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Scientists discover novel mechanism of action for NK cells in checkpoint inhibitor for cancer

PD-L1 checkpoint inhibitors are a powerful and growing form of immunotherapy used to treat melanoma, kidney cancer, head and neck cancers, Hodgkin's lymphoma and other cancers.

27 Jul 2019

Gut bacteria that prevents mice from becoming obese may also control weight in people

Researchers at University of Utah Health have identified a specific class of bacteria from the gut that prevents mice from becoming obese, suggesting these same microbes may similarly control weight in people.

26 Jul 2019

Researchers demonstrate positive and negative role of LRH-1 during inflammation

Immune cells prevent bacteria, parasites or viruses from entering the body when, for example, the intestinal epithelium is injured.

26 Jul 2019

Defective immune signals could underlie some types of fatal heart disease

Researchers have come up with exciting evidence that confirms the role of abnormal immune signaling in myocarditis.

25 Jul 2019

New vaccine shows promise against toughest HIV strains

A new study reports successful immunization against a so-far invincible “death star” strain of an HIV-related laboratory virus (SIVmac239) and another tough strain. The new approach also achieves long-term protection with a single dose, showing that gene therapy could allow broad and durable protection, based on a modified form of the CD4 protein that allows HIV entry into human cells.

24 Jul 2019

CAR-T cells used to target glioblastoma

Immunotherapy is the new weapon against cancers and building upon existing research, a team of researchers from the Massachusetts General Hospital have devised a way to make immunotherapy more effective in a deadly and common form of brain cancer called glioblastoma.

24 Jul 2019

Researchers discover new blood-borne marker for atrial damage

Atrial fibrillation is a common abnormal heart rhythm. It is treated either with medications or by applying heat or extreme cold to destroy small specific tissue areas in the atrium. This inevitably causes small wounds.

24 Jul 2019

Novel sensor could accelerate diagnosis of sepsis

A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually.

24 Jul 2019

New vaccine containing DNA and recombinant proteins may protect from HIV

Researchers at the Icahn School of Medicine at Mount Sinai have developed a novel vaccine consisting of DNA and recombinant proteins?proteins composed of a portion of an HIV protein and another unrelated protein.

24 Jul 2019

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Pall Corporation, a global leader in filtration, separation and purification, has been chosen by Servier, an independent international pharmaceutical company, as an exclusive technology and services provider for their Gidy, France biomanufacturing facility.

From Pall Corporation 22 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

AI-enabled device detects if targeted chemotherapy is working

A new portable device that utilizes artificial intelligence (AI) and biosensors can rapidly detect if cancer cells thrive after chemotherapy treatment.

17 Jul 2019

Novel vaccine against bee sting allergy successfully tested

A recently completed trial on a bee sting vaccine containing a novel adjuvant called Advax to increase its efficacy has raised hopes that severe allergic reactions, sometimes fatal, to bee venom in allergic people could soon be a thing of the past. The vaccine was designed to neutralize the venom of the European honeybee.

17 Jul 2019

Novel biomarker-guided approach has potential for treatment of common liver cancer

A study at The University of Texas MD Anderson Cancer Center discovered a cellular pathway tied to cancer that may be beneficial in reducing side effects and extending duration of immunotherapy in some patients with hepatocellular carcinoma, the most common form of liver cancer.

16 Jul 2019

New study uncovers 3D structure of toxin responsible for C. diff infection

A new study, led by researchers from the University of California, Irvine, uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating Clostridium difficile infection.

16 Jul 2019

Scripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approach

The Scripps Consortium for HIV/AIDS Vaccine Development, an international collaboration led by Scripps Research, has received a $129 million grant from the National Institutes of Health to advance next-generation vaccines designed to coax the immune system into producing antibodies capable of disarming numerous strains of HIV.

11 Jul 2019

Quanterix to convene leading industry researchers at Alzheimer’s Association International Conference 2019 following closing of UmanDiagnostics acquisition

Quanterix marks major milestones as it continues to expand its footprint in neurology and lead the digital biomarker revolution across healthcare.

From Quanterix 11 Jul 2019

PerkinElmer unveils CE-marked infectious disease immunoassays on EUROIMMUN random access instrument

PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today announced the first two CE-marked chemiluminescence immunoassays (ChLIA) for the detection of anti-Borrelia (Lyme disease) and anti-EBV/EBNA (Epstein-Barr Virus) antibodies on its EUROIMMUN RA Analyzer 10 system.

From Revvity 11 Jul 2019