Progenitor Cells News and Research

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Research findings may lead to new treatment option for ovarian cancer

A new study has identified an effective combination therapy for treating ovarian cancer cells.

31 Oct 2016

Adult brain cells may be vulnerable to Zika infection, new study suggests

Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.

24 Oct 2016

TSRI scientists elucidate how Zika virus attacks the brains of newborns

In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute have elucidated how the virus attacks the brains of newborns, information that could accelerate the development of treatments.

17 Oct 2016

Penn researchers receive $5.2 million NIH grant to study mechanisms that promote lung regeneration

Penn Medicine researchers, along with colleagues at Cincinnati Children's Hospital and Boston University, have received a $5.2 million, seven-year grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to study the cellular and molecular mechanisms that promote lung regeneration.

13 Oct 2016

URMC scientists receive award to explore new treatments for Huntington's disease

A new award from the CHDI Foundation will advance promising research that aims to slow the progression of Huntington's disease.

13 Oct 2016

Study shows ancient grain varieties may help reduce risk factors for CVD

Eating bread made with ancient grains as part of a healthy diet could help lower cholesterol and blood glucose levels—leading risk factors for heart attack and stroke—according to new research published in the International Journal of Food Sciences and Nutrition.

28 Sep 2016

Department of Defense funds cardiac cell therapy trial for heart failure patients

Building on the results of a recent Cedars-Sinai Heart Institute study published just six months ago, the Department of Defense has awarded a $10 million grant to fund a cardiac cell therapy trial for patients diagnosed with a common but difficult-to-treat form of heart failure.

28 Sep 2016

Gene editing of hematopoietic stem cells can cure many hereditary and congenital diseases

Recent advances in gene editing technology, which allows for targeted repair of disease-causing mutations, can be applied to hematopoietic stem cells with the potential to cure a variety of hereditary and congenital diseases.

23 Sep 2016

Duke, Wisconsin and UAB researchers create bioengineered patches to treat heart failure

The heart cannot regenerate muscle tissue after a heart attack has killed part of the muscle wall, and that dead tissue can strain surrounding muscle, leading to a lethal heart enlargement.

22 Sep 2016

Research findings hold promise for new therapies using proliferating cells to treat patients with FECD

Researchers from Massachusetts Eye and Ear have, for the first time, identified rapidly proliferating cells (known as "neural crest-derived progenitor cells") in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs' Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness.

14 Sep 2016

Real-time MRI guidance could help target and deliver stem cell therapies

Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.

14 Sep 2016

Clinical trial assesses efficacy of experimental treatment in individuals with cervical spinal cord injury

Physicians at Rush University Medical Center became the first in Illinois to inject AST-OPC1 (oligodendrocyte progenitor cells), an experimental treatment, into the damaged cervical spine of a recently paralyzed man as part of a multicenter clinical trial.

14 Sep 2016

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children's Hospital Los Angeles have isolated human nephron progenitor (NP) cells.

12 Sep 2016

New collaborative initiative to develop novel ways of screening drugs for bipolar disorder, schizophrenia

The Johns Hopkins University School of Medicine and the Salk Institute for Biological Studies will co-lead a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced.

2 Sep 2016

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina.

2 Sep 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.

1 Sep 2016

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.

31 Aug 2016

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

In a study focusing on the role of self-donated (autologous) bone marrow-derived endothelial progenitor cells (EPCs) in placental vascular development, researchers in Japan have discovered that when transplanted into pregnant mice, EPCs can contribute to better blood vessel growth that helps in forming "normalized" placental vascularization, leading, in turn, to reduced recurrent miscarriages by providing a healthier fetal environment during gestation.

30 Aug 2016

Skin cells derived from autistic donors grow faster than those from control subjects

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of Medicine.

28 Aug 2016

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Spotlight Innovation Inc. has entered into a Sponsored Research Agreement with Florida State University to support research directed by FSU Prof. Hengli Tang aimed at developing safe and effective drugs to treat patients infected with Zika virus (ZIKV).

27 Aug 2016

Progenitor Cells News and Research

Research findings may lead to new treatment option for ovarian cancer

Adult brain cells may be vulnerable to Zika infection, new study suggests

TSRI scientists elucidate how Zika virus attacks the brains of newborns

Penn researchers receive $5.2 million NIH grant to study mechanisms that promote lung regeneration

URMC scientists receive award to explore new treatments for Huntington's disease

Study shows ancient grain varieties may help reduce risk factors for CVD

Department of Defense funds cardiac cell therapy trial for heart failure patients

Gene editing of hematopoietic stem cells can cure many hereditary and congenital diseases

Duke, Wisconsin and UAB researchers create bioengineered patches to treat heart failure

Research findings hold promise for new therapies using proliferating cells to treat patients with FECD

Real-time MRI guidance could help target and deliver stem cell therapies

Clinical trial assesses efficacy of experimental treatment in individuals with cervical spinal cord injury

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

New collaborative initiative to develop novel ways of screening drugs for bipolar disorder, schizophrenia

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

Skin cells derived from autistic donors grow faster than those from control subjects

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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