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ACCORDION study shows lowering blood glucose can reduce progression of diabetic retinopathy

People with type 2 diabetes who intensively controlled their blood sugar level during the landmark Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial Eye Study were found to have cut their risk of diabetic retinopathy in half in a follow-up analysis conducted four years after stopping intensive therapy.

13 Jun 2016

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

Study highlights role of intestinal calcium absorption in kidney stone formation

Measuring intestinal calcium absorption may help to identify individuals who are prone to develop kidney stones, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

10 Jun 2016

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

9 Jun 2016

Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs.

9 Jun 2016

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

9 Jun 2016

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Identifying the cell of origin is crucial to understanding how a tumor develops and metastasizes and for developing targeted therapies.

8 Jun 2016

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

While hospitalizations related to rheumatoid arthritis have dropped considerably over the past two decades, hospitalizations primarily associated with gout have increased dramatically.

8 Jun 2016

TAVI matches SAVR for early and midterm mortality

Transcatheter aortic valve implantation has similar early and midterm mortality to surgical aortic valve replacement in patients with aortic stenosis, including those at low to intermediate risk, show results of a systematic review and meta-analysis.

8 Jun 2016

Nivolumab drug benefits metastatic RCC patients who continued treatment beyond progression

In a large randomized study, the immunotherapy drug nivolumab, a checkpoint inhibitor, was shown to be a safe and effective therapy for kidney cancer even in patients who continued treatment after their disease progressed.

7 Jun 2016

Overtesting for HbA1C levels can increase risk of severe hypoglycemia

With a more-is-better mindset common in society, frequent commercials encouraging checks of glycated hemoglobin (HbA1C) levels, and ads for new diabetes medications to lower HbA1C in adults with Type 2 diabetes, Mayo Clinic researchers were not too surprised to find overtesting occurring.

7 Jun 2016

Drinking soft drinks to rehydrate worsens dehydration-related kidney injury

Repeated heat-related dehydration has been associated with increased risk of chronic kidney damage in mice. A new study in rats published in the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology reports that drinking soft drinks to rehydrate worsened dehydration and kidney injury.

7 Jun 2016

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.

7 Jun 2016

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National Cancer Institute of the US.

7 Jun 2016

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.

6 Jun 2016

Combination therapy equally good at treating small cell lung cancer

HAVING radiotherapy once a day for six and a half weeks or twice a day for three weeks -- when combined with chemotherapy -- is equally good at treating small cell lung cancer that hasn't spread.

6 Jun 2016

Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

A new drug that harnesses the immune system to attack tumors is highly effective against advanced bladder cancer, according to the results of an international clinical trial to be presented June 5 at the annual meeting of the American Society for Clinical Oncology.

6 Jun 2016

Nivolumab drug shows better response rate in metastatic bladder cancer patients

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center.

6 Jun 2016

DRD2 expression plays crucial role in protecting mice against kidney injury, hypertension

Dopamine signaling in the kidneys plays a critical role in blood pressure regulation and is responsible for nearly half of the salt and water excretion that occurs in response to increased dietary salt intake. Notably, genetic deletion of any of the 5 dopamine receptors expressed in the kidney causes hypertension in mice.

3 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

Kidney News and Research

ACCORDION study shows lowering blood glucose can reduce progression of diabetic retinopathy

Carfilzomib therapy shows promise for pre-kidney transplant patients

Study highlights role of intestinal calcium absorption in kidney stone formation

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

Mathematical approach can help achieve optimal dosing for various drugs

Researchers investigate causes of renal failure using mathematical model

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

TAVI matches SAVR for early and midterm mortality

Nivolumab drug benefits metastatic RCC patients who continued treatment beyond progression

Overtesting for HbA1C levels can increase risk of severe hypoglycemia

Drinking soft drinks to rehydrate worsens dehydration-related kidney injury

Eculizumab drug provides new hope for kidney failure patients

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Scientists use X-rays to study how eculizumab prevents immune system from damaging kidney tissue

Combination therapy equally good at treating small cell lung cancer

Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

Nivolumab drug shows better response rate in metastatic bladder cancer patients

DRD2 expression plays crucial role in protecting mice against kidney injury, hypertension

Scientists use new technique to repair fibrotic liver cells within the organ

Event guide: 8th CKD Summit 2026 eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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