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Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

A randomized controlled trial that included more than 300 people diagnosed with chronic spontaneous urticaria (CSU), or hives, found that acupuncture may offer limited relief from the condition, but clinical significance of this finding was unclear.

13 Nov 2023

Rat study suggests hemodialysis plus ketogenic diet could enhance cancer treatment

The study in Scientific Reports investigates the potential of hemodialysis (HD) to sustain elevated blood ketone levels in rats on a ketogenic diet, exploring its use as an adjunct in cancer treatment. Results show that HD maintains ketone levels while reducing glucose and insulin, suggesting a possible enhancement in cancer treatment efficacy.

13 Nov 2023

Novel assay may improve detection and treatment of acute myeloid leukemia

A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

Slumbering among thousands of bacterial strains in a collection of natural specimens at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, several fragile vials held something unexpected, and possibly very useful.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide.

13 Nov 2023

AI-based model can predict therapy outcome in ovarian cancer patients

A model based on artificial intelligence is able to predict the therapy outcome (measured by volumetric reduction of tumor lesions) in 80% of ovarian cancer patients.

13 Nov 2023

Recaticimab injection every 1-3 months may safely lower bad cholesterol

A new PCSK9 inhibitor (recaticimab) injected every one to three months may work safely and provide more flexible dosing to lower cholesterol, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

New drug zilebesiran effectively lowers blood pressure for six months, study finds

A single injection of the experimental medication zilebesiran was safe and effective in reducing systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months, as detailed in the Phase 2 of the KARDIA study, reported as late-breaking science today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Researchers improve the system for stratifying mortality risk of variceal bleeding

Approximately half of patients with advanced liver disease have varicose veins in the esophagus and stomach, and a more than a fifth of them experience bleeding from these varices into the digestive tract.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Psychedelic compounds such as psilocybin, a substance found in various mushroom species, are garnering more research support as novel treatments for psychiatric disorders, but questions remain concerning who they may help the most.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

AdvanCell, a radiopharmaceutical company developing a pipeline of Targeted Alpha Therapies for cancer patients, today announced the first patient was treated with 212Pb-ADVC001, a Targeted Alpha Therapy in development for the treatment of PSMA-positive metastatic Castration-Resistant Prostate Cancer (mCRPC).

13 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Heart attack patients without traditional risk factors have high levels of coronary calcium, study finds

While high cholesterol, high blood pressure, diabetes and smoking are well known heart disease risks, not everyone who has a heart attack has them.

11 Nov 2023

Therapy News and Research

Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

Rat study suggests hemodialysis plus ketogenic diet could enhance cancer treatment

Novel assay may improve detection and treatment of acute myeloid leukemia

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Discovery of two new enzymes offers easier ways to study and manufacture complex natural chemicals

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Unlocking the cure for hepatitis B virus: Challenges and opportunities

AI-based model can predict therapy outcome in ovarian cancer patients

Recaticimab injection every 1-3 months may safely lower bad cholesterol

New drug zilebesiran effectively lowers blood pressure for six months, study finds

Researchers improve the system for stratifying mortality risk of variceal bleeding

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

Revolutionizing critical care: the potential of gut microbiota therapeutics

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

UCI researchers discover gene critical for muscle repair

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Heart attack patients without traditional risk factors have high levels of coronary calcium, study finds

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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