of defense, occurring as droves of immune cells rush to the site of injury or acute illness to make repairs and stem further damage.

22 Aug 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

Researchers reveal details of two key transition points in the development of pancreatic tumors

Pancreatic cancer has few treatment options and limited survival, with only 9% of patients still living five years after diagnosis.

22 Aug 2022

Study to explore why people are at higher risk for developing obesity and diabetes after COVID-19

An Oregon Health & Science University-led team of researchers is exploring why people are at higher risk for developing obesity and diabetes after they get COVID-19.

18 Aug 2022

Eating disorders could be treated by modulating gut microbiota

Researchers describe how the gut-brain axis facilitates communication between the gastrointestinal tract and brain to regulate food consumption behaviors.

17 Aug 2022

Transposable element controls the immune system to favor host survival during virus infection

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection.

11 Aug 2022

Smoking continues to be a leading cause of cancer-related death

A new study led by researchers at the American Cancer Society (ACS) reports nearly 123,000 cancer deaths, or close to 30 percent of all cancer deaths, were from cigarette smoking in the United States in 2019, leading to more than two million Person-Years of Lost Life (PYLL) and nearly $21 billion in annual lost earnings. These losses were disproportionately higher in states with weaker tobacco control policies in the South and Midwest. The results were published today in the International Journal of Cancer.

11 Aug 2022

Interferon beta reduces binding of three components to RBCs, study finds

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Pancreas News and Research

Further Reading

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Study establishes a direct link between disruption of circadian clocks and lipid changes in diabetics

AI used to identify pancreatic cancer in CT scans

Extra caution needed while screening depressed teenagers with Type 1 diabetes

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Deep learning tool highly effective at detecting pancreatic cancer on CT

Final results of the PATHFINDER study by GRAIL on multi-cancer early detection tests announced

Incidence of early onset cancers has increased globally, study reveals

Researchers use 3D mapping techniques to identify multiple genes implicated in type 2 diabetes

Integrating recent advances in multi-omics tumor profiling into precision cancer treatment

Tight control of blood sugar in teens may help reduce diabetes-related brain damage

Study yields critical clues for successful inflammatory recovery

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers reveal details of two key transition points in the development of pancreatic tumors

Study to explore why people are at higher risk for developing obesity and diabetes after COVID-19

Eating disorders could be treated by modulating gut microbiota

Transposable element controls the immune system to favor host survival during virus infection

Smoking continues to be a leading cause of cancer-related death

Interferon beta reduces binding of three components to RBCs, study finds

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

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