Enzyme News and Research

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Low levels of cellular copper may make fat cells fatter

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11 Oct 2018

Study shows that one amino acid may produce short-term lowering of glucose levels

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins.

11 Oct 2018

Binge drinking history makes male and female mice react differently to stress, study shows

Researchers with the Veterans Affairs Portland Health Care System and Oregon Health & Sciences University found that a history of binge drinking made male and female mice react differently to traumatic stress.

10 Oct 2018

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

An mRNA platform that can express therapeutic levels of protein in liver tissue could be used to treat patients with rare metabolic disorders.

9 Oct 2018

Study suggests novel approach to treating adults with autism spectrum disorder

A team of scientists at Florida Atlantic University has uncovered a brain-signaling pathway that can be pharmacologically manipulated in genetically engineered mice to reverse an autism-related pathway.

8 Oct 2018

New genome editing tool used to heal genetic disease

Parents of newborns may be familiar with the metabolic disorder phenylketonuria: in Switzerland, all newborn babies are screened for this genetic disease.

8 Oct 2018

New epigenetic screening method could improve cancer detection

Researchers have found a better way to determine the epigenetic code of DNA for the identification of disease, using enzymes instead of bisulphite.

8 Oct 2018

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Leadiant Biosciences, Inc. today announced that the Food and Drug Administration has granted approval to Revcovi (elapegademase-lvlr) injection in the U.S. Revcovi is a new enzyme replacement therapy for the treatment of adenosine deaminase severe combined immune deficiency in pediatric and adult patients.

7 Oct 2018

Common herbicide compound could help fight hospital-acquired fungal infections

A chemical compound found in common herbicides could help fight hospital-acquired human fungal pathogenic infections, which claim an estimated two million lives per year.

4 Oct 2018

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Processed meat consumption may increase breast cancer risk, meta-analysis suggests

Studies on red and processed meat consumption with breast cancer risk have generated inconsistent results. An International Journal of Cancer analysis has now examined all published studies on the topic.

4 Oct 2018

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

Over half of all breast cancers carry genetic defects in the p53 gene, a powerful tumor suppressor. Loss of this gene increases the risk of getting breast cancer and the resultant cancers become highly resistant to treatment.

4 Oct 2018

Special glowing paper strip as rapid, reliable test for infectious diseases

Researchers from Eindhoven University of Technology (The Netherlands) and Keio University (Japan) present a practicable and reliable way to test for infectious diseases.

3 Oct 2018

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, have identified the mechanism by which an important enzyme involved in the differentiation of stem cells is brought to the DNA.

3 Oct 2018

Study highlights need for population-specific precision medicine programs in Latin America

Drug safety and effectiveness vary greatly among populations worldwide. Genetics is one of the factors that contribute to variability in drug response.

3 Oct 2018

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Vitamin E's positive effects often fail to manifest themselves as strongly as expected, but sometimes administering vitamin E actually has detrimental effects. An international team has now found a possible cause for this.

3 Oct 2018

Novel discovery could help to improve success of corneal transplants

A team of eye specialists at The University of Nottingham has made another novel discovery that could help to improve the success of corneal transplants for patients whose sight has been affected by disease.

1 Oct 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

New combination therapy shows potential in treating incurable HPV-related cancers

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

28 Sep 2018

Food scientists can employ bacteriophage to destroy E. coli in drinking water

To rapidly detect the presence of E. coli in drinking water, Cornell University food scientists now can employ a bacteriophage - a genetically engineered virus - in a test used in hard-to-reach areas around the world.

28 Sep 2018

Enzyme News and Research

Low levels of cellular copper may make fat cells fatter

Study shows that one amino acid may produce short-term lowering of glucose levels

Binge drinking history makes male and female mice react differently to stress, study shows

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

Study suggests novel approach to treating adults with autism spectrum disorder

New genome editing tool used to heal genetic disease

New epigenetic screening method could improve cancer detection

Leadiant Biosciences announces FDA approval of Revcovi for treating pediatric, adult ADA-SCID patients

Common herbicide compound could help fight hospital-acquired fungal infections

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Processed meat consumption may increase breast cancer risk, meta-analysis suggests

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

Special glowing paper strip as rapid, reliable test for infectious diseases

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Study highlights need for population-specific precision medicine programs in Latin America

Researchers decode anti-inflammatory mechanism of vitamin E and its metabolites

Novel discovery could help to improve success of corneal transplants

Researchers deplete key protein for DNA replication using protein degradation system

New combination therapy shows potential in treating incurable HPV-related cancers

Food scientists can employ bacteriophage to destroy E. coli in drinking water

Understanding the DNA Damage Response in Innate Immunity eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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